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| | talC | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (212 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa) |
| | cysK | Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. (308 aa) |
| | cysE | Serine O-acetyltransferase. (217 aa) |
| | GYO_0485 | Glucose 1-dehydrogenase. (258 aa) |
| | hxlB | 6-phospho 3-hexuloisomerase. (185 aa) |
| | hxlA | 3-hexulose-6-phosphate synthase. (210 aa) |
| | GYO_0610 | Glucose 1-dehydrogenase. (261 aa) |
| | GYO_1077 | Dihydrolipoyllysine-residue acetyltransferase component of acetoincleaving system. (398 aa) |
| | GYO_1078 | Dihydrolipoamide dehydrogenase. (458 aa) |
| | katA | Catalase; Belongs to the catalase family. (483 aa) |
| | GYO_1232 | Citrate synthase 1; Belongs to the citrate synthase family. (366 aa) |
| | serC | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (359 aa) |
| | GYO_1337 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (364 aa) |
| | GYO_1523 | Formate dehydrogenase, alpha subunit, putative. (985 aa) |
| | GYO_1620 | YkgB. (348 aa) |
| | pdhA | Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (371 aa) |
| | GYO_1798 | Pyruvate dehydrogenase E1 component subunit beta. (325 aa) |
| | GYO_1799 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvatedehydrogenase complex. (442 aa) |
| | GYO_1800 | Dihydrolipoamide dehydrogenase. (470 aa) |
| | pyc | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1148 aa) |
| | rpe | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (217 aa) |
| | sdaAB | L-serine dehydratase, iron-sulfur-dependent, beta subunit. (220 aa) |
| | sdaAA | L-serine dehydratase, iron-sulfur-dependent, alpha subunit. (300 aa) |
| | sucC | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (385 aa) |
| | sucD | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa) |
| | tkt | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (667 aa) |
| | acnA | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (909 aa) |
| | yngXX | Putative glutaconyl-CoA decarboxylase activity YngXX. (73 aa) |
| | yngH | Putative acetyl-CoA and biotin carboxylase YngH. (442 aa) |
| | GYO_2234 | Putative D-isomer specific 2-hydroxyacid dehydrogenase. (333 aa) |
| | sucB | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (417 aa) |
| | sucA | 2-oxoglutarate dehydrogenase, E1 component; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). (944 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (422 aa) |
| | GYO_2435 | Khg/kdpg aldolase. (196 aa) |
| | GYO_2436 | 2-dehydro-3-deoxygluconokinase. (324 aa) |
| | serA | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (525 aa) |
| | GYO_2591 | Putative NAD-dependent malic enzyme 1. (439 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (489 aa) |
| | GYO_2631 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (469 aa) |
| | GYO_2637 | propionyl-CoA carboxylase. (509 aa) |
| | mce | methylmalonyl-CoA epimerase. (140 aa) |
| | GYO_2651 | Dihydrolipoamide dehydrogenase. (474 aa) |
| | mmgD | Citrate synthase 3; Belongs to the citrate synthase family. (372 aa) |
| | mmgB | 3-hydroxybutyryl-CoA dehydrogenase. (287 aa) |
| | mmgA | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | folD | FolD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (283 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa) |
| | accB | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (160 aa) |
| | gcvPB | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (488 aa) |
| | gcvPA | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (448 aa) |
| | gcvT | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (362 aa) |
| | GYO_2749 | Glucokinase. (321 aa) |
| | GYO_2843 | 6-phosphogluconate dehydrogenase. (297 aa) |
| | adhB | S-(hydroxymethyl)glutathione dehydrogenase. (378 aa) |
| | GYO_2962 | Formate dehydrogenase, alpha subunit, putative. (982 aa) |
| | GYO_3089 | Succinate dehydrogenase iron-sulfur subunit. (253 aa) |
| | GYO_3090 | Succinate dehydrogenase flavoprotein subunit. (586 aa) |
| | GYO_3091 | Succinate dehydrogenase cytochrome b558 subunit. (202 aa) |
| | GYO_3152 | Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (340 aa) |
| | mdh | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa) |
| | icd | Isocitrate dehydrogenase, NADP-dependent. (423 aa) |
| | GYO_3166 | Citrate synthase 2; Belongs to the citrate synthase family. (372 aa) |
| | pyk | Pyruvate kinase; Belongs to the pyruvate kinase family. (558 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa) |
| | GYO_3175 | YtsJ. (410 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa) |
| | GYO_3202 | YtcI. (529 aa) |
| | GYO_3216 | AMP-binding enzyme, putative. (572 aa) |
| | GYO_3236 | Putative NAD-dependent malic enzyme 3. (566 aa) |
| | GYO_3245 | Putative cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (527 aa) |
| | pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (450 aa) |
| | gcvH | Glycine cleavage system H protein; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family. (127 aa) |
| | GYO_3586 | 3-hydroxyacyl-CoA dehydrogenase, C- domain family. (789 aa) |
| | fumC | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (511 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (253 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (394 aa) |
| | GYO_3718 | Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa) |
| | rpiB | Ribose 5-phosphate isomerase B. (149 aa) |
| | GYO_4081 | Putative NAD-dependent malic enzyme 3. (565 aa) |
| | glpX | Fructose-1,6-bisphosphatase, class II. (321 aa) |
| | fba | Fructose-1,6-bisphosphate aldolase, class II. (285 aa) |
| | pta | Phosphate acetyltransferase. (323 aa) |
| | katX | Catalase; Belongs to the catalase family. (547 aa) |
| | GYO_4310 | Catalase-related family; Serves to protect cells from the toxic effects of hydrogen peroxide. (686 aa) |
| | mmsA | Methylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. (487 aa) |
| | gntK | Gluconate kinase; Belongs to the FGGY kinase family. (513 aa) |
| | GYO_4411 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa) |
| | GYO_4433 | Formaldehyde dehydrogenase, glutathione-independent. (403 aa) |
