25 items (Cavenderia fasciculata) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Predicted Interactions

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Your Input:
	DFA_01846	FAD_binding_3 domain-containing protein. (293 aa)
	coq3	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (346 aa)
	DFA_01711	FAD-binding monooxygenase. (630 aa)
	DFA_01058	Sepiapterin reductase. (268 aa)
	pkgE_ps	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (434 aa)
	DFA_02090	Putative SAM dependent methyltransferase. (300 aa)
	DFA_01847	FAD_binding_3 domain-containing protein. (318 aa)
	coq6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (500 aa)
	redB	NADPH-cytochrome-P450 oxidoreductase. (735 aa)
	idhM	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (455 aa)
	coq7	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (234 aa)
	gchA	GTP cyclohydrolase I. (286 aa)
	DFA_10506	Putative SAM dependent methyltransferase. (282 aa)
	DFA_09216	Methyltransf_11 domain-containing protein. (285 aa)
	coq2	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (459 aa)
	ptsA	6-pyruvoyl tetrahydrobiopterin synthase. (129 aa)
	pkbA	Protein serine/threonine kinase; Belongs to the protein kinase superfamily. (440 aa)
	coq5	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (327 aa)
	hspD	Heat shock protein Hsp90 family protein. (695 aa)
	DFA_01697	FAD_binding_3 domain-containing protein. (607 aa)
	DFA_01466	Non-specific serine/threonine protein kinase. (669 aa)
	idhC	Isocitrate dehydrogenase. (578 aa)
	DFA_01232	Methyltransf_11 domain-containing protein. (285 aa)
	sr	Sepiapterin reductase. (280 aa)
	coq1	Trans-prenyltransferase; Belongs to the FPP/GGPP synthase family. (485 aa)

Your Current Organism:

Cavenderia fasciculata

NCBI taxonomy Id: 1054147
Other names: C. fasciculata SH3, Cavenderia fasciculata SH3, Dictyostelium fasciculatum SH3, Dictyostelium fasciculatum strain SH3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DFA_01058	DFA_01466	F4PQL6	F4PSV2	Sepiapterin reductase.	Non-specific serine/threonine protein kinase.	0.575
DFA_01058	gchA	F4PQL6	F4PKC9	Sepiapterin reductase.	GTP cyclohydrolase I.	0.664
DFA_01058	ptsA	F4PQL6	F4Q547	Sepiapterin reductase.	6-pyruvoyl tetrahydrobiopterin synthase.	0.982
DFA_01058	sr	F4PQL6	F4PQN4	Sepiapterin reductase.	Sepiapterin reductase.	0.902
DFA_01232	DFA_09216	F4PRL1	F4Q706	Methyltransf_11 domain-containing protein.	Methyltransf_11 domain-containing protein.	0.421
DFA_01232	coq1	F4PRL1	F4PIG3	Methyltransf_11 domain-containing protein.	Trans-prenyltransferase; Belongs to the FPP/GGPP synthase family.	0.437
DFA_01232	coq3	F4PRL1	F4PUY8	Methyltransf_11 domain-containing protein.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.421
DFA_01232	coq7	F4PRL1	F4PI31	Methyltransf_11 domain-containing protein.	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.	0.487
DFA_01466	DFA_01058	F4PSV2	F4PQL6	Non-specific serine/threonine protein kinase.	Sepiapterin reductase.	0.575
DFA_01466	hspD	F4PSV2	F4Q0M6	Non-specific serine/threonine protein kinase.	Heat shock protein Hsp90 family protein.	0.804
DFA_01466	pkbA	F4PSV2	F4Q412	Non-specific serine/threonine protein kinase.	Protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.753
DFA_01466	pkgE_ps	F4PSV2	F4PN29	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.680
DFA_01466	redB	F4PSV2	F4QF17	Non-specific serine/threonine protein kinase.	NADPH-cytochrome-P450 oxidoreductase.	0.489
DFA_01466	sr	F4PSV2	F4PQN4	Non-specific serine/threonine protein kinase.	Sepiapterin reductase.	0.575
DFA_01697	DFA_01847	F4PU96	F4PV53	FAD_binding_3 domain-containing protein.	FAD_binding_3 domain-containing protein.	0.503
DFA_01697	DFA_09216	F4PU96	F4Q706	FAD_binding_3 domain-containing protein.	Methyltransf_11 domain-containing protein.	0.539
DFA_01697	coq2	F4PU96	F4Q5Q5	FAD_binding_3 domain-containing protein.	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	0.523
DFA_01697	coq3	F4PU96	F4PUY8	FAD_binding_3 domain-containing protein.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.539
DFA_01711	DFA_09216	F4PUB0	F4Q706	FAD-binding monooxygenase.	Methyltransf_11 domain-containing protein.	0.539
DFA_01711	coq2	F4PUB0	F4Q5Q5	FAD-binding monooxygenase.	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	0.523