STRINGSTRING
AGI47529.1 AGI47529.1 AGI47524.1 AGI47524.1 AGI47515.1 AGI47515.1 AGI47514.1 AGI47514.1 rtcB rtcB queC queC serS serS AGI47421.1 AGI47421.1 AGI47360.1 AGI47360.1 AGI47358.1 AGI47358.1 AGI47329.1 AGI47329.1 AGI47317.1 AGI47317.1 AGI47263.1 AGI47263.1 AGI47188.1 AGI47188.1 purQ purQ guaAB guaAB guaAA guaAA AGI47092.1 AGI47092.1 AGI47158.1 AGI47158.1 proS proS purS purS purL purL atpE atpE atpC atpC atpF atpF atpA atpA atpB atpB atpD atpD tiaS tiaS purM purM purD purD AGI48479.1 AGI48479.1 AGI48478.1 AGI48478.1 gatE gatE AGI48456.1 AGI48456.1 AGI48368.1 AGI48368.1 AGI48364.1 AGI48364.1 AGI48334.1 AGI48334.1 aspS-2 aspS-2 gatB gatB AGI48330.1 AGI48330.1 AGI48329.1 AGI48329.1 trpS trpS AGI48286.1 AGI48286.1 argS argS AGI48277.1 AGI48277.1 cbiA cbiA nadE nadE AGI48217.1 AGI48217.1 lysS lysS hisS hisS thrS thrS AGI48188.1 AGI48188.1 AGI48187.1 AGI48187.1 AGI48185.1 AGI48185.1 AGI48184.1 AGI48184.1 AGI48183.1 AGI48183.1 AGI48141.1 AGI48141.1 AGI48140.1 AGI48140.1 lig lig AGI48131.1 AGI48131.1 AGI48119.1 AGI48119.1 AGI48106.1 AGI48106.1 AGI48105.1 AGI48105.1 AGI48081.1 AGI48081.1 AGI48080.1 AGI48080.1 AGI48070.1 AGI48070.1 AGI48068.1 AGI48068.1 AGI48049.1 AGI48049.1 AGI47996.1 AGI47996.1 AGI47986.1 AGI47986.1 AGI47979.1 AGI47979.1 AGI47976.1 AGI47976.1 AGI47959.1 AGI47959.1 pheT pheT AGI47740.1 AGI47740.1 fhs fhs AGI47716.1 AGI47716.1 cysS cysS gltX gltX purA purA aspS aspS AGI47659.1 AGI47659.1 metG metG argG argG purC purC AGI47568.1 AGI47568.1 AGI47555.1 AGI47555.1 AGI47554.1 AGI47554.1 carB carB AGI47534.1 AGI47534.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGI47529.1Nicotinic acid phosphoribosyltransferase. (397 aa)
AGI47524.1Hypothetical protein. (194 aa)
AGI47515.1isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (970 aa)
AGI47514.1Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1. (234 aa)
rtcBHypothetical protein; Belongs to the RtcB family. (483 aa)
queCpreQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (227 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (429 aa)
AGI47421.1alanyl-tRNA synthetase. (590 aa)
AGI47360.1Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase. (550 aa)
AGI47358.1Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (554 aa)
AGI47329.1tyrosyl-tRNA synthetase. (380 aa)
AGI47317.1Putative ATPases of PP-loop superfamily. (219 aa)
AGI47263.1RNA 3'-phosphate cyclase. (345 aa)
AGI47188.1ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases). (357 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (272 aa)
guaABGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (320 aa)
guaAAGMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit; Catalyzes the synthesis of GMP from XMP. (191 aa)
AGI47092.1Archaeal conserved hypothetical protein. (249 aa)
AGI47158.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase, prokaryotic. (396 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (469 aa)
purSPhosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (80 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (778 aa)
atpEArchaeal/vacuolar-type H+-ATPase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (185 aa)
atpCATP synthase A1, C subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (350 aa)
atpFArchaeal/vacuolar-type H+-ATPase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. (101 aa)
atpAArchaeal/vacuolar-type H+-ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (553 aa)
atpBArchaeal/vacuolar-type H+-ATPase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (460 aa)
atpDH(+)-transporting ATP synthase, vacuolar type, subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (212 aa)
tiaSPutative DNA-binding protein containing a Zn-ribbon domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (436 aa)
purMPhosphoribosylaminoimidazole synthetase. (338 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (441 aa)
AGI48479.1L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D. (302 aa)
AGI48478.1L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D. (118 aa)
gatEglutamyl-tRNA(Gln) amidotransferase, subunit E; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (624 aa)
AGI48456.1L-glutamine synthetase. (726 aa)
AGI48368.1Dihydropteroate synthase. (264 aa)
AGI48364.1Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. (185 aa)
AGI48334.1Alanyl-tRNA synthetase. (393 aa)
aspS-2aspartyl-tRNA synthetase, bacterial type; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (606 aa)
gatBglutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (450 aa)
AGI48330.1Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit-related amidase. (442 aa)
AGI48329.1glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, C subunit. (90 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (373 aa)
AGI48286.1phenylalanyl-tRNA synthetase, alpha subunit. (509 aa)
argSarginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (589 aa)
AGI48277.1ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases). (391 aa)
cbiACobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (447 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (259 aa)
AGI48217.1Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)/cobyrinate a,c-diamide synthase. (443 aa)
lysSlysyl-tRNA synthetase, archaeal and spirochete; Belongs to the class-I aminoacyl-tRNA synthetase family. (516 aa)
hisShistidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (416 aa)
thrSthreonyl-tRNA synthetase/Ser-tRNA(Thr) hydrolase; Belongs to the class-II aminoacyl-tRNA synthetase family. (581 aa)
AGI48188.1Mg-chelatase subunit ChlI. (610 aa)
AGI48187.1Protoporphyrin IX magnesium-chelatase. (343 aa)
AGI48185.1Cobalamin biosynthesis protein CobN-related Mg-chelatase. (1251 aa)
AGI48184.1Cobalamin biosynthesis protein CobN-related Mg-chelatase. (963 aa)
AGI48183.1Cobalamin biosynthesis protein CobN-related Mg-chelatase. (281 aa)
AGI48141.1Mg-chelatase subunit ChlI. (659 aa)
AGI48140.1Protoporphyrin IX magnesium-chelatase. (338 aa)
ligDNA ligase I, ATP-dependent (dnl1); DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (605 aa)
AGI48131.1Cobalamin biosynthesis protein CobN-related Mg-chelatase. (1229 aa)
AGI48119.1Acyl-CoA synthetase (NDP forming). (697 aa)
AGI48106.1Asparagine synthase (glutamine-hydrolyzing). (264 aa)
AGI48105.1Folylpolyglutamate synthase/dihydrofolate synthase. (413 aa)
AGI48081.1Seryl-tRNA synthetase. (273 aa)
AGI48080.1Carbamoylphosphate synthase large subunit. (381 aa)
AGI48070.1valyl-tRNA synthetase. (873 aa)
AGI48068.1glycyl-tRNA synthetase, dimeric type. (570 aa)
AGI48049.1Uncharacterized protein conserved in bacteria. (75 aa)
AGI47996.1GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit. (326 aa)
AGI47986.12'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (178 aa)
AGI47979.1Coenzyme F390 synthetase. (433 aa)
AGI47976.1phenylacetate-CoA ligase. (432 aa)
AGI47959.1leucyl-tRNA synthetase, archaeal and cytosolic family; Belongs to the class-I aminoacyl-tRNA synthetase family. (969 aa)
pheTphenylalanyl-tRNA synthetase, beta subunit. (552 aa)
AGI47740.1Asparagine synthase (glutamine-hydrolyzing). (318 aa)
fhsFormate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (560 aa)
AGI47716.1phenylacetate-CoA ligase. (349 aa)
cysScysteinyl-tRNA synthetase. (474 aa)
gltXglutamyl-tRNA synthetase, archaeal and eukaryotic family; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (557 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (434 aa)
aspSaspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). (436 aa)
AGI47659.1EMAP domain protein. (193 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (773 aa)
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (425 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (300 aa)
AGI47568.1Thiamine biosynthesis protein ThiF, family 2. (266 aa)
AGI47555.1Carbamoylphosphate synthase small subunit. (142 aa)
AGI47554.1Carbamoylphosphate synthase small subunit. (214 aa)
carBCarbamoyl-phosphate synthase large subunit; Belongs to the CarB family. (1071 aa)
AGI47534.1[NiFe] hydrogenase maturation protein HypF. (724 aa)
Your Current Organism:
Thermoplasmatales archaeon BRNA1
NCBI taxonomy Id: 1054217
Other names: T. archaeon BRNA1
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