STRINGSTRING
AIW12827.1 AIW12827.1 secY secY fur-2 fur-2 ffh ffh AIW13047.1 AIW13047.1 AIW13075.1 AIW13075.1 AIW13076.1 AIW13076.1 AIW13077.1 AIW13077.1 AIW13078.1 AIW13078.1 AIW13079.1 AIW13079.1 AIW13138.1 AIW13138.1 yajC yajC AIW13301.1 AIW13301.1 AIW13802.1 AIW13802.1 AIW13803.1 AIW13803.1 AIW13804.1 AIW13804.1 AIW14016.1 AIW14016.1 AIW14144.1 AIW14144.1 AIW14270.1 AIW14270.1 ribA ribA AIW14341.1 AIW14341.1 AIW14342.1 AIW14342.1 AIW14492.1 AIW14492.1 oppD oppD AIW14494.1 AIW14494.1 oppB oppB AIW14496.1 AIW14496.1 AIW14582.1 AIW14582.1 AIW14704.1 AIW14704.1 AIW14705.1 AIW14705.1 ribD ribD secA secA AIW15007.1 AIW15007.1 AIW15072.1 AIW15072.1 luxS luxS hfq hfq secE secE AIW15295.1 AIW15295.1 secB secB ftsY ftsY AIW15411.1 AIW15411.1 AIW15412.1 AIW15412.1 AIW15413.1 AIW15413.1 AIW15414.1 AIW15414.1 yidC yidC AIW15612.1 AIW15612.1 AIW15680.1 AIW15680.1 AIW15781.1 AIW15781.1 oppD-2 oppD-2 AIW15783.1 AIW15783.1 oppB-2 oppB-2 AIW15785.1 AIW15785.1 AIW16159.1 AIW16159.1 AIW16183.1 AIW16183.1 AIW16383.1 AIW16383.1 AIW16384.1 AIW16384.1 AIW16497.1 AIW16497.1 AIW16498.1 AIW16498.1 AIW16811.1 AIW16811.1 AIW17010.1 AIW17010.1 AIW17075.1 AIW17075.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIW12827.1Crp/Fnr family transcriptional regulator; cAMP receptor protein; complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
secYPreprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (444 aa)
fur-2XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. (154 aa)
ffhSignal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belo [...] (462 aa)
AIW13047.1LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
AIW13075.1Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (331 aa)
AIW13076.1Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (327 aa)
AIW13077.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
AIW13078.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
AIW13079.1Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa)
AIW13138.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (357 aa)
yajCPreprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (109 aa)
AIW13301.1Peptidase S8; Derived by automated computational analysis using gene prediction method: Protein Homology. (784 aa)
AIW13802.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (705 aa)
AIW13803.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (835 aa)
AIW13804.1Autoinducer synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
AIW14016.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (350 aa)
AIW14144.1LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (489 aa)
AIW14270.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (777 aa)
ribAGTP cyclohydrolase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (215 aa)
AIW14341.1With component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (520 aa)
AIW14342.1Anthranilate synthase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
AIW14492.1Peptide ABC transporter ATP-binding protein; With OppABCD is involved in the transport of oligopeptides; OppF and OppD are ATP-binding proteins; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
oppDOligopeptide transporter ATP-binding component; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (323 aa)
AIW14494.1Peptide ABC transporter permease; With OppABDF is involved in the transport of oligopeptides of up to 5 amino acids into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
oppBOligopeptide transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
AIW14496.1Peptide ABC transporter substrate-binding protein; Is involved in the transport of the murein peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate; Derived by automated computational analysis using gene prediction method: Protein Homology. (556 aa)
AIW14582.1Long-chain fatty acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)
AIW14704.1Phosphorelay protein LuxU; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
AIW14705.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
ribD5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (368 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (909 aa)
AIW15007.1Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (110 aa)
AIW15072.1Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (602 aa)
luxSS-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (172 aa)
hfqRNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. (87 aa)
secEPreprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (126 aa)
AIW15295.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
secBPreprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (155 aa)
ftsYCell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (394 aa)
AIW15411.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
AIW15412.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
AIW15413.1Derived by automated computational analysis using gene prediction method: Protein Homology. (517 aa)
AIW15414.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (571 aa)
yidCMembrane protein insertase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (539 aa)
AIW15612.1Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2051 aa)
AIW15680.1Alkaline serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family. (527 aa)
AIW15781.1Peptide ABC transporter ATP-binding protein; With OppABCD is involved in the transport of oligopeptides; OppF and OppD are ATP-binding proteins; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
oppD-2Oligopeptide transporter ATP-binding component; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (329 aa)
AIW15783.1Peptide ABC transporter permease; With OppABDF is involved in the transport of oligopeptides of up to 5 amino acids into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
oppB-2Oligopeptide transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
AIW15785.1Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (536 aa)
AIW16159.1Antibiotic biosynthesis monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
AIW16183.1Peptide ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (540 aa)
AIW16383.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (848 aa)
AIW16384.1ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
AIW16497.1CAI-1 autoinducer synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
AIW16498.1Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (684 aa)
AIW16811.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (351 aa)
AIW17010.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (3488 aa)
AIW17075.1Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (282 aa)
Your Current Organism:
Vibrio tubiashii
NCBI taxonomy Id: 1051646
Other names: V. tubiashii ATCC 19109, Vibrio tubiashii ATCC 19109, Vibrio tubiashii LMG 10396, Vibrio tubiashii NBRC 15644, Vibrio tubiashii str. ATCC 19109, Vibrio tubiashii strain ATCC 19109
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