STRINGSTRING
GYO_1533 GYO_1533 GYO_1551 GYO_1551 GYO_1564 GYO_1564 GYO_1614 GYO_1614 GYO_1619 GYO_1619 GYO_1645 GYO_1645 GYO_1698 GYO_1698 GYO_1768 GYO_1768 GYO_1769 GYO_1769 GYO_1772 GYO_1772 GYO_1779 GYO_1779 GYO_1881 GYO_1881 ftsY ftsY ffh ffh hslU hslU fliI fliI GYO_2037 GYO_2037 GYO_1195 GYO_1195 ssuB ssuB GYO_1137 GYO_1137 GYO_1100 GYO_1100 GYO_1090 GYO_1090 GYO_1089 GYO_1089 GYO_1079 GYO_1079 GYO_1014 GYO_1014 GYO_1007 GYO_1007 GYO_1000 GYO_1000 GYO_0870 GYO_0870 GYO_0859 GYO_0859 dnaA dnaA dnaX dnaX ftsH ftsH clpC clpC radA radA yveK yveK GYO_0456 GYO_0456 GYO_0476 GYO_0476 GYO_0489 GYO_0489 GYO_0502 GYO_0502 GYO_0553 GYO_0553 GYO_0574 GYO_0574 GYO_0589 GYO_0589 GYO_0598 GYO_0598 GYO_0669 GYO_0669 GYO_0813 GYO_0813 oppF oppF oppD oppD GYO_1441 GYO_1441 GYO_1440 GYO_1440 dnaC dnaC GYO_4444 GYO_4444 GYO_4423 GYO_4423 GYO_4371 GYO_4371 GYO_4356 GYO_4356 GYO_4285 GYO_4285 cydD cydD GYO_4274 GYO_4274 GYO_4267 GYO_4267 GYO_4131 GYO_4131 GYO_4119 GYO_4119 GYO_4102 GYO_4102 rho rho atpD atpD urtD urtD urtE urtE rbsA rbsA tagH tagH GYO_3903 GYO_3903 ftsE ftsE uvrA uvrA GYO_3818 GYO_3818 GYO_3804 GYO_3804 GYO_3741 GYO_3741 GYO_3706 GYO_3706 GYO_3700 GYO_3700 GYO_3695 GYO_3695 GYO_3691 GYO_3691 GYO_3638 GYO_3638 GYO_3636 GYO_3636 GYO_3623 GYO_3623 GYO_3597 GYO_3597 metN metN sufC sufC GYO_3555 GYO_3555 GYO_3444 GYO_3444 GYO_3330 GYO_3330 ytlC ytlC GYO_3296 GYO_3296 GYO_3293 GYO_3293 GYO_3289 GYO_3289 GYO_3249 GYO_3249 GYO_3228 GYO_3228 GYO_3148 GYO_3148 clpX clpX lonB lonB lon lon ruvB ruvB GYO_2992 GYO_2992 recD2 recD2 GYO_2942 GYO_2942 pstB-2 pstB-2 pstB pstB comGA comGA spoIIIAA spoIIIAA GYO_2655 GYO_2655 GYO_2641 GYO_2641 GYO_2341 GYO_2341 GYO_2230 GYO_2230 spoVK spoVK recA recA GYO_1298 GYO_1298 GYO_1281 GYO_1281 GYO_1263 GYO_1263 GYO_1262 GYO_1262 GYO_1196 GYO_1196
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GYO_1533Glutamine transport ATP-binding protein glnQ; Belongs to the ABC transporter superfamily. (250 aa)
GYO_1551Cell-division protein. (423 aa)
GYO_1564Conserved hypothetical protein. (207 aa)
GYO_1614Dipeptide transport ATP-binding protein DppD; Belongs to the ABC transporter superfamily. (335 aa)
GYO_1619Oligopeptide transport ATP-binding protein AppF; Belongs to the ABC transporter superfamily. (329 aa)
GYO_1645YkoD. (546 aa)
GYO_1698ATP-dependent Clp protease ATP-binding subunit clpE; Belongs to the ClpA/ClpB family. (658 aa)
GYO_1768ABC transporter, ATP-binding protein. (594 aa)
GYO_1769ABC transporter, ATP-binding protein. (604 aa)
GYO_1772YknY. (230 aa)
GYO_1779YkpA. (539 aa)
GYO_1881ABC transporter family protein. (264 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (329 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (446 aa)
hslUHeat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (467 aa)
fliIFlagellar protein export ATPase FliI. (427 aa)
GYO_2037DNA translocase ftsK; Belongs to the FtsK/SpoIIIE/SftA family. (786 aa)
GYO_1195ABC transporter. (232 aa)
ssuBSsuB; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system. (298 aa)
GYO_1137YgaD. (580 aa)
GYO_1100Transposase. (311 aa)
GYO_1090ABC transporter. (604 aa)
GYO_1089Multidrug ABC transporter ATP-binding protein. (573 aa)
GYO_1079Transcriptional regulator. (617 aa)
GYO_1014Ferrichrome transport ATP-binding protein FhuC. (266 aa)
GYO_1007YfmM. (518 aa)
GYO_1000ABC transporter, ATP-binding protein. (629 aa)
GYO_0870Tetratricopeptide repeat family. (835 aa)
GYO_0859YdiF. (642 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (446 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (546 aa)
ftsHConserved hypothetical protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (637 aa)
clpCNegative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family. (810 aa)
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (458 aa)
yveKCobalt import ATP-binding protein CbiO 1; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (281 aa)
GYO_0456Bacitracin transport ATP-binding protein BcrA. (307 aa)
GYO_0476ATP-binding transport protein NatA. (246 aa)
GYO_0489Zinc uptake system ATP-binding protein zurA. (231 aa)
GYO_0502Glycine betaine transport ATP-binding protein opuAA. (418 aa)
GYO_0553ABC transporter, ATP-binding protein. (242 aa)
GYO_0574YckI. (247 aa)
GYO_0589YclH. (226 aa)
GYO_0598YclP. (252 aa)
GYO_0669YdbJ. (308 aa)
GYO_0813Nucleotide binding protein ExpZ. (542 aa)
oppFOligopeptide transport ATP-binding protein OppF; Belongs to the ABC transporter superfamily. (305 aa)
oppDOligopeptide transport ATP-binding protein OppD; Belongs to the ABC transporter superfamily. (355 aa)
GYO_1441Oligopeptide transport ATP-binding protein AppF; Belongs to the ABC transporter superfamily. (329 aa)
GYO_1440Oligopeptide transport ATP-binding protein AppD; Belongs to the ABC transporter superfamily. (328 aa)
dnaCReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (454 aa)
GYO_4444Arginine utilization regulatory protein RocR. (462 aa)
GYO_4423ABC transporter, ATP-binding protein. (209 aa)
GYO_4371ABC transporter ATP-binding protein YxdL. (257 aa)
GYO_4356Putative amino-acid ABC transporter ATP-binding protein YtmN. (249 aa)
GYO_4285Multiple sugar-binding transport ATP-binding protein MsmK; Belongs to the ABC transporter superfamily. (365 aa)
cydDABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD. (567 aa)
GYO_4274ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC. (575 aa)
GYO_4267YxlF. (295 aa)
GYO_4131ABC transporter, ATP-binding protein. (215 aa)
GYO_4119YwhQ protein. (239 aa)
GYO_4102ABC transporter transmembrane region family protein. (574 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (427 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (473 aa)
urtDABC transporter. (249 aa)
urtEABC transporter. (233 aa)
rbsARibose transport ATP-binding protein RbsA; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (493 aa)
tagHTeichoic acids export ATP-binding protein TagH; Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system. (527 aa)
GYO_3903Bacitracin transport ATP-binding protein BcrA. (219 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (228 aa)
uvrAExcinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (957 aa)
GYO_3818Multidrug resistance ABC transporter ATP-binding and permease protein. (589 aa)
GYO_3804Bacitracin export ATP-binding protein BceA. (259 aa)
GYO_3741YvfR. (300 aa)
GYO_3706Glycine betaine/carnitine/choline transport ATP-binding protein opuCA. (379 aa)
GYO_3700Choline transport ATP-binding protein opuBA. (381 aa)
GYO_3695Conserved hypothetical protein. (614 aa)
GYO_3691Bacitracin transport ATP-binding protein BcrA. (238 aa)
GYO_3638Ferrichrome transport ATP-binding protein FhuC. (269 aa)
GYO_3636ABC transporter. (229 aa)
GYO_3623YvrA. (441 aa)
GYO_3597YusV. (273 aa)
metNYusC; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (341 aa)
sufCFeS assembly ATPase SufC. (261 aa)
GYO_3555Putative ABC transporter ATP-binding protein YcjV; Belongs to the ABC transporter superfamily. (367 aa)
GYO_3444ABC transporter. (510 aa)
GYO_3330Manganese transport system ATP-binding protein MntB. (250 aa)
ytlCABC transporter, ATP-binding sporulation protein YtlC. (260 aa)
GYO_3296YtrB. (292 aa)
GYO_3293YtrE. (231 aa)
GYO_3289Bacitracin export ATP-binding protein BceA. (253 aa)
GYO_3249ABC-type transporter ATP-binding protein EcsA. (236 aa)
GYO_3228YtpT; Belongs to the FtsK/SpoIIIE/SftA family. (1020 aa)
GYO_3148Primosomal protein DnaI. (311 aa)
clpXATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (420 aa)
lonBATP-dependent protease LonB. (552 aa)
lonATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (774 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (334 aa)
GYO_2992ATPase family associated with various cellular activities family protein. (422 aa)
recD2Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (798 aa)
GYO_2942Sigma-54 interaction domain family. (935 aa)
pstB-2Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (248 aa)
pstBPhosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (242 aa)
comGAComG operon protein 1. (356 aa)
spoIIIAAStage III sporulation protein AA. (307 aa)
GYO_2655Sigma-54 interaction domain family. (691 aa)
GYO_2641YqiZ. (240 aa)
GYO_2341YojN. (296 aa)
GYO_2230ABC-type MDR transporter, ATPase component. (312 aa)
spoVKStage V sporulation protein K. (322 aa)
recAProtein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (348 aa)
GYO_1298ABC-type transporter ATP-binding protein EcsA. (247 aa)
GYO_1281YhaQ. (298 aa)
GYO_1263ABC transporter, ATP-binding protein. (673 aa)
GYO_1262YheI. (585 aa)
GYO_1196YhcH. (305 aa)
Your Current Organism:
Bacillus subtilis spizizenii
NCBI taxonomy Id: 1052585
Other names: B. subtilis subsp. spizizenii TU-B-10, Bacillus subtilis subsp. spizizenii TU-B-10, Bacillus subtilis subsp. spizizenii str. TU-B-10, Bacillus subtilis subsp. spizizenii strain TU-B-10
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