STRINGSTRING
rpl18a rpl18a priS priS gyrA gyrA AGI48489.1 AGI48489.1 rps17e rps17e AGI48430.1 AGI48430.1 AGI48423.1 AGI48423.1 AGI48418.1 AGI48418.1 AGI48409.1 AGI48409.1 rpl21e rpl21e AGI48402.1 AGI48402.1 rpl18e rpl18e rpl13 rpl13 rps9 rps9 AGI48317.1 AGI48317.1 rpl4 rpl4 rpl23 rpl23 AGI48314.1 AGI48314.1 rps19p rps19p rpl22 rpl22 rps3 rps3 rpl29 rpl29 rps17 rps17 rpl14 rpl14 rpl24 rpl24 rps4e rps4e rpl5 rpl5 rps14 rps14 rps8 rps8 rpl6 rpl6 rpl32e rpl32e rpl19e rpl19e rpl18 rpl18 AGI48296.1 AGI48296.1 rpl30 rpl30 rpl15 rpl15 rps3ae rps3ae rpl37e rpl37e AGI48247.1 AGI48247.1 top6A top6A top6B top6B AGI48028.1 AGI48028.1 rps19e rps19e rpl39e rpl39e rpl31e rpl31e AGI47882.1 AGI47882.1 rfcS rfcS AGI47713.1 AGI47713.1 AGI47676.1 AGI47676.1 dnaG dnaG rpl40e rpl40e rps27ae rps27ae rps24e rps24e AGI47448.1 AGI47448.1 AGI47434.1 AGI47434.1 rps11 rps11 rps4 rps4 rps13 rps13 rps2 rps2 AGI47214.1 AGI47214.1 smc smc rps27e rps27e rpl44e rpl44e rpl37ae rpl37ae AGI47338.1 AGI47338.1 rps8e rps8e rps12 rps12 rps7 rps7 rps10 rps10 AGI47016.1 AGI47016.1 spt5 spt5 rpl11 rpl11 AGI47057.1 AGI47057.1 rpl10 rpl10 rpl12 rpl12 AGI47067.1 AGI47067.1 AGI47069.1 AGI47069.1 rpl7ae rpl7ae rps28e rps28e rpl24e rpl24e rps6e rps6e AGI47135.1 AGI47135.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpl18aRibosomal protein L20A (L18A). (74 aa)
priSPutative DNA primase, eukaryotic-type, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extensi [...] (422 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (820 aa)
AGI48489.1Ribosomal protein L30E. (94 aa)
rps17eSSU ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family. (63 aa)
AGI48430.1SSU ribosomal protein S15P; Belongs to the universal ribosomal protein uS15 family. (134 aa)
AGI48423.1Recombination protein MgsA. (451 aa)
AGI48418.1LSU ribosomal protein L15E. (208 aa)
AGI48409.1DNA polymerase elongation subunit (family B). (825 aa)
rpl21eLSU ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. (97 aa)
AGI48402.1Universal archaeal KH domain protein; arCOG04150. (182 aa)
rpl18eLSU ribosomal protein L18AE; Belongs to the eukaryotic ribosomal protein eL18 family. (122 aa)
rpl13Ribosomal protein L13, archaeal/eukaryotic; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (141 aa)
rps9SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (132 aa)
AGI48317.1Archaeal ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (283 aa)
rpl450S ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (258 aa)
rpl23Ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (93 aa)
AGI48314.1LSU ribosomal protein L2P. (208 aa)
rps19pSSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (155 aa)
rpl22Ribosomal protein L22(archaeal)/L17(eukaryotic/archaeal); The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (151 aa)
rps3SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (227 aa)
rpl29LSU ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (69 aa)
rps17SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (112 aa)
rpl14LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa)
rpl24Ribosomal protein L24p/L26e, archaeal/eukaryotic; Located at the polypeptide exit tunnel on the outside of the subunit. (123 aa)
rps4eRibosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family. (234 aa)
rpl5LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (174 aa)
rps14SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (48 aa)
rps8SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (129 aa)
rpl6LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (185 aa)
rpl32eRibosomal protein L32E; Belongs to the eukaryotic ribosomal protein eL32 family. (224 aa)
rpl19eLSU ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (153 aa)
rpl18LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (166 aa)
AGI48296.1SSU ribosomal protein S5P; Belongs to the universal ribosomal protein uS5 family. (213 aa)
rpl30LSU ribosomal protein L30P. (157 aa)
rpl15Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (140 aa)
rps3aeRibosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. (238 aa)
rpl37eLSU ribosomal protein L37E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (56 aa)
AGI48247.1Molecular chaperone, HSP90 family. (619 aa)
top6ADNA topoisomerase VI, subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (362 aa)
top6BDNA topoisomerase VI, B subunit; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (684 aa)
AGI48028.1Hypothetical protein. (367 aa)
rps19eSSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (143 aa)
rpl39eLSU ribosomal protein L39E; Belongs to the eukaryotic ribosomal protein eL39 family. (53 aa)
rpl31eLSU ribosomal protein L31E; Belongs to the ribosomal protein L31e family. (87 aa)
AGI47882.1DNA polymerase III, delta subunit. (484 aa)
rfcSReplication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (318 aa)
AGI47713.1Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. (395 aa)
AGI47676.1DNA repair exonuclease. (399 aa)
dnaGDNA primase (bacterial type); RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (570 aa)
rpl40eLSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. (49 aa)
rps27aeSSU ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family. (57 aa)
rps24eRibosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. (103 aa)
AGI47448.1LSU ribosomal protein L10AE. (151 aa)
AGI47434.1Small GTP-binding protein domain protein. (335 aa)
rps11SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (124 aa)
rps4SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (220 aa)
rps13Archaeal ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (178 aa)
rps2SSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (208 aa)
AGI47214.1Ribulose 1,5-bisphosphate carboxylase, large subunit. (412 aa)
smcChromosome segregation protein SMC, primarily archaeal type; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1202 aa)
rps27eSSU ribosomal protein S27E. (55 aa)
rpl44eLSU ribosomal protein L44E; Binds to the 23S rRNA. (92 aa)
rpl37aeLSU ribosomal protein L37AE; Binds to the 23S rRNA. (92 aa)
AGI47338.1Conserved hypothetical protein TIGR00291. (232 aa)
rps8eSSU ribosomal protein S8E. (128 aa)
rps12SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (132 aa)
rps7SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (213 aa)
rps10SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (105 aa)
AGI47016.1Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. (411 aa)
spt5Ribosomal protein L24p/L26e, archaeal; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (274 aa)
rpl11LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (150 aa)
AGI47057.1LSU ribosomal protein L1P; Belongs to the universal ribosomal protein uL1 family. (185 aa)
rpl10Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (334 aa)
rpl12LSU ribosomal protein L12AE; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (108 aa)
AGI47067.1Eukaryotic-type DNA primase, large subunit. (83 aa)
AGI47069.1Eukaryotic-type DNA primase, large subunit. (244 aa)
rpl7aeLSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (121 aa)
rps28eSSU ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. (71 aa)
rpl24eLSU ribosomal protein L24E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL24 family. (79 aa)
rps6eSSU ribosomal protein S6E; Belongs to the eukaryotic ribosomal protein eS6 family. (133 aa)
AGI47135.1Putative PilT protein; Vapc superfamily. (104 aa)
Your Current Organism:
Thermoplasmatales archaeon BRNA1
NCBI taxonomy Id: 1054217
Other names: T. archaeon BRNA1
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