(19 nodes) Chromosome organization network (Thermoplasmatales archaeon BRNA1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AGI47193.1	Rad3-related DNA helicase. (625 aa)
	smc	Chromosome segregation protein SMC, primarily archaeal type; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1202 aa)
	AGI47264.1	Putative ATPase. (484 aa)
	hel308	Superfamily II helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (760 aa)
	AGI47633.1	Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. (504 aa)
	AGI47783.1	Rad3-related DNA helicase. (655 aa)
	AGI48028.1	Hypothetical protein. (367 aa)
	AGI48031.1	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains). (1057 aa)
	AGI48073.1	Superfamily II DNA and RNA helicase. (482 aa)
	AGI48077.1	Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. (588 aa)
	AGI48134.1	ERCC4-like helicase. (516 aa)
	top6B	DNA topoisomerase VI, B subunit; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (684 aa)
	top6A	DNA topoisomerase VI, subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (362 aa)
	AGI48247.1	Molecular chaperone, HSP90 family. (619 aa)
	AGI48266.1	Hypothetical protein. (144 aa)
	AGI48349.1	Lhr-like helicase. (745 aa)
	AGI48506.1	Lhr-like helicase. (915 aa)
	gyrA	DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (820 aa)
	AGI48523.1	Putative ATPase involved in replication control, Cdc46/Mcm family; Belongs to the MCM family. (714 aa)

Your Current Organism:

Thermoplasmatales archaeon BRNA1

NCBI taxonomy Id: 1054217
Other names: T. archaeon BRNA1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGI47193.1	AGI47783.1	TALC_00179	TALC_00787	Rad3-related DNA helicase.	Rad3-related DNA helicase.	0.909
AGI47633.1	AGI48073.1	TALC_00634	TALC_01082	Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family.	Superfamily II DNA and RNA helicase.	0.905
AGI47633.1	AGI48077.1	TALC_00634	TALC_01087	Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family.	Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family.	0.906
AGI47633.1	hel308	TALC_00634	TALC_00601	Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family.	Superfamily II helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.	0.638
AGI47783.1	AGI47193.1	TALC_00787	TALC_00179	Rad3-related DNA helicase.	Rad3-related DNA helicase.	0.909
AGI48028.1	AGI48031.1	TALC_01036	TALC_01039	Hypothetical protein.	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains).	0.563
AGI48028.1	AGI48134.1	TALC_01036	TALC_01145	Hypothetical protein.	ERCC4-like helicase.	0.426
AGI48031.1	AGI48028.1	TALC_01039	TALC_01036	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains).	Hypothetical protein.	0.563
AGI48031.1	AGI48134.1	TALC_01039	TALC_01145	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains).	ERCC4-like helicase.	0.553
AGI48073.1	AGI47633.1	TALC_01082	TALC_00634	Superfamily II DNA and RNA helicase.	Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family.	0.905
AGI48073.1	AGI48077.1	TALC_01082	TALC_01087	Superfamily II DNA and RNA helicase.	Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family.	0.905
AGI48073.1	hel308	TALC_01082	TALC_00601	Superfamily II DNA and RNA helicase.	Superfamily II helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.	0.640
AGI48077.1	AGI47633.1	TALC_01087	TALC_00634	Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family.	Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family.	0.906
AGI48077.1	AGI48073.1	TALC_01087	TALC_01082	Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family.	Superfamily II DNA and RNA helicase.	0.905
AGI48077.1	hel308	TALC_01087	TALC_00601	Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family.	Superfamily II helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.	0.639
AGI48134.1	AGI48028.1	TALC_01145	TALC_01036	ERCC4-like helicase.	Hypothetical protein.	0.426
AGI48134.1	AGI48031.1	TALC_01145	TALC_01039	ERCC4-like helicase.	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains).	0.553
AGI48134.1	smc	TALC_01145	TALC_00233	ERCC4-like helicase.	Chromosome segregation protein SMC, primarily archaeal type; Required for chromosome condensation and partitioning. Belongs to the SMC family.	0.495
AGI48247.1	top6A	TALC_01262	TALC_01216	Molecular chaperone, HSP90 family.	DNA topoisomerase VI, subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family.	0.793
AGI48506.1	top6B	TALC_01538	TALC_01215	Lhr-like helicase.	DNA topoisomerase VI, B subunit; Relaxes both positive and negative superturns and exhibits a strong decatenase activity.	0.467