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GYO_0014 GYO_0014 GYO_0359 GYO_0359 ddl ddl murF murF GYO_1306 GYO_1306 GYO_1732 GYO_1732 pbpB pbpB spoVD spoVD murE murE mraY mraY murD murD murG murG murB murB uppS uppS GYO_2204 GYO_2204 GYO_2367 GYO_2367 GYO_2458 GYO_2458 GYO_2552 GYO_2552 GYO_2765 GYO_2765 GYO_2797 GYO_2797 murC murC uppP uppP GYO_3438 GYO_3438 GYO_4017 GYO_4017 murA murA murA-2 murA-2 GYO_4135 GYO_4135
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GYO_0014D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (443 aa)
GYO_0359Beta-lactamase. (441 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (361 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (457 aa)
GYO_1306Penicillin-binding protein, 1A family. (714 aa)
GYO_1732Penicillin-binding Protein dimerization domain family. (704 aa)
pbpBPenicillin-binding Protein dimerization domain family. (713 aa)
spoVDStage V sporulation protein D. (646 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (447 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (324 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (451 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (363 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (303 aa)
uppSUndecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (260 aa)
GYO_2204D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase. (491 aa)
GYO_2367YokZ. (273 aa)
GYO_2458Penicillin-binding protein, 1A family, putative. (913 aa)
GYO_2552Sporulation-specific penicillin-binding protein 5*; Belongs to the peptidase S11 family. (382 aa)
GYO_2765Penicillin-binding Protein dimerization domain family. (716 aa)
GYO_2797Diacylglycerol kinase. (123 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (432 aa)
uppPUndecaprenol kinase, putative; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (276 aa)
GYO_3438Transglycosylase domain protein. (622 aa)
GYO_4017YwoA. (193 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (436 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (429 aa)
GYO_4135Penicillin-binding protein 1F. (691 aa)
Your Current Organism:
Bacillus subtilis spizizenii
NCBI taxonomy Id: 1052585
Other names: B. subtilis subsp. spizizenii TU-B-10, Bacillus subtilis subsp. spizizenii TU-B-10, Bacillus subtilis subsp. spizizenii str. TU-B-10, Bacillus subtilis subsp. spizizenii strain TU-B-10
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