STRINGSTRING
secE secE rpoB rpoB rpoC rpoC tuf tuf secY secY rpoA rpoA GYO_0252 GYO_0252 GYO_0331 GYO_0331 GYO_0383 GYO_0383 GYO_0468 GYO_0468 GYO_0492 GYO_0492 yceI yceI GYO_0500 GYO_0500 GYO_0511 GYO_0511 GYO_0600 GYO_0600 GYO_0642 GYO_0642 GYO_0643 GYO_0643 GYO_0676 GYO_0676 GYO_0707 GYO_0707 GYO_0715 GYO_0715 GYO_0719 GYO_0719 GYO_0720 GYO_0720 GYO_0721 GYO_0721 GYO_0722 GYO_0722 GYO_0750 GYO_0750 GYO_0751 GYO_0751 arsC arsC GYO_0773 GYO_0773 GYO_0790 GYO_0790 GYO_0809 GYO_0809 GYO_0811 GYO_0811 GYO_0824 GYO_0824 GYO_0838 GYO_0838 GYO_0879 GYO_0879 GYO_0914 GYO_0914 GYO_1003 GYO_1003 GYO_1012 GYO_1012 GYO_1052 GYO_1052 GYO_1055 GYO_1055 GYO_1058 GYO_1058 GYO_1077 GYO_1077 GYO_1085 GYO_1085 GYO_1089 GYO_1089 GYO_1090 GYO_1090 GYO_1094 GYO_1094 GYO_1109 GYO_1109 GYO_1122 GYO_1122 GYO_1137 GYO_1137 GYO_1140 GYO_1140 ssuD ssuD GYO_1190 GYO_1190 GYO_1262 GYO_1262 GYO_1263 GYO_1263 GYO_1362 GYO_1362 yitG yitG GYO_1422 GYO_1422 GYO_1442 GYO_1442 GYO_1443 GYO_1443 GYO_1444 GYO_1444 oppB oppB oppC oppC GYO_1452 GYO_1452 GYO_1461 GYO_1461 GYO_1556 GYO_1556 GYO_1597 GYO_1597 GYO_1612 GYO_1612 GYO_1613 GYO_1613 GYO_1739 GYO_1739 ykuU ykuU GYO_1768 GYO_1768 GYO_1769 GYO_1769 GYO_1799 GYO_1799 rpoZ rpoZ GYO_2039 GYO_2039 GYO_2119 GYO_2119 GYO_2169 GYO_2169 GYO_2232 GYO_2232 GYO_2248 GYO_2248 GYO_2335 GYO_2335 sucB sucB sodC sodC msrA msrA ndk ndk GYO_2527 GYO_2527 resA resA ribD ribD GYO_2616 GYO_2616 GYO_2646 GYO_2646 GYO_2648 GYO_2648 pstS pstS GYO_2767 GYO_2767 cwlH cwlH GYO_2881 GYO_2881 GYO_2904 GYO_2904 secDF secDF trx trx GYO_3154 GYO_3154 GYO_3184 GYO_3184 ytgI ytgI GYO_3224 GYO_3224 GYO_3231 GYO_3231 GYO_3286 GYO_3286 GYO_3391 GYO_3391 GYO_3429 GYO_3429 GYO_3437 GYO_3437 GYO_3481 GYO_3481 GYO_3503 GYO_3503 GYO_3543 GYO_3543 GYO_3592 GYO_3592 GYO_3621 GYO_3621 secG secG GYO_3695 GYO_3695 GYO_3721 GYO_3721 GYO_3723 GYO_3723 trxB trxB GYO_3818 GYO_3818 GYO_3832 GYO_3832 GYO_3847 GYO_3847 GYO_3861 GYO_3861 secA secA GYO_3942 GYO_3942 GYO_3967 GYO_3967 GYO_4009 GYO_4009 GYO_4012 GYO_4012 GYO_4069 GYO_4069 GYO_4102 GYO_4102 GYO_4156 GYO_4156 GYO_4161 GYO_4161 GYO_4200 GYO_4200 GYO_4204 GYO_4204 GYO_4265 GYO_4265 GYO_4360 GYO_4360 GYO_4378 GYO_4378 GYO_4388 GYO_4388 ahpC ahpC GYO_4482 GYO_4482 GYO_4498 GYO_4498
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
secEPreprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (59 aa)
rpoBDNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1193 aa)
rpoCDNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1199 aa)
tufTranslation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (396 aa)
secYPreprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (431 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (314 aa)
GYO_0252N-acetylmuramoyl-L-alanine amidase XlyB. (324 aa)
GYO_0331N-acetylmuramoyl-L-alanine amidase XlyB. (324 aa)
GYO_0383YbcL. (390 aa)
GYO_0468Lincomycin resistance protein LmrB; Belongs to the major facilitator superfamily. (477 aa)
GYO_0492YceB. (348 aa)
yceIMajor facilitator family transporter. (400 aa)
GYO_0500Conserved hypothetical protein. (57 aa)
GYO_0511Multidrug transporter; Belongs to the major facilitator superfamily. (512 aa)
GYO_0600YcnB; Belongs to the major facilitator superfamily. (472 aa)
GYO_0642YdzA. (96 aa)
GYO_0643HTH-type transcriptional regulator lrpC. (144 aa)
GYO_0676YdbP; Belongs to the thioredoxin family. (106 aa)
GYO_0707Major facilitator superfamily. (413 aa)
GYO_0715Transcriptional regulator, Lrp/AsnC family. (147 aa)
GYO_0719Bacterial luciferase family protein. (333 aa)
GYO_0720HTH-type transcriptional regulator LrpA. (173 aa)
GYO_0721YddR. (254 aa)
GYO_0722Tetracycline resistance protein. (436 aa)
GYO_0750Metallo-beta-lactamase superfamily, putative. (253 aa)
GYO_0751HTH-type transcriptional regulator LrpA. (136 aa)
arsCArsenate reductase; Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)]. (139 aa)
GYO_0773Alkylhydroperoxidase AhpD core; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (147 aa)
GYO_0790YdfQ. (112 aa)
GYO_0809Sugar transporter family protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (447 aa)
GYO_0811Quinolone resistance NorA protein. (400 aa)
GYO_0824YdgK. (402 aa)
GYO_0838Transporter, major facilitator superfamily. (388 aa)
GYO_0879Major myo-inositol transporter IolT; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (473 aa)
GYO_0914Transcriptional regulator, asnc family. (140 aa)
GYO_1003Multidrug efflux protein YfmO. (396 aa)
GYO_1012Transporter, major facilitator family. (406 aa)
GYO_1052Transporter, major facilitator family. (395 aa)
GYO_1055YfkJ; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (156 aa)
GYO_1058Major Facilitator Superfamily protein. (391 aa)
GYO_1077Dihydrolipoyllysine-residue acetyltransferase component of acetoincleaving system. (398 aa)
GYO_1085Conserved hypothetical protein; Belongs to the WXG100 family. (104 aa)
GYO_1089Multidrug ABC transporter ATP-binding protein. (573 aa)
GYO_1090ABC transporter. (604 aa)
GYO_1094Major myo-inositol transporter IolT; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (482 aa)
GYO_1109YfiU. (518 aa)
GYO_1122YfhI. (397 aa)
GYO_1137YgaD. (580 aa)
GYO_1140YgaF. (157 aa)
ssuDAlkanesulfonate monooxygenase; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family. (380 aa)
GYO_1190YhcA; Belongs to the major facilitator superfamily. (532 aa)
GYO_1262YheI. (585 aa)
GYO_1263ABC transporter, ATP-binding protein. (673 aa)
GYO_1362Peptide permease. (400 aa)
yitGSporulation protein YitG. (422 aa)
GYO_1422Multidrug resistance protein B. (172 aa)
GYO_1442Oligopeptide-binding protein AppA. (542 aa)
GYO_1443Oligopeptide transport system permease protein AppB. (316 aa)
GYO_1444Oligopeptide transport system permease protein AppC. (304 aa)
oppBOligopeptide transport system permease protein OppB. (311 aa)
oppCOligopeptide transport system permease protein OppC. (305 aa)
GYO_1452Membrane protein, putative. (374 aa)
GYO_1461YjbI. (132 aa)
GYO_1556N-acetylmuramoyl-L-alanine amidase XlyB. (317 aa)
GYO_1597N-acetylmuramoyl-L-alanine amidase XlyA. (297 aa)
GYO_1612Dipeptide transport system permease protein DppB. (308 aa)
GYO_1613Dipeptide transport system permease protein DppC. (320 aa)
GYO_1739YkuC protein. (430 aa)
ykuUPeroxiredoxin. (180 aa)
GYO_1768ABC transporter, ATP-binding protein. (594 aa)
GYO_1769ABC transporter, ATP-binding protein. (604 aa)
GYO_1799Dihydrolipoyllysine-residue acetyltransferase component of pyruvatedehydrogenase complex. (442 aa)
rpoZDNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (67 aa)
GYO_2039Multidrug resistance protein. (410 aa)
GYO_2119Arabinose-proton symporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (468 aa)
GYO_2169YneN. (170 aa)
GYO_2232Alpha-ketoglutarate permease. (414 aa)
GYO_2248Necrosis and ethylene inducing protein. (238 aa)
GYO_2335Putative superoxide dismutase. (281 aa)
sucB2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (417 aa)
sodCCopper/zinc superoxide dismutase. (196 aa)
msrAmethionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (177 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (148 aa)
GYO_2527YpdA. (324 aa)
resAThiol-disulfide oxidoreductase ResA; Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. (179 aa)
ribDRiboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (361 aa)
GYO_2616MFS-type transporter ydeE. (410 aa)
GYO_2646Multidrug resistance protein 1. (389 aa)
GYO_2648Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex. (427 aa)
pstSPstS. (300 aa)
GYO_2767Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (202 aa)
cwlHSporulation-specific N-acetylmuramoyl-L-alanine amidase CwlH. (250 aa)
GYO_2881Metallo-beta-lactamase superfamily, putative. (253 aa)
GYO_2904Multidrug resistance protein 2. (400 aa)
secDFSecDF protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (737 aa)
trxThioredoxin; Belongs to the thioredoxin family. (104 aa)
GYO_3154Inner membrane transport protein ydhP. (396 aa)
GYO_3184Metal-dependent hydrolase YtkL; Belongs to the UPF0173 family. (227 aa)
ytgIPutative thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (167 aa)
GYO_3224YtxJ. (108 aa)
GYO_3231YtpP. (107 aa)
GYO_3286Major Facilitator Superfamily protein. (397 aa)
GYO_3391Transporter, major facilitator family. (511 aa)
GYO_3429Transcriptional regulator. (164 aa)
GYO_3437Multidrug resistance protein MdtG. (392 aa)
GYO_3481Conserved hypothetical protein; Belongs to the WXG100 family. (97 aa)
GYO_3503YumC. (332 aa)
GYO_3543Thiol-disulfide oxidoreductase ResA. (179 aa)
GYO_3592Multidrug resistance protein B; Belongs to the major facilitator superfamily. (538 aa)
GYO_3621YvqJ. (422 aa)
secGPutative protein-export membrane protein SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (76 aa)
GYO_3695Conserved hypothetical protein. (614 aa)
GYO_3721Arabinose-proton symporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (464 aa)
GYO_3723YvbT2. (336 aa)
trxBThioredoxin-disulfide reductase. (316 aa)
GYO_3818Multidrug resistance ABC transporter ATP-binding and permease protein. (589 aa)
GYO_3832Pectate lyase. (194 aa)
GYO_3847YvmA. (403 aa)
GYO_3861Transporter, major facilitator family. (444 aa)
secAPreprotein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (841 aa)
GYO_3942Sugar transporter family protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (457 aa)
GYO_3967YwrC. (158 aa)
GYO_4009YwoG. (396 aa)
GYO_4012YwoD. (452 aa)
GYO_4069YwlE; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (150 aa)
GYO_4102ABC transporter transmembrane region family protein. (574 aa)
GYO_4156Putative bacilysin exporter BacE. (375 aa)
GYO_4161Transporter, major facilitator family. (412 aa)
GYO_4200YwcH. (333 aa)
GYO_4204Acetyltransferase, gnat family. (381 aa)
GYO_4265YxlH. (400 aa)
GYO_4360Nitrilotriacetate monooxygenase component A. (441 aa)
GYO_4378Minor myo-inositol transporter IolF. (438 aa)
GYO_4388Arabinose-proton symporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (461 aa)
ahpCPeroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)
GYO_4482Major facilitator family transporter. (399 aa)
GYO_4498Major facilitator superfamily. (451 aa)
Your Current Organism:
Bacillus subtilis spizizenii
NCBI taxonomy Id: 1052585
Other names: B. subtilis subsp. spizizenii TU-B-10, Bacillus subtilis subsp. spizizenii TU-B-10, Bacillus subtilis subsp. spizizenii str. TU-B-10, Bacillus subtilis subsp. spizizenii strain TU-B-10
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