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| | priS | Putative DNA primase, eukaryotic-type, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extensi [...] (422 aa) |
| | AGI48533.1 | Metal-dependent hydrolases of the beta-lactamase superfamily II. (256 aa) |
| | thiC | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (440 aa) |
| | purM | Phosphoribosylaminoimidazole synthetase. (338 aa) |
| | rpoH | DNA-directed RNA polymerase, subunit H, RpoH/RPB5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (89 aa) |
| | AGI48492.1 | DNA-directed RNA polymerase, subunit B'; Belongs to the RNA polymerase beta chain family. (1207 aa) |
| | AGI48491.1 | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (951 aa) |
| | rpoA2 | DNA-directed RNA polymerase, beta' subunit/160 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (494 aa) |
| | nusA | NusA family KH domain protein, archaeal; Participates in transcription termination. Belongs to the NusA family. (142 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (216 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (441 aa) |
| | thyX | Thymidylate synthase (FAD); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (223 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (181 aa) |
| | pdxS | Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (291 aa) |
| | pdxT | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (187 aa) |
| | nadK | Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (533 aa) |
| | AGI48420.1 | Thiamine biosynthesis ATP pyrophosphatase. (285 aa) |
| | trpA | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (258 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (396 aa) |
| | trpF-2 | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (199 aa) |
| | AGI48414.1 | Indole-3-glycerol phosphate synthase. (263 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (338 aa) |
| | AGI48411.1 | Anthranilate synthase, component I. (487 aa) |
| | AGI48409.1 | DNA polymerase elongation subunit (family B). (825 aa) |
| | AGI48405.1 | Archaeal conserved hypothetical protein. (92 aa) |
| | AGI48396.1 | Folate-dependent phosphoribosylglycinamide formyltransferase PurN. (272 aa) |
| | AGI48395.1 | Uroporphyrinogen-III decarboxylase. (345 aa) |
| | AGI48393.1 | Putative dinucleotide-utilizing enzyme. (268 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (316 aa) |
| | AGI48368.1 | Dihydropteroate synthase. (264 aa) |
| | rpoN | DNA-directed RNA polymerase, subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (63 aa) |
| | mptA | Conserved hypothetical protein TIGR00294; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (301 aa) |
| | cmk | Putative rRNA pseudouridine synthase, putative/cytidylate kinase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (503 aa) |
| | AGI48283.1 | Putative uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (229 aa) |
| | AGI48277.1 | ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases). (391 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (207 aa) |
| | pyrC | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (423 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (472 aa) |
| | AGI48244.1 | ACT domain-containing protein; Belongs to the UPF0237 family. (92 aa) |
| | AGI48238.1 | Hypothetical protein. (260 aa) |
| | cbiA | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (447 aa) |
| | AGI48234.1 | Siroheme synthase, N-terminal domain protein. (206 aa) |
| | nadE | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (259 aa) |
| | AGI48221.1 | Hypothetical protein. (256 aa) |
| | cbiD | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (383 aa) |
| | AGI48219.1 | Cobalamin biosynthesis protein CbiG. (348 aa) |
| | AGI48218.1 | Precorrin-6x reductase. (667 aa) |
| | AGI48217.1 | Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)/cobyrinate a,c-diamide synthase. (443 aa) |
| | AGI48210.1 | Cobalamin biosynthesis protein CbiM. (209 aa) |
| | AGI48209.1 | ABC-type cobalt transport system, periplasmic component. (108 aa) |
| | AGI48199.1 | Uroporphyrinogen-III synthase. (263 aa) |
| | AGI48197.1 | Porphobilinogen deaminase. (287 aa) |
| | hemL | Glutamate-1-semialdehyde 2,1-aminomutase. (425 aa) |
| | AGI48195.1 | Porphobilinogen synthase; Belongs to the ALAD family. (333 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (402 aa) |
| | AGI48188.1 | Mg-chelatase subunit ChlI. (610 aa) |
| | AGI48187.1 | Protoporphyrin IX magnesium-chelatase. (343 aa) |
| | AGI48179.1 | Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. (233 aa) |
| | AGI48178.1 | Precorrin-4 C11-methyltransferase/cobalt-factor II C20-methyltransferase. (251 aa) |
| | AGI48177.1 | Precorrin-3 methyltransferase. (250 aa) |
| | AGI48176.1 | precorrin-8X methylmutase. (197 aa) |
| | AGI48156.1 | 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family. (185 aa) |
| | AGI48155.1 | 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family. (94 aa) |
| | pyrI | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (158 aa) |
| | pyrB | Aspartate carbamoyltransferase. (310 aa) |
| | AGI48141.1 | Mg-chelatase subunit ChlI. (659 aa) |
| | AGI48140.1 | Protoporphyrin IX magnesium-chelatase. (338 aa) |
| | AGI48136.1 | DNA-directed RNA polymerase, subunit L. (81 aa) |
| | lig | DNA ligase I, ATP-dependent (dnl1); DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (605 aa) |
| | AGI48116.1 | Deoxycytidine triphosphate deaminase. (162 aa) |
| | cobD | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (346 aa) |
| | cobS | Cobalamin 5'-phosphate synthase/cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (312 aa) |
| | AGI48110.1 | GTP:adenosylcobinamide-phosphate guanylyltransferase. (198 aa) |
| | AGI48105.1 | Folylpolyglutamate synthase/dihydrofolate synthase. (413 aa) |
| | cobQ-2 | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (607 aa) |
| | cobQ | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (277 aa) |
| | pyrD | Dihydroorotate dehydrogenase (subfamily 1) family protein; Catalyzes the conversion of dihydroorotate to orotate. (298 aa) |
| | AGI48008.1 | 2-polyprenylphenol hydroxylase-related flavodoxin oxidoreductase. (254 aa) |
| | tbp | TATA binding protein of transcription factor TFIID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (179 aa) |
| | AGI47996.1 | GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit. (326 aa) |
| | AGI47965.1 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (749 aa) |
| | AGI47956.1 | Hypothetical protein. (140 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (203 aa) |
| | AGI47954.1 | Pyruvate:ferredoxin oxidoreductase-related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit. (198 aa) |
| | AGI47916.1 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (440 aa) |
| | AGI47894.1 | Putative methanogenesis marker protein 2. (336 aa) |
| | AGI47879.1 | Hypothetical protein. (140 aa) |
| | AGI47817.1 | TATA-box binding protein (TBP), component of TFIID and TFIIIB. (172 aa) |
| | AGI47799.1 | Hypothetical protein. (216 aa) |
| | AGI47797.1 | Molybdenum cofactor biosynthesis enzyme. (276 aa) |
| | AGI47789.1 | Hypothetical protein. (284 aa) |
| | AGI47781.1 | Pyridoxal/pyridoxine/pyridoxamine kinase. (282 aa) |
| | AGI47738.1 | Uroporphyrinogen-III decarboxylase. (336 aa) |
| | dbh | Nucleotidyltransferase/DNA polymerase involved in DNA repair; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. (427 aa) |
| | AGI47699.1 | Cytidyltransferase-related domain protein. (140 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (434 aa) |
| | mptD | Archaeal conserved hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD). (127 aa) |
| | nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (300 aa) |
| | dnaG | DNA primase (bacterial type); RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (570 aa) |
| | aroA-3 | Putative phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (265 aa) |
| | AGI47623.1 | Phosphomethylpyrimidine kinase. (432 aa) |
| | thiM | Hydroxyethylthiazole kinase, sugar kinase family; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (260 aa) |
| | thiE | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (213 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (300 aa) |
| | AGI47604.1 | Competence/damage-inducible protein CinA C-terminal domain protein. (160 aa) |
| | AGI47603.1 | Nicotinamide-nucleotide adenylyltransferase. (177 aa) |
| | AGI47571.1 | Prephenate dehydratase. (189 aa) |
| | AGI47567.1 | Thiazole-phosphate synthase. (256 aa) |
| | AGI47565.1 | Thiamine monophosphate synthase. (197 aa) |
| | aroA-2 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (421 aa) |
| | aroK | Shikimate kinase. (270 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (433 aa) |
| | aroB | Putative alternative 3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. (340 aa) |
| | aroA | Putative phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (263 aa) |
| | AGI47555.1 | Carbamoylphosphate synthase small subunit. (142 aa) |
| | AGI47554.1 | Carbamoylphosphate synthase small subunit. (214 aa) |
| | carB | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. (1071 aa) |
| | mtnP | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (264 aa) |
| | AGI47532.1 | NaMN:DMB phosphoribosyltransferase. (228 aa) |
| | AGI47531.1 | Hypothetical protein. (137 aa) |
| | AGI47529.1 | Nicotinic acid phosphoribosyltransferase. (397 aa) |
| | AGI47506.1 | Archaeal conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (168 aa) |
| | AGI47504.1 | DNA-directed RNA polymerase (rpoE), archaeal and eukaryotic form. (190 aa) |
| | AGI47501.1 | Uroporphyrinogen-III decarboxylase. (348 aa) |
| | AGI47465.1 | Methyltransferase, MtaA/CmuA family. (337 aa) |
| | queE | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (209 aa) |
| | queC | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (227 aa) |
| | AGI47451.1 | 6-pyruvoyl-tetrahydropterin synthase. (158 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (429 aa) |
| | polC | DNA polymerase, archaeal type II, large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1128 aa) |
| | AGI47432.1 | DNA-directed RNA polymerase, alpha subunit/40 kD subunit. (287 aa) |
| | AGI47418.1 | cob(I)alamin adenosyltransferase. (180 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (353 aa) |
| | AGI47360.1 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase. (550 aa) |
| | AGI47333.1 | Hypothetical protein. (44 aa) |
| | AGI47328.1 | Adenine/guanine phosphoribosyltransferase-related PRPP-binding protein. (190 aa) |
| | AGI47320.1 | HRDC domain protein. (1244 aa) |
| | AGI47276.1 | NCAIR mutase (PurE)-related protein. (250 aa) |
| | AGI47266.1 | Pyruvate-formate lyase-activating enzyme. (228 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (178 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase/5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa) |
| | AGI47205.1 | DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS. (92 aa) |
| | AGI47202.1 | Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (272 aa) |
| | AGI47199.1 | IMP cyclohydrolase. (542 aa) |
| | AGI47195.1 | Thiamine biosynthesis ATP pyrophosphatase. (208 aa) |
| | AGI47188.1 | ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases). (357 aa) |
| | rpoK | DNA-directed RNA polymerase, subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (61 aa) |
| | AGI47167.1 | Transcriptional regulator of a riboflavin/FAD biosynthetic operon. (229 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (272 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (778 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (80 aa) |
| | AGI47161.1 | Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (281 aa) |
| | AGI47159.1 | Putative archaeal kinase (sugar kinase superfamily). (288 aa) |
| | AGI47158.1 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase, prokaryotic. (396 aa) |
| | tmk | Thymidylate kinase. (198 aa) |
| | AGI47140.1 | Prephenate dehydrogenase. (365 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (153 aa) |
| | AGI47125.1 | Hypothetical protein. (459 aa) |
| | AGI47110.1 | Nucleotide sugar dehydrogenase. (422 aa) |
| | AGI47098.1 | Phosphoenolpyruvate phosphomutase. (431 aa) |
| | AGI47092.1 | Archaeal conserved hypothetical protein. (249 aa) |
| | AGI47076.1 | Mannose-1-phosphate guanylyltransferase; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). (343 aa) |
| | AGI47069.1 | Eukaryotic-type DNA primase, large subunit. (244 aa) |
| | AGI47067.1 | Eukaryotic-type DNA primase, large subunit. (83 aa) |
| | AGI47065.1 | Putative nucleotide kinase (CMP and AMP kinases -like protein); Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (177 aa) |
| | guaAA | GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit; Catalyzes the synthesis of GMP from XMP. (191 aa) |
| | guaAB | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (320 aa) |
| | purE | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (161 aa) |
| | tfb | Transcription initiation factor IIB (TFIIB); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (311 aa) |
| | AGI47041.1 | Pyridoxal-phosphate dependent TrpB-like enzyme. (442 aa) |
| | polB | Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (480 aa) |
| | atpD | H(+)-transporting ATP synthase, vacuolar type, subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (212 aa) |
| | atpB | Archaeal/vacuolar-type H+-ATPase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (460 aa) |
| | atpA | Archaeal/vacuolar-type H+-ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (553 aa) |
| | atpF | Archaeal/vacuolar-type H+-ATPase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. (101 aa) |
| | atpC | ATP synthase A1, C subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (350 aa) |
| | atpE | Archaeal/vacuolar-type H+-ATPase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (185 aa) |
