STRINGSTRING
rpoK rpoK AGI47186.1 AGI47186.1 AGI47195.1 AGI47195.1 csl4 csl4 AGI47203.1 AGI47203.1 AGI47205.1 AGI47205.1 pcn pcn AGI47211.1 AGI47211.1 kptA kptA AGI47219.1 AGI47219.1 AGI47238.1 AGI47238.1 AGI47241.1 AGI47241.1 smc smc AGI47263.1 AGI47263.1 AGI47284.1 AGI47284.1 radA radA cca cca AGI47320.1 AGI47320.1 AGI47329.1 AGI47329.1 AGI47330.1 AGI47330.1 AGI47332.1 AGI47332.1 AGI47333.1 AGI47333.1 rrp42 rrp42 AGI47336.1 AGI47336.1 rrp4 rrp4 AGI47340.1 AGI47340.1 AGI47345.1 AGI47345.1 AGI47361.1 AGI47361.1 AGI47362.1 AGI47362.1 AGI47377.1 AGI47377.1 AGI47390.1 AGI47390.1 AGI47401.1 AGI47401.1 AGI47421.1 AGI47421.1 AGI47426.1 AGI47426.1 AGI47432.1 AGI47432.1 polC polC AGI47444.1 AGI47444.1 serS serS AGI47446.1 AGI47446.1 rnp4 rnp4 rtcB rtcB AGI47466.1 AGI47466.1 AGI47467.1 AGI47467.1 AGI47488.1 AGI47488.1 AGI47494.1 AGI47494.1 AGI47504.1 AGI47504.1 AGI47513.1 AGI47513.1 AGI47515.1 AGI47515.1 AGI47517.1 AGI47517.1 fen fen rnz rnz AGI47525.1 AGI47525.1 AGI47542.1 AGI47542.1 pelA pelA AGI47582.1 AGI47582.1 AGI47596.1 AGI47596.1 hel308 hel308 tgtA tgtA AGI47653.1 AGI47653.1 AGI47654.1 AGI47654.1 metG metG AGI47659.1 AGI47659.1 AGI47660.1 AGI47660.1 dnaG dnaG AGI47675.1 AGI47675.1 AGI47676.1 AGI47676.1 aspS aspS AGI47680.1 AGI47680.1 AGI47684.1 AGI47684.1 gltX gltX taw1 taw1 AGI47882.1 AGI47882.1 pheT pheT trmY trmY AGI47956.1 AGI47956.1 AGI47959.1 AGI47959.1 AGI47963.1 AGI47963.1 AGI47965.1 AGI47965.1 AGI47984.1 AGI47984.1 tbp tbp AGI48022.1 AGI48022.1 AGI48023.1 AGI48023.1 AGI48026.1 AGI48026.1 AGI48028.1 AGI48028.1 AGI48038.1 AGI48038.1 AGI48068.1 AGI48068.1 AGI48070.1 AGI48070.1 AGI48074.1 AGI48074.1 AGI48081.1 AGI48081.1 AGI48099.1 AGI48099.1 AGI48104.1 AGI48104.1 topA topA AGI48117.1 AGI48117.1 AGI48134.1 AGI48134.1 lig lig AGI48136.1 AGI48136.1 truD truD AGI48144.1 AGI48144.1 AGI48172.1 AGI48172.1 thrS thrS hisS hisS top6B top6B top6A top6A lysS lysS AGI48226.1 AGI48226.1 AGI48233.1 AGI48233.1 AGI48244.1 AGI48244.1 AGI48247.1 AGI48247.1 AGI48266.1 AGI48266.1 argS argS dtdA dtdA AGI48286.1 AGI48286.1 trpS trpS rnp1 rnp1 AGI48320.1 AGI48320.1 rnhB rnhB aspS-2 aspS-2 AGI48334.1 AGI48334.1 AGI48342.1 AGI48342.1 AGI48343.1 AGI48343.1 AGI48349.1 AGI48349.1 AGI48350.1 AGI48350.1 AGI48356.1 AGI48356.1 rpoN rpoN AGI48361.1 AGI48361.1 AGI48386.1 AGI48386.1 AGI48394.1 AGI48394.1 AGI48402.1 AGI48402.1 AGI48403.1 AGI48403.1 AGI48405.1 AGI48405.1 rsmA rsmA AGI48409.1 AGI48409.1 AGI48420.1 AGI48420.1 AGI48423.1 AGI48423.1 flpA flpA AGI48431.1 AGI48431.1 kae1 kae1 dnaJ dnaJ truA truA AGI48483.1 AGI48483.1 nusA nusA rpoA2 rpoA2 AGI48491.1 AGI48491.1 AGI48492.1 AGI48492.1 rpoH rpoH AGI48495.1 AGI48495.1 AGI48500.1 AGI48500.1 AGI48501.1 AGI48501.1 AGI48506.1 AGI48506.1 rlmE rlmE gyrA gyrA AGI48513.1 AGI48513.1 AGI48514.1 AGI48514.1 AGI48515.1 AGI48515.1 AGI48517.1 AGI48517.1 AGI48525.1 AGI48525.1 AGI48534.1 AGI48534.1 priS priS tiaS tiaS AGI47032.1 AGI47032.1 polB polB AGI47019.1 AGI47019.1 AGI47016.1 AGI47016.1 AGI47067.1 AGI47067.1 AGI47062.1 AGI47062.1 dbh dbh cysS cysS AGI47712.1 AGI47712.1 AGI47713.1 AGI47713.1 AGI47163.1 AGI47163.1 rfcS rfcS AGI47724.1 AGI47724.1 AGI47733.1 AGI47733.1 AGI47756.1 AGI47756.1 AGI47762.1 AGI47762.1 AGI47763.1 AGI47763.1 AGI47807.1 AGI47807.1 AGI47812.1 AGI47812.1 AGI47814.1 AGI47814.1 tfb tfb AGI47815.1 AGI47815.1 AGI47816.1 AGI47816.1 AGI47817.1 AGI47817.1 AGI47818.1 AGI47818.1 AGI47874.1 AGI47874.1 AGI47044.1 AGI47044.1 proS proS AGI47153.1 AGI47153.1 AGI47151.1 AGI47151.1 AGI47148.1 AGI47148.1 AGI47135.1 AGI47135.1 rpl7ae rpl7ae AGI47125.1 AGI47125.1 AGI47102.1 AGI47102.1 AGI47069.1 AGI47069.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
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rpoKDNA-directed RNA polymerase, subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (61 aa)
AGI47186.1Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit-related ssDNA-binding protein. (453 aa)
AGI47195.1Thiamine biosynthesis ATP pyrophosphatase. (208 aa)
csl4Putative RNA-binding protein (consists of S1 domain and a Zn-ribbon domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (181 aa)
AGI47203.1Putative exonuclease of the beta-lactamase fold involved in RNA processing. (410 aa)
AGI47205.1DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS. (92 aa)
pcnDNA polymerase sliding clamp subunit (PCNA-like protein); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. (245 aa)
AGI47211.1Putative methyltransferase. (336 aa)
kptARNA:NAD 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (216 aa)
AGI47219.1Protein of unknown function (DUF1743). (316 aa)
AGI47238.1Putative nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module. (141 aa)
AGI47241.1uracil-DNA glycosylase, family 4. (180 aa)
smcChromosome segregation protein SMC, primarily archaeal type; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1202 aa)
AGI47263.1RNA 3'-phosphate cyclase. (345 aa)
AGI47284.1Putative DNA modification methylase. (330 aa)
radADNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (314 aa)
ccaCCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (442 aa)
AGI47320.1HRDC domain protein. (1244 aa)
AGI47329.1tyrosyl-tRNA synthetase. (380 aa)
AGI47330.1Exopolyphosphatase-related protein. (330 aa)
AGI47332.1Archaeal conserved hypothetical protein (DUF2144). (79 aa)
AGI47333.1Hypothetical protein. (44 aa)
rrp42RNase PH-related exoribonuclease; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. (260 aa)
AGI47336.1Ribosomal RNA-processing protein RRP41/SKI6. (247 aa)
rrp4RNA-binding protein Rrp4 and related proteins (containing S1 domain and KH domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (240 aa)
AGI47340.1Hypothetical protein. (122 aa)
AGI47345.1Putative ICC-like phosphoesterase. (268 aa)
AGI47361.1Topoisomerase DNA binding C4 zinc finger. (85 aa)
AGI47362.1Site-specific recombinase XerD. (344 aa)
AGI47377.1Site-specific DNA methylase. (280 aa)
AGI47390.1MiaB-like tRNA modifying enzyme, archaeal-type. (410 aa)
AGI47401.1DNA polymerase III, epsilon subunit-related 3'-5' exonuclease. (269 aa)
AGI47421.1alanyl-tRNA synthetase. (590 aa)
AGI47426.1Sua5/YciO/YrdC/YwlC family protein. (212 aa)
AGI47432.1DNA-directed RNA polymerase, alpha subunit/40 kD subunit. (287 aa)
polCDNA polymerase, archaeal type II, large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1128 aa)
AGI47444.1tRNA-dihydrouridine synthase. (338 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (429 aa)
AGI47446.1Putative RNA-binding protein containing KH domain, possibly ribosomal protein. (98 aa)
rnp4RNase P subunit RPR2; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (105 aa)
rtcBHypothetical protein; Belongs to the RtcB family. (483 aa)
AGI47466.1Putative phosphoesterase, SbcD/Mre11-related protein. (242 aa)
AGI47467.1Single-stranded DNA-specific exonuclease. (467 aa)
AGI47488.1Hypothetical protein. (138 aa)
AGI47494.1Putative phosphatase. (230 aa)
AGI47504.1DNA-directed RNA polymerase (rpoE), archaeal and eukaryotic form. (190 aa)
AGI47513.1Mg-dependent DNase. (234 aa)
AGI47515.1isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (970 aa)
AGI47517.1Hypothetical protein. (324 aa)
fenFlap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] (342 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (302 aa)
AGI47525.1Hypothetical protein. (318 aa)
AGI47542.1Histidinol phosphatase and related hydrolases of the PHP family. (215 aa)
pelAPutative translation factor pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (343 aa)
AGI47582.1Putative phosphatase. (221 aa)
AGI47596.1Hypothetical protein. (155 aa)
hel308Superfamily II helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (760 aa)
tgtAtRNA-guanine transglycosylase, archaeosine-15-forming; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (646 aa)
AGI47653.1Hypothetical protein. (159 aa)
AGI47654.1Putative metal-dependent phosphoesterases (PHP family). (155 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (773 aa)
AGI47659.1EMAP domain protein. (193 aa)
AGI47660.1Putative metal-dependent phosphoesterases (PHP family). (218 aa)
dnaGDNA primase (bacterial type); RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (570 aa)
AGI47675.1Hypothetical protein. (708 aa)
AGI47676.1DNA repair exonuclease. (399 aa)
aspSaspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). (436 aa)
AGI47680.1Archaeal holliday junction resolvase (hjc). (194 aa)
AGI47684.1N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (372 aa)
gltXglutamyl-tRNA synthetase, archaeal and eukaryotic family; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (557 aa)
taw1Fe-S oxidoreductase; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (327 aa)
AGI47882.1DNA polymerase III, delta subunit. (484 aa)
pheTphenylalanyl-tRNA synthetase, beta subunit. (552 aa)
trmYHypothetical protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. (198 aa)
AGI47956.1Hypothetical protein. (140 aa)
AGI47959.1leucyl-tRNA synthetase, archaeal and cytosolic family; Belongs to the class-I aminoacyl-tRNA synthetase family. (969 aa)
AGI47963.1Universal archaeal KH-domain/beta-lactamase-domain protein; arCOG01782. (634 aa)
AGI47965.1Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (749 aa)
AGI47984.1TPR repeat protein, SEL1 subfamily. (594 aa)
tbpTATA binding protein of transcription factor TFIID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (179 aa)
AGI48022.1Exodeoxyribonuclease VII, small subunit. (83 aa)
AGI48023.1Exodeoxyribonuclease VII, large subunit. (443 aa)
AGI48026.1Hypothetical protein. (185 aa)
AGI48028.1Hypothetical protein. (367 aa)
AGI48038.1Hypothetical protein. (252 aa)
AGI48068.1glycyl-tRNA synthetase, dimeric type. (570 aa)
AGI48070.1valyl-tRNA synthetase. (873 aa)
AGI48074.1ybaK/ebsC protein. (160 aa)
AGI48081.1Seryl-tRNA synthetase. (273 aa)
AGI48099.1O-6-methylguanine DNA methyltransferase. (155 aa)
AGI48104.1DNA-(apurinic or apyrimidinic site) lyase/endonuclease III. (206 aa)
topATopoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superco [...] (813 aa)
AGI48117.1Putative methyltransferase. (333 aa)
AGI48134.1ERCC4-like helicase. (516 aa)
ligDNA ligase I, ATP-dependent (dnl1); DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (605 aa)
AGI48136.1DNA-directed RNA polymerase, subunit L. (81 aa)
truDConserved hypothetical protein TIGR00094; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (437 aa)
AGI48144.1Queuine tRNA-ribosyltransferase containing PUA domain. (566 aa)
AGI48172.1Ribonuclease HI. (134 aa)
thrSthreonyl-tRNA synthetase/Ser-tRNA(Thr) hydrolase; Belongs to the class-II aminoacyl-tRNA synthetase family. (581 aa)
hisShistidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (416 aa)
top6BDNA topoisomerase VI, B subunit; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (684 aa)
top6ADNA topoisomerase VI, subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (362 aa)
lysSlysyl-tRNA synthetase, archaeal and spirochete; Belongs to the class-I aminoacyl-tRNA synthetase family. (516 aa)
AGI48226.1Excinuclease ATPase subunit. (759 aa)
AGI48233.1Putative HD superfamily hydrolase. (214 aa)
AGI48244.1ACT domain-containing protein; Belongs to the UPF0237 family. (92 aa)
AGI48247.1Molecular chaperone, HSP90 family. (619 aa)
AGI48266.1Hypothetical protein. (144 aa)
argSarginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (589 aa)
dtdAArchaeal conserved hypothetical protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. (281 aa)
AGI48286.1phenylalanyl-tRNA synthetase, alpha subunit. (509 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (373 aa)
rnp1RNase P/RNase MRP subunit p29; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (84 aa)
AGI48320.1Conserved hypothetical protein TIGR01210. (332 aa)
rnhBRibonuclease H, mammalian HI/archaeal HII subfamily; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (214 aa)
aspS-2aspartyl-tRNA synthetase, bacterial type; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (606 aa)
AGI48334.1Alanyl-tRNA synthetase. (393 aa)
AGI48342.1RecA/RadA recombinase. (206 aa)
AGI48343.1Mn2+-dependent serine/threonine protein kinase. (211 aa)
AGI48349.1Lhr-like helicase. (745 aa)
AGI48350.1Hypothetical protein. (434 aa)
AGI48356.1Superfamily I DNA and RNA helicase. (815 aa)
rpoNDNA-directed RNA polymerase, subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (63 aa)
AGI48361.1Endonuclease IV. (377 aa)
AGI48386.1Hypothetical protein. (345 aa)
AGI48394.1Hypothetical protein. (135 aa)
AGI48402.1Universal archaeal KH domain protein; arCOG04150. (182 aa)
AGI48403.1Conserved hypothetical protein TIGR01213. (412 aa)
AGI48405.1Archaeal conserved hypothetical protein. (92 aa)
rsmADimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (263 aa)
AGI48409.1DNA polymerase elongation subunit (family B). (825 aa)
AGI48420.1Thiamine biosynthesis ATP pyrophosphatase. (285 aa)
AGI48423.1Recombination protein MgsA. (451 aa)
flpArRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (219 aa)
AGI48431.1Single-stranded DNA-specific exonuclease. (451 aa)
kae1O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. (327 aa)
dnaJChaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (379 aa)
truAPseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (262 aa)
AGI48483.1Putative RNA-binding protein of the translin family. (194 aa)
nusANusA family KH domain protein, archaeal; Participates in transcription termination. Belongs to the NusA family. (142 aa)
rpoA2DNA-directed RNA polymerase, beta' subunit/160 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (494 aa)
AGI48491.1DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (951 aa)
AGI48492.1DNA-directed RNA polymerase, subunit B'; Belongs to the RNA polymerase beta chain family. (1207 aa)
rpoHDNA-directed RNA polymerase, subunit H, RpoH/RPB5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (89 aa)
AGI48495.1Histone acetyltransferase, ELP3 family. (510 aa)
AGI48500.1Putative domain HDIG. (177 aa)
AGI48501.1Archaeal conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (167 aa)
AGI48506.1Lhr-like helicase. (915 aa)
rlmE23S rRNA Um-2552 2'-O-methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (222 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (820 aa)
AGI48513.1Endonuclease IV. (272 aa)
AGI48514.18-oxoguanine DNA glycosylase, N-terminal domain protein. (163 aa)
AGI48515.1Hypothetical protein. (88 aa)
AGI48517.1Lhr-like helicase. (1787 aa)
AGI48525.1Hypothetical protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. (170 aa)
AGI48534.1Putative metal-dependent hydrolase (urease superfamily). (277 aa)
priSPutative DNA primase, eukaryotic-type, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extensi [...] (422 aa)
tiaSPutative DNA-binding protein containing a Zn-ribbon domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (436 aa)
AGI47032.1Sugar phosphate isomerase/epimerase. (254 aa)
polBArchaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (480 aa)
AGI47019.1ATP synthase H subunit. (116 aa)
AGI47016.1Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. (411 aa)
AGI47067.1Eukaryotic-type DNA primase, large subunit. (83 aa)
AGI47062.1RNA methyltransferase, TrmH family, group 1. (238 aa)
dbhNucleotidyltransferase/DNA polymerase involved in DNA repair; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. (427 aa)
cysScysteinyl-tRNA synthetase. (474 aa)
AGI47712.1Conserved hypothetical protein TIGR00269. (308 aa)
AGI47713.1Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. (395 aa)
AGI47163.1tRNA(1-methyladenosine) methyltransferase-related methyltransferase. (255 aa)
rfcSReplication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (318 aa)
AGI47724.1Putative phosphatase. (181 aa)
AGI47733.1Ribosomal large subunit pseudouridine synthase F. (244 aa)
AGI47756.1DNA repair photolyase. (264 aa)
AGI47762.1Site-specific recombinase, DNA invertase. (258 aa)
AGI47763.1Site-specific recombinase, DNA invertase. (292 aa)
AGI47807.1Site-specific recombinase, DNA invertase. (327 aa)
AGI47812.1Exonuclease. (210 aa)
AGI47814.1Type I restriction system adenine methylase (hsdM). (851 aa)
tfbTranscription initiation factor IIB (TFIIB); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (311 aa)
AGI47815.1Restriction endonuclease S subunit. (381 aa)
AGI47816.1Type I site-specific deoxyribonuclease, HsdR family. (1007 aa)
AGI47817.1TATA-box binding protein (TBP), component of TFIID and TFIIIB. (172 aa)
AGI47818.1Hypothetical protein. (617 aa)
AGI47874.1Site-specific recombinase XerD. (494 aa)
AGI47044.1tRNA intron endonuclease. (351 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (469 aa)
AGI47153.1Metal-dependent hydrolases of the beta-lactamase superfamily I. (254 aa)
AGI47151.1Site-specific recombinase XerD. (323 aa)
AGI47148.1DNA modification methylase. (379 aa)
AGI47135.1Putative PilT protein; Vapc superfamily. (104 aa)
rpl7aeLSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (121 aa)
AGI47125.1Hypothetical protein. (459 aa)
AGI47102.1Transposase DDE domain protein. (518 aa)
AGI47069.1Eukaryotic-type DNA primase, large subunit. (244 aa)
Your Current Organism:
Thermoplasmatales archaeon BRNA1
NCBI taxonomy Id: 1054217
Other names: T. archaeon BRNA1
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