STRINGSTRING
GYO_4423 GYO_4423 GYO_4419 GYO_4419 ahpF ahpF GYO_4405 GYO_4405 GYO_4388 GYO_4388 GYO_4356 GYO_4356 GYO_4348 GYO_4348 GYO_4334 GYO_4334 GYO_4315 GYO_4315 GYO_4311 GYO_4311 GYO_4307 GYO_4307 GYO_4285 GYO_4285 GYO_4278 GYO_4278 cydD cydD GYO_4274 GYO_4274 GYO_4266 GYO_4266 GYO_4261 GYO_4261 GYO_4260 GYO_4260 GYO_4259 GYO_4259 GYO_4238 GYO_4238 GYO_4235 GYO_4235 GYO_4218 GYO_4218 qoxA qoxA qoxB qoxB qoxC qoxC qoxD qoxD GYO_4195 GYO_4195 GYO_4102 GYO_4102 atpA atpA atpD atpD rbsA rbsA GYO_3942 GYO_3942 tagH tagH secA secA GYO_3818 GYO_3818 GYO_3800 GYO_3800 GYO_3794 GYO_3794 GYO_3793 GYO_3793 yveA yveA yvfH yvfH GYO_3747 GYO_3747 GYO_3746 GYO_3746 GYO_3721 GYO_3721 GYO_3695 GYO_3695 GYO_3690 GYO_3690 GYO_3689 GYO_3689 secG secG GYO_3663 GYO_3663 GYO_3662 GYO_3662 GYO_3654 GYO_3654 GYO_3644 GYO_3644 GYO_3638 GYO_3638 metN metN GYO_3559 GYO_3559 GYO_3555 GYO_3555 GYO_3511 GYO_3511 GYO_3456 GYO_3456 GYO_3455 GYO_3455 GYO_3454 GYO_3454 GYO_3453 GYO_3453 GYO_3452 GYO_3452 nha nha cpa cpa GYO_3447 GYO_3447 GYO_3388 GYO_3388 GYO_3330 GYO_3330 GYO_3277 GYO_3277 GYO_3124 GYO_3124 GYO_3118 GYO_3118 GYO_3021 GYO_3021 secDF secDF GYO_2940 GYO_2940 GYO_2939 GYO_2939 GYO_2887 GYO_2887 GYO_2886 GYO_2886 pnaS pnaS pstC pstC pstA pstA pstB-2 pstB-2 pstB pstB GYO_2641 GYO_2641 GYO_2592 GYO_2592 kdgT kdgT GYO_2394 GYO_2394 GYO_2346 GYO_2346 bass bass GYO_2336 GYO_2336 GYO_2313 GYO_2313 GYO_2206 GYO_2206 GYO_2182 GYO_2182 GYO_2119 GYO_2119 GYO_2111 GYO_2111 fliI fliI GYO_1914 GYO_1914 GYO_1907 GYO_1907 GYO_1881 GYO_1881 ctaF ctaF GYO_1835 GYO_1835 ctaD ctaD coxB coxB GYO_1776 GYO_1776 GYO_1769 GYO_1769 GYO_1768 GYO_1768 GYO_1723 GYO_1723 GYO_1717 GYO_1717 GYO_1645 GYO_1645 GYO_1601 GYO_1601 GYO_1540 GYO_1540 GYO_1533 GYO_1533 GYO_1504 GYO_1504 GYO_1503 GYO_1503 GYO_1469 GYO_1469 GYO_1388 GYO_1388 GYO_1348 GYO_1348 GYO_1320 GYO_1320 GYO_1300 GYO_1300 GYO_1276 GYO_1276 GYO_1263 GYO_1263 GYO_1262 GYO_1262 GYO_1259 GYO_1259 GYO_1236 GYO_1236 GYO_1201 GYO_1201 GYO_1197 GYO_1197 GYO_1170 GYO_1170 GYO_1137 GYO_1137 GYO_1094 GYO_1094 GYO_1090 GYO_1090 GYO_1089 GYO_1089 GYO_1088 GYO_1088 cax cax treP treP GYO_1040 GYO_1040 GYO_1037 GYO_1037 GYO_1027 GYO_1027 GYO_0958 GYO_0958 GYO_0928 GYO_0928 GYO_0879 GYO_0879 GYO_0872 GYO_0872 tatCy tatCy GYO_0841 GYO_0841 GYO_0839 GYO_0839 GYO_0809 GYO_0809 GYO_0670 GYO_0670 GYO_0668 GYO_0668 dctA dctA GYO_0658 GYO_0658 mntH mntH GYO_0634 GYO_0634 GYO_0616 GYO_0616 GYO_0615 GYO_0615 GYO_0574 GYO_0574 GYO_0528 GYO_0528 GYO_0510 GYO_0510 GYO_0502 GYO_0502 GYO_0489 GYO_0489 GYO_0477 GYO_0477 GYO_0476 GYO_0476 tatCd tatCd GYO_0457 GYO_0457 GYO_0440 GYO_0440 ptsG ptsG GYO_0432 GYO_0432 glpT glpT GYO_0402 GYO_0402 GYO_0376 GYO_0376 GYO_0360 GYO_0360 GYO_0350 GYO_0350 GYO_0349 GYO_0349 yveK yveK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GYO_4423ABC transporter, ATP-binding protein. (209 aa)
GYO_4419Pts system beta-glucoside-specific eiibca component. (622 aa)
ahpFAlkyl hydroperoxide reductase, F subunit. (509 aa)
GYO_4405Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (525 aa)
GYO_4388Arabinose-proton symporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (461 aa)
GYO_4356Putative amino-acid ABC transporter ATP-binding protein YtmN. (249 aa)
GYO_4348Pyrimidine nucleoside transport protein; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (393 aa)
GYO_4334Pts system beta-glucoside-specific eiibca component. (612 aa)
GYO_4315Pts system beta-glucoside-specific eiibca component. (610 aa)
GYO_4311Citrate transporter. (426 aa)
GYO_4307YxjA; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (397 aa)
GYO_4285Multiple sugar-binding transport ATP-binding protein MsmK; Belongs to the ABC transporter superfamily. (365 aa)
GYO_4278Citrate/malate transporter. (450 aa)
cydDABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD. (567 aa)
GYO_4274ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC. (575 aa)
GYO_4266YxlG. (258 aa)
GYO_4261HTH domain family. (641 aa)
GYO_4260Lichenan-specific phosphotransferase enzyme IIB component. (102 aa)
GYO_4259PTS system, cellobiose-specific IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (452 aa)
GYO_4238Pts system, sucrose-specific iibc component. (459 aa)
GYO_4235PTS system, cellobiose-specific IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (440 aa)
GYO_4218YwcA; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (513 aa)
qoxACytochrome aa3 quinol oxidase, subunit II; Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I. (318 aa)
qoxBCytochrome aa3 quinol oxidase, subunit I; Belongs to the heme-copper respiratory oxidase family. (649 aa)
qoxCCytochrome aa3 quinol oxidase, subunit III. (204 aa)
qoxDCytochrome aa3 quinol oxidase, subunit IV. (124 aa)
GYO_4195PTS system sucrose-specific EIIBC component. (461 aa)
GYO_4102ABC transporter transmembrane region family protein. (574 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (502 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (473 aa)
rbsARibose transport ATP-binding protein RbsA; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (493 aa)
GYO_3942Sugar transporter family protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (457 aa)
tagHTeichoic acids export ATP-binding protein TagH; Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system. (527 aa)
secAPreprotein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (841 aa)
GYO_3818Multidrug resistance ABC transporter ATP-binding and permease protein. (589 aa)
GYO_3800Sulfate permease family protein. (530 aa)
GYO_3794YvdH. (435 aa)
GYO_3793YvdI. (278 aa)
yveAAspartate-proton symporter. (520 aa)
yvfHLactate peamease family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (563 aa)
GYO_3747YvfL. (418 aa)
GYO_3746YvfM. (283 aa)
GYO_3721Arabinose-proton symporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (464 aa)
GYO_3695Conserved hypothetical protein. (614 aa)
GYO_3690SpaE. (251 aa)
GYO_3689SpaG. (203 aa)
secGPutative protein-export membrane protein SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (76 aa)
GYO_3663Copper-translocating P-type ATPase. (803 aa)
GYO_3662Cadmium-translocating P-type ATPase. (699 aa)
GYO_3654Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (670 aa)
GYO_3644YvsH. (469 aa)
GYO_3638Ferrichrome transport ATP-binding protein FhuC. (269 aa)
metNYusC; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (341 aa)
GYO_3559ABC sugar transporter, inner membrane subunit. (292 aa)
GYO_3555Putative ABC transporter ATP-binding protein YcjV; Belongs to the ABC transporter superfamily. (367 aa)
GYO_3511Nucleoside transporter, NupC family protein; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (404 aa)
GYO_3456Na(+)/H(+) antiporter subunit G. (124 aa)
GYO_3455Na(+)/H(+) antiporter subunit F. (94 aa)
GYO_3454Na(+)/H(+) antiporter subunit E. (158 aa)
GYO_3453Na(+)/H(+) antiporter subunit D. (496 aa)
GYO_3452Na(+)/H(+) antiporter subunit C. (113 aa)
nhaNa(+)/H(+) antiporter subunit B. (143 aa)
cpaMonovalent cation:proton antiporter subfamily. (801 aa)
GYO_3447Na(+)-malate symporter. (448 aa)
GYO_3388Cation transport protein, putative. (445 aa)
GYO_3330Manganese transport system ATP-binding protein MntB. (250 aa)
GYO_3277Sugar transport protein. (303 aa)
GYO_3124L-arabinose transport system permease protein AraP. (313 aa)
GYO_3118Carbon starvation protein CstA, putative. (598 aa)
GYO_3021Sodium:alanine symporter. (484 aa)
secDFSecDF protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (737 aa)
GYO_2940Fructose-specific phosphotransferase enzyme IIB component. (162 aa)
GYO_2939Fructose permease IIC component. (269 aa)
GYO_2887Copper-translocating P-type ATPase. (812 aa)
GYO_2886Pts system beta-glucoside-specific eiibca component. (617 aa)
pnaSNa/Pi-cotransporter II-related protein. (307 aa)
pstCPhosphate ABC transporter, permease protein PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (309 aa)
pstAPhosphate ABC transporter, permease protein PstA. (294 aa)
pstB-2Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (248 aa)
pstBPhosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (242 aa)
GYO_2641YqiZ. (240 aa)
GYO_2592na+/H+ antiporter NhaC. (468 aa)
kdgT2-keto-3-deoxygluconate permease. (330 aa)
GYO_2394MATE efflux family protein. (445 aa)
GYO_2346Multidrug resistance protein NorM. (452 aa)
bassBile acid transporter family protein. (321 aa)
GYO_2336YocR; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (445 aa)
GYO_2313YozB. (178 aa)
GYO_2206YoeA protein. (463 aa)
GYO_2182Amino acid carrier protein AlsT. (465 aa)
GYO_2119Arabinose-proton symporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (468 aa)
GYO_2111Hypothetical protein. (463 aa)
fliIFlagellar protein export ATPase FliI. (427 aa)
GYO_1914E1-E2 ATPase subfamily, putative. (890 aa)
GYO_1907Phosphate transporter family protein. (354 aa)
GYO_1881ABC transporter family protein. (264 aa)
ctaFCytochrome c oxidase, subunit IV. (110 aa)
GYO_1835cytoChrome c oxidase subunit 3. (207 aa)
ctaDCytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (622 aa)
coxBcytoChrome c oxidase subunit 2; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). (356 aa)
GYO_1776Fructose permease IIC component. (634 aa)
GYO_1769ABC transporter, ATP-binding protein. (604 aa)
GYO_1768ABC transporter, ATP-binding protein. (594 aa)
GYO_1723PTS system glucose-specific EIICBA component. (699 aa)
GYO_1717Cadmium-translocating P-type ATPase. (637 aa)
GYO_1645YkoD. (546 aa)
GYO_1601Pit. (333 aa)
GYO_1540YjmB. (459 aa)
GYO_1533Glutamine transport ATP-binding protein glnQ; Belongs to the ABC transporter superfamily. (250 aa)
GYO_1504Phosphotransferase system. (650 aa)
GYO_1503HTH domain family. (648 aa)
GYO_1469YjbQ; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (614 aa)
GYO_1388YisQ. (456 aa)
GYO_1348Sodium/pantothenate symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (489 aa)
GYO_1320Proton/sodium-glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (429 aa)
GYO_1300Protein EcsC. (236 aa)
GYO_1276Sodium/hydrogen exchanger family protein. (405 aa)
GYO_1263ABC transporter, ATP-binding protein. (673 aa)
GYO_1262YheI. (585 aa)
GYO_1259Na(+)/H(+) antiporter. (453 aa)
GYO_1236YhdH; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (451 aa)
GYO_1201Putative symporter YdjN; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (463 aa)
GYO_1197YhcI. (313 aa)
GYO_1170SsuA. (332 aa)
GYO_1137YgaD. (580 aa)
GYO_1094Major myo-inositol transporter IolT; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (482 aa)
GYO_1090ABC transporter. (604 aa)
GYO_1089Multidrug ABC transporter ATP-binding protein. (573 aa)
GYO_1088Pts system maltose-specific eiicb component. (527 aa)
caxCalcium/proton exchanger; Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons. (351 aa)
trePPts system, trehalose-specific iibc component. (470 aa)
GYO_1040YflA. (471 aa)
GYO_1037PTS system N-acetylglucosamine-specific EIICBA component. (452 aa)
GYO_1027Mg(2+)/citrate complex secondary transporter. (433 aa)
GYO_0958Inner membrane protein. (301 aa)
GYO_0928Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (492 aa)
GYO_0879Major myo-inositol transporter IolT; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (473 aa)
GYO_0872Putative glucitol transport protein GutA. (458 aa)
tatCyTwin arginine-targeting protein translocase TatCy; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. (251 aa)
GYO_0841PTS system, cellobiose-specific IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (442 aa)
GYO_0839Cellobiose-specific phosphotransferase enzyme IIB component. (103 aa)
GYO_0809Sugar transporter family protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (447 aa)
GYO_0670YdbK. (255 aa)
GYO_0668Proton/sodium-glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (412 aa)
dctAAerobic C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (421 aa)
GYO_0658YdbA. (272 aa)
mntHManganese transport protein MntH; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family. (424 aa)
GYO_0634HTH domain family. (696 aa)
GYO_0616Pts system mannitol-specific eiicba component. (143 aa)
GYO_0615Pts system mannitol-specific eiicba component. (477 aa)
GYO_0574YckI. (247 aa)
GYO_0528Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (476 aa)
GYO_0510L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (541 aa)
GYO_0502Glycine betaine transport ATP-binding protein opuAA. (418 aa)
GYO_0489Zinc uptake system ATP-binding protein zurA. (231 aa)
GYO_0477Protein NatB. (386 aa)
GYO_0476ATP-binding transport protein NatA. (246 aa)
tatCdSec-independent protein translocase protein TatCd; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. (241 aa)
GYO_0457YcbO. (204 aa)
GYO_0440Amino acid carrier protein AlsT. (478 aa)
ptsGPts system, glucose-specific iibc component. (631 aa)
GYO_0432Proton glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (414 aa)
glpTGlycerol-3-phosphate transporter. (444 aa)
GYO_0402Sodium-dependent phosphate transporter. (542 aa)
GYO_0376Putative NADH-quinone oxidoreductase subunit 5. (505 aa)
GYO_0360YbbF. (455 aa)
GYO_0350YbaS. (319 aa)
GYO_0349YbaR. (478 aa)
yveKCobalt import ATP-binding protein CbiO 1; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (281 aa)
Your Current Organism:
Bacillus subtilis spizizenii
NCBI taxonomy Id: 1052585
Other names: B. subtilis subsp. spizizenii TU-B-10, Bacillus subtilis subsp. spizizenii TU-B-10, Bacillus subtilis subsp. spizizenii str. TU-B-10, Bacillus subtilis subsp. spizizenii strain TU-B-10
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