(124 nodes) Glycine, serine and threonine metabolism network (Aspergillus awamori)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AAWM_10978	CinA-like protein. (739 aa)
	AAWM_10976	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (534 aa)
	AAWM_06753	Catabolic L-serine/threonine dehydratase. (443 aa)
	AAWM_06724	Threonine dehydratase. (565 aa)
	AAWM_00903	Low-specificity L-threonine aldolase. (373 aa)
	AAWM_01005	Versicolorin B synthase. (624 aa)
	AAWM_01006	Uncharacterized protein YdcJ. (465 aa)
	AAWM_01047	Amine oxidase. (690 aa)
	AAWM_01176	L-saccharopine oxidase. (458 aa)
	AAWM_01232	Amine oxidase. (493 aa)
	AAWM_01200	Uncharacterized protein HI_1014. (317 aa)
	AAWM_01316	Homoserine dehydrogenase. (370 aa)
	AAWM_01687	Tryptophan synthase. (723 aa)
	AAWM_01868	PNPLA domain-containing protein. (362 aa)
	AAWM_01781	Phosphoserine aminotransferase. (1344 aa)
	AAWM_01807	Choline dehydrogenase, mitochondrial. (608 aa)
	AAWM_02026	D-amino-acid oxidase. (350 aa)
	AAWM_02169	D-amino-acid oxidase. (354 aa)
	AAWM_02183	DASH complex subunit dad4. (67 aa)
	AAWM_02335	L-pipecolate oxidase. (438 aa)
	AAWM_02339	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1060 aa)
	AAWM_02352	Uncharacterized kinase mug58. (322 aa)
	AAWM_02227	Acid phosphatase. (299 aa)
	AAWM_02656	Serine racemase. (377 aa)
	AAWM_02831	Amine oxidase; Belongs to the copper/topaquinone oxidase family. (1422 aa)
	AAWM_02968	85/88 kDa calcium-independent phospholipase A2. (1176 aa)
	AAWM_02920	Probable oxidoreductase OrdL. (462 aa)
	AAWM_03125	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (341 aa)
	AAWM_03321	Calcium-independent phospholipase A2-gamma. (1089 aa)
	AAWM_03336	Calcium-independent phospholipase A2-gamma. (610 aa)
	AAWM_03348	Protein kinase domain-containing protein. (234 aa)
	AAWM_03429	L-pipecolate oxidase. (437 aa)
	AAWM_03453	Glucose oxidase. (588 aa)
	AAWM_03551	Intermediate cleaving peptidase 55. (498 aa)
	AAWM_07024	Oxygen-dependent choline dehydrogenase. (593 aa)
	AAWM_07132	Probable Xaa-Pro aminopeptidase P; Belongs to the peptidase M24B family. (614 aa)
	AAWM_07366	Phospholipase A I. (571 aa)
	AAWM_07473	Amine oxidase. (684 aa)
	AAWM_07580	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (649 aa)
	AAWM_07517	Probable oxidoreductase OrdL. (464 aa)
	AAWM_07641	Aspartokinase. (525 aa)
	AAWM_07671	NAD/NADP-dependent betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (498 aa)
	AAWM_07647	D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (474 aa)
	AAWM_07697	Cystathionine gamma-lyase. (409 aa)
	AAWM_07888	Sedoheptulose 1,7-bisphosphatase. (234 aa)
	AAWM_07622	Homoserine kinase. (354 aa)
	AAWM_07907	Oxygen-dependent choline dehydrogenase. (629 aa)
	AAWM_08131	Threonine synthase. (534 aa)
	AAWM_08027	L-pipecolate oxidase. (441 aa)
	AAWM_08133	Tryptophan synthase. (688 aa)
	AAWM_08099	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (471 aa)
	AAWM_08097	2,3-bisphosphoglycerate-independent phosphoglycerate mutase. (520 aa)
	AAWM_03762	Probable phosphoserine phosphatase. (469 aa)
	AAWM_03738	Probable aspartate-semialdehyde dehydrogenase. (363 aa)
	AAWM_00494	Dihydrolipoyl dehydrogenase. (514 aa)
	AAWM_00464	Amine oxidase. (665 aa)
	AAWM_00428	L-saccharopine oxidase. (443 aa)
	AAWM_00373	L-saccharopine oxidase. (435 aa)
	AAWM_00073	Low specificity L-threonine aldolase. (351 aa)
	AAWM_00058	Glucose oxidase. (596 aa)
	AAWM_08149	Trichothecene 3-O-acetyltransferase. (447 aa)
	AAWM_08258	NADP-dependent 3-hydroxy acid dehydrogenase. (861 aa)
	AAWM_08369	Uncharacterized protein. (738 aa)
	AAWM_08579	Alcohol dehydrogenase 1. (679 aa)
	AAWM_08606	Alpha-L-arabinofuranosidase axhA. (332 aa)
	AAWM_08617	Amine oxidase. (668 aa)
	AAWM_08859	Glucose oxidase. (605 aa)
	AAWM_08997	Probable Xaa-Pro aminopeptidase An01g13040. (491 aa)
	AAWM_09059	Uncharacterized protein HI_1014. (323 aa)
	AAWM_09263	CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (232 aa)
	AAWM_09769	D-amino-acid oxidase. (369 aa)
	AAWM_09774	NADP-dependent 3-hydroxy acid dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (270 aa)
	AAWM_09824	Amine oxidase. (480 aa)
	AAWM_10027	Amine oxidase. (688 aa)
	AAWM_10127	L-sorbose 1-dehydrogenase. (600 aa)
	AAWM_10346	L-pipecolate oxidase. (484 aa)
	AAWM_10494	Uncharacterized protein. (317 aa)
	AAWM_06248	L-pipecolate oxidase. (454 aa)
	AAWM_06175	D-amino-acid oxidase. (331 aa)
	AAWM_06077	Protein kinase domain-containing protein. (227 aa)
	AAWM_05867	Versicolorin B synthase. (673 aa)
	AAWM_05810	Calcium-independent phospholipase A2-gamma. (328 aa)
	AAWM_05791	Pyranose dehydrogenase 3. (617 aa)
	AAWM_05686	Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (343 aa)
	AAWM_05540	Dimethylglycine oxidase. (398 aa)
	AAWM_05420	Probable aminomethyltransferase, mitochondrial. (531 aa)
	AAWM_05292	L-pipecolate oxidase. (428 aa)
	AAWM_05267	Alanine--glyoxylate aminotransferase 1. (521 aa)
	AAWM_05046	Tryptophan synthase. (448 aa)
	AAWM_04794	Versicolorin B synthase. (612 aa)
	AAWM_04757	Versicolorin B synthase. (637 aa)
	AAWM_04692	Versicolorin B synthase. (605 aa)
	AAWM_04630	L-pipecolate oxidase. (974 aa)
	AAWM_04555	Uncharacterized kinase mug58. (309 aa)
	AAWM_04511	L-sorbose 1-dehydrogenase. (602 aa)
	AAWM_04462	Sedoheptulose 1,7-bisphosphatase. (208 aa)
	AAWM_04382	Probable pyridine nucleotide-disulfide oxidoreductase RclA. (800 aa)
	AAWM_04340	Pyranose dehydrogenase 3. (620 aa)
	AAWM_04329	Amine oxidase. (597 aa)
	AAWM_04244	Versicolorin B synthase. (618 aa)
	AAWM_04276	Choline dehydrogenase, mitochondrial. (668 aa)
	AAWM_04124	Amine oxidase. (497 aa)
	AAWM_04135	Glucose oxidase. (655 aa)
	AAWM_04042	Trichothecene 3-O-acetyltransferase. (466 aa)
	AAWM_04049	Uncharacterized protein. (633 aa)
	AAWM_06249	Putative dioxygenase subunit alpha YeaW. (1172 aa)
	AAWM_06400	Uncharacterized transcriptional regulatory protein PB1A11.04c. (678 aa)
	AAWM_06586	Uncharacterized protein. (97 aa)
	AAWM_10961	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (532 aa)
	AAWM_10950	Probable Xaa-Pro aminopeptidase pepP. (466 aa)
	AAWM_11102	Arginine N-methyltransferase 2; S-adenosyl-L-methionine-dependent protein-arginine N- methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12. (434 aa)
	AAWM_11083	Oxygen-dependent choline dehydrogenase. (508 aa)
	AAWM_11162	Calcium-independent phospholipase A2-gamma. (1078 aa)
	AAWM_11202	Calcium-independent phospholipase A2-gamma. (406 aa)
	AAWM_11140	Amine oxidase. (461 aa)
	AAWM_10504	Uncharacterized protein. (226 aa)
	AAWM_10514	Calcium-independent phospholipase A2-gamma. (1090 aa)
	AAWM_10586	Versicolorin B synthase. (638 aa)
	AAWM_10686	Low-specificity L-threonine aldolase. (367 aa)
	AAWM_10627	Probable oxidoreductase OrdL. (454 aa)
	AAWM_10726	Dimethylglycine oxidase. (852 aa)
	AAWM_10677	Uncharacterized protein. (251 aa)
	AAWM_10694	Versicolorin B synthase. (638 aa)
	AAWM_10655	Uncharacterized GMC-type oxidoreductase Mb1310. (579 aa)

Your Current Organism:

Aspergillus awamori

NCBI taxonomy Id: 105351
Other names: A. awamori, ATCC 16877, Aspergillus awamorii, Aspergillus niger var. awamori, Aspergillus niger var. awamorii, CBS 557.65, ITEM 4509

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAWM_00058	AAWM_02026	A0A401KCY7	A0A401KIT3	Glucose oxidase.	D-amino-acid oxidase.	0.440
AAWM_00058	AAWM_07671	A0A401KCY7	A0A401KZP5	Glucose oxidase.	NAD/NADP-dependent betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.710
AAWM_00058	AAWM_09769	A0A401KCY7	A0A401L5S8	Glucose oxidase.	D-amino-acid oxidase.	0.440
AAWM_00073	AAWM_00494	A0A401KD14	A0A401KEG2	Low specificity L-threonine aldolase.	Dihydrolipoyl dehydrogenase.	0.584
AAWM_00073	AAWM_01200	A0A401KD14	A0A401KGL9	Low specificity L-threonine aldolase.	Uncharacterized protein HI_1014.	0.469
AAWM_00073	AAWM_02183	A0A401KD14	A0A401KIX2	Low specificity L-threonine aldolase.	DASH complex subunit dad4.	0.564
AAWM_00073	AAWM_02339	A0A401KD14	A0A401KJE2	Low specificity L-threonine aldolase.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	0.750
AAWM_00073	AAWM_02656	A0A401KD14	A0A401KKK7	Low specificity L-threonine aldolase.	Serine racemase.	0.693
AAWM_00073	AAWM_02920	A0A401KD14	A0A401KLE1	Low specificity L-threonine aldolase.	Probable oxidoreductase OrdL.	0.564
AAWM_00073	AAWM_03762	A0A401KD14	A0A401KNQ1	Low specificity L-threonine aldolase.	Probable phosphoserine phosphatase.	0.712
AAWM_00073	AAWM_04382	A0A401KD14	A0A401KQH3	Low specificity L-threonine aldolase.	Probable pyridine nucleotide-disulfide oxidoreductase RclA.	0.584
AAWM_00073	AAWM_05267	A0A401KD14	A0A401KSW1	Low specificity L-threonine aldolase.	Alanine--glyoxylate aminotransferase 1.	0.763
AAWM_00073	AAWM_05420	A0A401KD14	A0A401KTG3	Low specificity L-threonine aldolase.	Probable aminomethyltransferase, mitochondrial.	0.621
AAWM_00073	AAWM_05540	A0A401KD14	A0A401KTT7	Low specificity L-threonine aldolase.	Dimethylglycine oxidase.	0.564
AAWM_00073	AAWM_06724	A0A401KD14	A0A401KX47	Low specificity L-threonine aldolase.	Threonine dehydratase.	0.713
AAWM_00073	AAWM_06753	A0A401KD14	A0A401KX40	Low specificity L-threonine aldolase.	Catabolic L-serine/threonine dehydratase.	0.713
AAWM_00073	AAWM_07517	A0A401KD14	A0A401KZK0	Low specificity L-threonine aldolase.	Probable oxidoreductase OrdL.	0.564
AAWM_00073	AAWM_07580	A0A401KD14	A0A401KZE6	Low specificity L-threonine aldolase.	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.	0.659
AAWM_00073	AAWM_07622	A0A401KD14	A0A401L084	Low specificity L-threonine aldolase.	Homoserine kinase.	0.615
AAWM_00073	AAWM_08099	A0A401KD14	A0A401L169	Low specificity L-threonine aldolase.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.738

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