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rpl11 rpl11 AGI47057.1 AGI47057.1 rpl10 rpl10 rpl12 rpl12 AGI47073.1 AGI47073.1 rps28e rps28e rpl24e rpl24e ndk ndk infB infB rps6e rps6e eif2g eif2g rps2 rps2 AGI47304.1 AGI47304.1 rpl44e rpl44e rpl37ae rpl37ae eif2b eif2b rps12 rps12 rps7 rps7 tuf tuf rps10 rps10 AGI47427.1 AGI47427.1 rps13 rps13 AGI47448.1 AGI47448.1 rps24e rps24e rpl40e rpl40e AGI47655.1 AGI47655.1 gltX gltX rpl31e rpl31e rps19e rps19e rpl37e rpl37e rps3ae rps3ae adk adk prf1 prf1 cmk cmk rpl15 rpl15 rpl30 rpl30 AGI48296.1 AGI48296.1 rpl18 rpl18 rpl19e rpl19e rpl32e rpl32e rpl6 rpl6 rps8 rps8 rps14 rps14 rpl5 rpl5 rps4e rps4e rpl24 rpl24 rpl14 rpl14 rps17 rps17 AGI48309.1 AGI48309.1 rpl29 rpl29 rps3 rps3 rpl22 rpl22 rps19p rps19p AGI48314.1 AGI48314.1 rpl23 rpl23 rpl4 rpl4 AGI48317.1 AGI48317.1 AGI48335.1 AGI48335.1 rps9 rps9 rpl13 rpl13 rpl18e rpl18e eif1a eif1a rpl21e rpl21e AGI48418.1 AGI48418.1 AGI48430.1 AGI48430.1 rps17e rps17e nusA nusA AGI48489.1 AGI48489.1 rpl18a rpl18a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpl11LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (150 aa)
AGI47057.1LSU ribosomal protein L1P; Belongs to the universal ribosomal protein uL1 family. (185 aa)
rpl10Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (334 aa)
rpl12LSU ribosomal protein L12AE; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (108 aa)
AGI47073.1Translation elongation factor EF-1beta. (89 aa)
rps28eSSU ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. (71 aa)
rpl24eLSU ribosomal protein L24E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL24 family. (79 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (153 aa)
infBTranslation initiation factor aIF-2/yIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (582 aa)
rps6eSSU ribosomal protein S6E; Belongs to the eukaryotic ribosomal protein eS6 family. (133 aa)
eif2gTranslation initiation factor 2 subunit gamma (aeIF-2g); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (412 aa)
rps2SSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (208 aa)
AGI47304.1Translation initiation factor 2, alpha subunit (eIF-2alpha). (260 aa)
rpl44eLSU ribosomal protein L44E; Binds to the 23S rRNA. (92 aa)
rpl37aeLSU ribosomal protein L37AE; Binds to the 23S rRNA. (92 aa)
eif2bPutative translation initiation factor aIF-2, beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (208 aa)
rps12SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (132 aa)
rps7SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (213 aa)
tufTranslation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (418 aa)
rps10SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (105 aa)
AGI47427.1Methionine aminopeptidase, type II; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). (298 aa)
rps13Archaeal ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (178 aa)
AGI47448.1LSU ribosomal protein L10AE. (151 aa)
rps24eRibosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. (103 aa)
rpl40eLSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. (49 aa)
AGI47655.1Putative ATPase, RNase L inhibitor (RLI). (596 aa)
gltXglutamyl-tRNA synthetase, archaeal and eukaryotic family; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (557 aa)
rpl31eLSU ribosomal protein L31E; Belongs to the ribosomal protein L31e family. (87 aa)
rps19eSSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (143 aa)
rpl37eLSU ribosomal protein L37E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (56 aa)
rps3aeRibosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. (238 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (207 aa)
prf1Peptide chain release factor subunit 1 (aeRF-1); Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (411 aa)
cmkPutative rRNA pseudouridine synthase, putative/cytidylate kinase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (503 aa)
rpl15Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (140 aa)
rpl30LSU ribosomal protein L30P. (157 aa)
AGI48296.1SSU ribosomal protein S5P; Belongs to the universal ribosomal protein uS5 family. (213 aa)
rpl18LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (166 aa)
rpl19eLSU ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (153 aa)
rpl32eRibosomal protein L32E; Belongs to the eukaryotic ribosomal protein eL32 family. (224 aa)
rpl6LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (185 aa)
rps8SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (129 aa)
rps14SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (48 aa)
rpl5LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (174 aa)
rps4eRibosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family. (234 aa)
rpl24Ribosomal protein L24p/L26e, archaeal/eukaryotic; Located at the polypeptide exit tunnel on the outside of the subunit. (123 aa)
rpl14LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa)
rps17SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (112 aa)
AGI48309.1Translation initiation factor 1 (eIF-1/SUI1); Belongs to the SUI1 family. (99 aa)
rpl29LSU ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (69 aa)
rps3SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (227 aa)
rpl22Ribosomal protein L22(archaeal)/L17(eukaryotic/archaeal); The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (151 aa)
rps19pSSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (155 aa)
AGI48314.1LSU ribosomal protein L2P. (208 aa)
rpl23Ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (93 aa)
rpl450S ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (258 aa)
AGI48317.1Archaeal ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (283 aa)
AGI48335.1alpha-NAC-related protein. (125 aa)
rps9SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (132 aa)
rpl13Ribosomal protein L13, archaeal/eukaryotic; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (141 aa)
rpl18eLSU ribosomal protein L18AE; Belongs to the eukaryotic ribosomal protein eL18 family. (122 aa)
eif1aTranslation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (108 aa)
rpl21eLSU ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. (97 aa)
AGI48418.1LSU ribosomal protein L15E. (208 aa)
AGI48430.1SSU ribosomal protein S15P; Belongs to the universal ribosomal protein uS15 family. (134 aa)
rps17eSSU ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family. (63 aa)
nusANusA family KH domain protein, archaeal; Participates in transcription termination. Belongs to the NusA family. (142 aa)
AGI48489.1Ribosomal protein L30E. (94 aa)
rpl18aRibosomal protein L20A (L18A). (74 aa)
Your Current Organism:
Thermoplasmatales archaeon BRNA1
NCBI taxonomy Id: 1054217
Other names: T. archaeon BRNA1
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