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gabT gabT GYO_1078 GYO_1078 GYO_1333 GYO_1333 GYO_1337 GYO_1337 GYO_1800 GYO_1800 sucC sucC sucD sucD yngXX yngXX yngH yngH GYO_2380 GYO_2380 GYO_2381 GYO_2381 mgsA mgsA GYO_2637 GYO_2637 mce mce GYO_2648 GYO_2648 GYO_2649 GYO_2649 GYO_2650 GYO_2650 GYO_2651 GYO_2651 yqiQ yqiQ mmgE mmgE mmgA mmgA accC accC accB accB GYO_3155 GYO_3155 accA accA accD accD ackA ackA GYO_3202 GYO_3202 GYO_3216 GYO_3216 GYO_3651 GYO_3651 pta pta mmsA mmsA ldh ldh
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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gabT4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (436 aa)
GYO_1078Dihydrolipoamide dehydrogenase. (458 aa)
GYO_1333Protein YhdH. (330 aa)
GYO_1337acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (364 aa)
GYO_1800Dihydrolipoamide dehydrogenase. (470 aa)
sucCsuccinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (385 aa)
sucDsuccinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa)
yngXXPutative glutaconyl-CoA decarboxylase activity YngXX. (73 aa)
yngHPutative acetyl-CoA and biotin carboxylase YngH. (442 aa)
GYO_23803-oxoadipate CoA-transferase subunit B. (217 aa)
GYO_2381Acetate CoA-transferase alpha subunit. (229 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (137 aa)
GYO_2637propionyl-CoA carboxylase. (509 aa)
mcemethylmalonyl-CoA epimerase. (140 aa)
GYO_2648Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex. (427 aa)
GYO_26492-oxoisovalerate dehydrogenase beta subunit. (327 aa)
GYO_26502-oxoisovalerate dehydrogenase alpha subunit. (330 aa)
GYO_2651Dihydrolipoamide dehydrogenase. (474 aa)
yqiQPutative methylisocitrate lyase YqiQ; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (301 aa)
mmgE2-methylcitrate dehydratase. (472 aa)
mmgAacetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
accCacetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
accBacetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (160 aa)
GYO_3155Prostaglandin F synthase. (280 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa)
GYO_3202YtcI. (529 aa)
GYO_3216AMP-binding enzyme, putative. (572 aa)
GYO_3651YvgN. (260 aa)
ptaPhosphate acetyltransferase. (323 aa)
mmsAMethylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. (487 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (321 aa)
Your Current Organism:
Bacillus subtilis spizizenii
NCBI taxonomy Id: 1052585
Other names: B. subtilis subsp. spizizenii TU-B-10, Bacillus subtilis subsp. spizizenii TU-B-10, Bacillus subtilis subsp. spizizenii str. TU-B-10, Bacillus subtilis subsp. spizizenii strain TU-B-10
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