STRINGSTRING
GYO_0504 GYO_0504 GYO_3090 GYO_3090 phoR phoR sppA sppA GYO_3202 GYO_3202 ezrA ezrA GYO_3216 GYO_3216 GYO_3331 GYO_3331 GYO_3340 GYO_3340 GYO_3379 GYO_3379 GYO_3380 GYO_3380 GYO_3407 GYO_3407 GYO_4368 GYO_4368 GYO_4358 GYO_4358 GYO_4221 GYO_4221 qoxA qoxA GYO_4102 GYO_4102 atpH atpH atpA atpA atpG atpG atpD atpD GYO_3955 GYO_3955 gtaB gtaB GYO_3918 GYO_3918 secA secA GYO_3865 GYO_3865 GYO_3661 GYO_3661 bdbC bdbC GYO_3641 GYO_3641 GYO_3640 GYO_3640 GYO_3443 GYO_3443 GYO_3409 GYO_3409 GYO_0014 GYO_0014 ftsH ftsH secY secY GYO_0353 GYO_0353 feuA feuA GYO_0479 GYO_0479 GYO_0488 GYO_0488 mreC mreC GYO_0599 GYO_0599 GYO_0632 GYO_0632 GYO_0925 GYO_0925 GYO_0939 GYO_0939 GYO_1037 GYO_1037 GYO_1065 GYO_1065 GYO_1112 GYO_1112 prsA prsA GYO_1320 GYO_1320 GYO_1335 GYO_1335 oppA oppA oppB oppB ptsI ptsI GYO_1729 GYO_1729 GYO_1730 GYO_1730 GYO_1773 GYO_1773 GYO_1783 GYO_1783 kinC kinC galU galU GYO_2204 GYO_2204 resE resE ccsB ccsB GYO_2570 GYO_2570 GYO_2806 GYO_2806
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GYO_0504Glycine betaine-binding protein. (293 aa)
GYO_3090Succinate dehydrogenase flavoprotein subunit. (586 aa)
phoRAlkaline phosphatase synthesis sensor protein PhoR. (579 aa)
sppASignal peptide peptidase SppA, 36K type. (335 aa)
GYO_3202YtcI. (529 aa)
ezrASeptation ring formation regulator ezrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. (567 aa)
GYO_3216AMP-binding enzyme, putative. (572 aa)
GYO_3331Manganese-binding lipoprotein MntA; Belongs to the bacterial solute-binding protein 9 family. (306 aa)
GYO_3340UTP-glucose-1-phosphate uridylyltransferase. (272 aa)
GYO_3379Epidermal surface antigen. (509 aa)
GYO_3380Conserved hypothetical protein. (191 aa)
GYO_3407Methyl-accepting chemotaxis protein McpA. (661 aa)
GYO_4368Ferrichrome-binding protein. (321 aa)
GYO_4358Amino acid ABC transporter, periplasmic amino acid-binding portion; Belongs to the bacterial solute-binding protein 3 family. (275 aa)
GYO_4221Imelysin family protein. (385 aa)
qoxACytochrome aa3 quinol oxidase, subunit II; Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I. (318 aa)
GYO_4102ABC transporter transmembrane region family protein. (574 aa)
atpHATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (181 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (502 aa)
atpGATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (287 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (473 aa)
GYO_3955D-ribose-binding protein. (305 aa)
gtaBUTP-glucose-1-phosphate uridylyltransferase. (292 aa)
GYO_3918Membrane-bound protein LytR. (221 aa)
secAPreprotein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (841 aa)
GYO_3865Conserved hypothetical protein; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (275 aa)
GYO_3661Disulfide bond formation protein D. (222 aa)
bdbCDisulfide bond formation protein DsbB family protein; Required for disulfide bond formation in some proteins. Belongs to the DsbB family. BdbC subfamily. (138 aa)
GYO_3641Ferrichrome-binding protein. (315 aa)
GYO_3640Ferrichrome transport system permease protein FhuB; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (348 aa)
GYO_3443YufN. (359 aa)
GYO_3409Methyl-accepting chemotaxis protein McpB. (662 aa)
GYO_0014D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (443 aa)
ftsHConserved hypothetical protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (637 aa)
secYPreprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (431 aa)
GYO_0353Iron-uptake system permease protein FeuB; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (334 aa)
feuAIron-uptake system-binding protein. (317 aa)
GYO_0479YcdA. (354 aa)
GYO_0488Zinc-binding lipoprotein adcA; Belongs to the bacterial solute-binding protein 9 family. (325 aa)
mreCRod shape-determining protein MreC; Involved in formation and maintenance of cell shape. (290 aa)
GYO_0599YclQ. (318 aa)
GYO_0632Penicillin-binding Protein dimerization domain family. (654 aa)
GYO_0925Sex pheromone family protein. (396 aa)
GYO_0939YeeF. (629 aa)
GYO_1037PTS system N-acetylglucosamine-specific EIICBA component. (452 aa)
GYO_10653-hydroxyisobutyrate dehydrogenase family protein. (317 aa)
GYO_1112YfiY. (325 aa)
prsAFoldase protein PrsA; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. (284 aa)
GYO_1320Proton/sodium-glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (429 aa)
GYO_1335YhfQ. (323 aa)
oppAOligopeptide-binding protein OppA. (545 aa)
oppBOligopeptide transport system permease protein OppB. (311 aa)
ptsIPhosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (570 aa)
GYO_1729Methyl-accepting chemotaxis protein McpC. (655 aa)
GYO_17303-hydroxyisobutyrate dehydrogenase. (288 aa)
GYO_1773YknZ. (397 aa)
GYO_1783Protein mreBH. (335 aa)
kinCSporulation sensor histidine kinase C. (428 aa)
galUUTP-glucose-1-phosphate uridylyltransferase. (296 aa)
GYO_2204D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase. (491 aa)
resESensor protein histidine kinase resE. (589 aa)
ccsBCytochrome c-type biogenesis protein CcsB. (391 aa)
GYO_2570YpuA. (290 aa)
GYO_2806Protein YqfA. (331 aa)
Your Current Organism:
Bacillus subtilis spizizenii
NCBI taxonomy Id: 1052585
Other names: B. subtilis subsp. spizizenii TU-B-10, Bacillus subtilis subsp. spizizenii TU-B-10, Bacillus subtilis subsp. spizizenii str. TU-B-10, Bacillus subtilis subsp. spizizenii strain TU-B-10
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