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Nwat_0192 Nwat_0192 Nwat_0436 Nwat_0436 ahcY ahcY metK metK Nwat_0514 Nwat_0514 cysC cysC cysQ cysQ Nwat_1090 Nwat_1090 Nwat_1189 Nwat_1189 cysI cysI metE metE Nwat_1481 Nwat_1481 trmJ trmJ Nwat_1811 Nwat_1811 metZ metZ cysS cysS Nwat_2120 Nwat_2120 Nwat_2121 Nwat_2121 Nwat_2122 Nwat_2122 Nwat_2123 Nwat_2123 Nwat_2124 Nwat_2124 Nwat_2125 Nwat_2125 Nwat_2265 Nwat_2265 Nwat_2313 Nwat_2313 Nwat_2502 Nwat_2502 Nwat_2789 Nwat_2789 metAS metAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Nwat_0192Rhodanese domain protein; KEGG: noc:Noc_0191 thiosulfate sulfurtransferase; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein. (270 aa)
Nwat_0436TIGRFAM: 5,10-methylenetetrahydrofolate reductase; KEGG: noc:Noc_2680 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (297 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (437 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (403 aa)
Nwat_0514PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: noc:Noc_2604 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (300 aa)
cysCAdenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (207 aa)
cysQ3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (274 aa)
Nwat_1090Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1232 aa)
Nwat_1189Sulfite reductase (NADPH) flavoprotein, alpha chain; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (610 aa)
cysISulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (579 aa)
metE5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (758 aa)
Nwat_1481KEGG: noc:Noc_1647 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase. (269 aa)
trmJRNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (246 aa)
Nwat_1811PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: noc:Noc_2006 putative oxidoreductase. (418 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (399 aa)
cysSTIGRFAM: cysteinyl-tRNA synthetase; KEGG: noc:Noc_2249 cysteine--tRNA ligase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; Belongs to the class-I aminoacyl-tRNA synthetase family. (495 aa)
Nwat_2120Hypothetical protein. (151 aa)
Nwat_2121Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (424 aa)
Nwat_2122KEGG: noc:Noc_2289 sulfate adenylyltransferase subunit 2; TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase. (301 aa)
Nwat_2123Adenylylsulfate reductase, thioredoxin dependent; Reduction of activated sulfate into sulfite. (237 aa)
Nwat_2124PFAM: protein of unknown function DUF81; KEGG: noc:Noc_2291 hypothetical protein. (266 aa)
Nwat_2125Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: noc:Noc_2292 transcriptional regulator CysB-like protein. (310 aa)
Nwat_2265KEGG: noc:Noc_0842 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (398 aa)
Nwat_2313KEGG: noc:Noc_0797 cysteine synthase B; TIGRFAM: cysteine synthase B; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. (296 aa)
Nwat_2502Rhodanese domain protein; KEGG: noc:Noc_0593 3-mercaptopyruvate sulfurtransferase; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein. (285 aa)
Nwat_2789KEGG: noc:Noc_2702 hypothetical protein. (281 aa)
metASHomoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. (358 aa)
Your Current Organism:
Nitrosococcus watsonii
NCBI taxonomy Id: 105559
Other names: N. watsonii C-113, Nitrosococcus sp. C-113, Nitrosococcus watsonii C-113, Nitrosococcus watsonii str. C-113, Nitrosococcus watsonii strain C-113
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