STRINGSTRING
GYO_0635 GYO_0635 GYO_1133 GYO_1133 fabH fabH GYO_1325 GYO_1325 GYO_1337 GYO_1337 GYO_1338 GYO_1338 fabH-2 fabH-2 fabF fabF GYO_1477 GYO_1477 GYO_1940 GYO_1940 fabG fabG GYO_2042 GYO_2042 yngXX yngXX yngH yngH GYO_2203 GYO_2203 GYO_2223 GYO_2223 mmgA mmgA accC accC accB accB GYO_3101 GYO_3101 GYO_3103 GYO_3103 accA accA accD accD GYO_3185 GYO_3185 GYO_3585 GYO_3585 GYO_3586 GYO_3586 GYO_3594 GYO_3594 GYO_3675 GYO_3675 fabZ fabZ
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GYO_0635AMP-dependent synthetase and ligase. (503 aa)
GYO_11333-oxoacyl-[acyl-carrier-protein] reductase. (250 aa)
fabH3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 1; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (325 aa)
GYO_1325long-chain-fatty-acid--CoA ligase. (529 aa)
GYO_1337acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (364 aa)
GYO_1338acyl-CoA synthase. (481 aa)
fabH-23-oxoacyl-[acyl-carrier-protein] synthase 3 protein 1; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (312 aa)
fabF3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (413 aa)
GYO_1477Enoyl-[acyl-carrier-protein] reductase. (258 aa)
GYO_1940Malonyl CoA-acyl carrier protein transacylase. (317 aa)
fabG3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
GYO_2042Short chain dehydrogenase. (242 aa)
yngXXPutative glutaconyl-CoA decarboxylase activity YngXX. (73 aa)
yngHPutative acetyl-CoA and biotin carboxylase YngH. (442 aa)
GYO_2203Malonyl CoA-acyl carrier protein transacylase. (399 aa)
GYO_2223Short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (238 aa)
mmgAacetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
accCacetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
accBacetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (160 aa)
GYO_3101enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
GYO_3103long-chain-fatty-acid--CoA ligase. (559 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa)
GYO_3185Short chain dehydrogenase. (255 aa)
GYO_3585acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
GYO_35863-hydroxyacyl-CoA dehydrogenase, C- domain family. (789 aa)
GYO_35943-oxoacyl-[acyl-carrier-protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
GYO_36753-oxoacyl-[acyl-carrier-protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (264 aa)
fabZBeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (141 aa)
Your Current Organism:
Bacillus subtilis spizizenii
NCBI taxonomy Id: 1052585
Other names: B. subtilis subsp. spizizenii TU-B-10, Bacillus subtilis subsp. spizizenii TU-B-10, Bacillus subtilis subsp. spizizenii str. TU-B-10, Bacillus subtilis subsp. spizizenii strain TU-B-10
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