STRINGSTRING
acsA acsA AIW12959.1 AIW12959.1 torD torD AIW13653.1 AIW13653.1 AIW13654.1 AIW13654.1 AIW13835.1 AIW13835.1 AIW13871.1 AIW13871.1 AIW14075.1 AIW14075.1 AIW14076.1 AIW14076.1 AIW14077.1 AIW14077.1 AIW14093.1 AIW14093.1 serC serC ackA ackA AIW14489.1 AIW14489.1 glyA glyA AIW14933.1 AIW14933.1 eno eno AIW15069.1 AIW15069.1 AIW15116.1 AIW15116.1 mdh mdh AIW15164.1 AIW15164.1 fbp fbp gpmI gpmI pfkA pfkA ppc ppc AIW15326.1 AIW15326.1 AIW15335.1 AIW15335.1 AIW15336.1 AIW15336.1 AIW15822.1 AIW15822.1 glyA-2 glyA-2 AIW15964.1 AIW15964.1 ackA-2 ackA-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa)
AIW12959.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (358 aa)
torDMolecular chaperone TorD; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; Belongs to the TorD/DmsD family. TorD subfamily. (215 aa)
AIW13653.1Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TorC/TorY family. (394 aa)
AIW13654.1Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (820 aa)
AIW13835.1Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
AIW13871.1Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
AIW14075.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
AIW14076.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
AIW14077.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (951 aa)
AIW14093.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (314 aa)
serCMFS transporter; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (360 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
AIW14489.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (721 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (416 aa)
AIW14933.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (432 aa)
AIW15069.1D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (409 aa)
AIW15116.1Glycerate dehydrogenase; Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (310 aa)
AIW15164.1Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
fbpCatalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. (338 aa)
gpmIPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (510 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (877 aa)
AIW15326.1Fructose 1,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
AIW15335.1S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (279 aa)
AIW15336.1Catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione; also catalyzes the formation of aldehyde or ketone from alcohols; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (382 aa)
AIW15822.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1403 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa)
AIW15964.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (789 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
Your Current Organism:
Vibrio tubiashii
NCBI taxonomy Id: 1051646
Other names: V. tubiashii ATCC 19109, Vibrio tubiashii ATCC 19109, Vibrio tubiashii LMG 10396, Vibrio tubiashii NBRC 15644, Vibrio tubiashii str. ATCC 19109, Vibrio tubiashii strain ATCC 19109
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