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GYO_3638 GYO_3638 secE secE secY secY GYO_4220 GYO_4220 GYO_0352 GYO_0352 GYO_0353 GYO_0353 tatCd tatCd GYO_0473 GYO_0473 GYO_0596 GYO_0596 GYO_0597 GYO_0597 GYO_0631 GYO_0631 tatCy tatCy GYO_0975 GYO_0975 GYO_1015 GYO_1015 GYO_1016 GYO_1016 GYO_1113 GYO_1113 GYO_1114 GYO_1114 GYO_1305 GYO_1305 ftsY ftsY ffh ffh fliR fliR flhF flhF GYO_2608 GYO_2608 secDF secDF GYO_3624 GYO_3624 secA secA GYO_3639 GYO_3639 GYO_3640 GYO_3640 secG secG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GYO_3638Ferrichrome transport ATP-binding protein FhuC. (269 aa)
secEPreprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (59 aa)
secYPreprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (431 aa)
GYO_4220Tat-translocated enzyme; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. (416 aa)
GYO_0352Iron-uptake system permease protein FeuC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (336 aa)
GYO_0353Iron-uptake system permease protein FeuB; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (334 aa)
tatCdSec-independent protein translocase protein TatCd; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. (241 aa)
GYO_0473YccF. (358 aa)
GYO_0596Conserved hypothetical protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (316 aa)
GYO_0597ABC transporter, iron chelate uptake transporter (FeCT) family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (315 aa)
GYO_0631Antibiotic biosynthesis monooxygenase domain protein. (129 aa)
tatCyTwin arginine-targeting protein translocase TatCy; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. (251 aa)
GYO_0975Antibiotic biosynthesis monooxygenase domain protein. (107 aa)
GYO_1015iron(III) dicitrate transport system permease protein FecD; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (333 aa)
GYO_1016Ferrichrome transport system permease protein FhuB; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (320 aa)
GYO_1113Ferrichrome transport system permease protein FhuB; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (333 aa)
GYO_1114Ferrichrome transport system permease protein FhuG; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (343 aa)
GYO_1305YhgC. (166 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (329 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (446 aa)
fliRFlagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (259 aa)
flhFFlagellar biosynthesis protein FlhF. (366 aa)
GYO_2608Antibiotic biosynthesis monooxygenase family protein. (113 aa)
secDFSecDF protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (737 aa)
GYO_3624YvrB; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (290 aa)
secAPreprotein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (841 aa)
GYO_3639Ferrichrome transport system permease protein FhuG; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (336 aa)
GYO_3640Ferrichrome transport system permease protein FhuB; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (348 aa)
secGPutative protein-export membrane protein SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (76 aa)
Your Current Organism:
Bacillus subtilis spizizenii
NCBI taxonomy Id: 1052585
Other names: B. subtilis subsp. spizizenii TU-B-10, Bacillus subtilis subsp. spizizenii TU-B-10, Bacillus subtilis subsp. spizizenii str. TU-B-10, Bacillus subtilis subsp. spizizenii strain TU-B-10
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