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ABD13206.1 ABD13206.1 ABD13205.1 ABD13205.1 ABD13165.1 ABD13165.1 aroA aroA ABD13102.1 ABD13102.1 lysA lysA dapB dapB dapA dapA dapF dapF ABD12816.1 ABD12816.1 mdh mdh ABD12568.1 ABD12568.1 aroC aroC aroK aroK aroB aroB nadA nadA ABD12441.1 ABD12441.1 ABD12370.1 ABD12370.1 ABD12369.1 ABD12369.1 ABD12349.1 ABD12349.1 ABD12283.1 ABD12283.1 ABD12271.1 ABD12271.1 ABD12181.1 ABD12181.1 ABD11831.1 ABD11831.1 ABD11444.1 ABD11444.1 ABD10078.1 ABD10078.1 ABD09821.1 ABD09821.1 ABD09820.1 ABD09820.1 aroQ aroQ ABD09650.1 ABD09650.1 asd asd ABD09573.1 ABD09573.1 fumC fumC ABD13752.1 ABD13752.1 ABD13403.1 ABD13403.1 ABD13753.1 ABD13753.1 ABD13751.1 ABD13751.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABD13206.12,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (280 aa)
ABD13205.1Succinyldiaminopimelate desuccinylase. (359 aa)
ABD13165.1Conserved hypothetical protein. (93 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (446 aa)
ABD13102.1Malate dehydrogenase. (408 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (486 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (275 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (352 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (302 aa)
ABD12816.1Amidohydrolase 3. (365 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
ABD12568.1Shikimate dehydrogenase. (346 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (394 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (225 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (362 aa)
nadAQuinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (407 aa)
ABD12441.13-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Belongs to the class-II DAHP synthase family. (466 aa)
ABD12370.1Glutamate synthase (NADH) large subunit. (1518 aa)
ABD12369.1Glutamate synthase (NADH) small subunit. (480 aa)
ABD12349.1Amidohydrolase. (489 aa)
ABD12283.1HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (310 aa)
ABD12271.1Ferredoxin-dependent glutamate synthase; Belongs to the glutamate synthase family. (529 aa)
ABD12181.1L-proline dehydrogenase. (309 aa)
ABD11831.1Chorismate mutase. (118 aa)
ABD11444.1Aspartate kinase; Belongs to the aspartokinase family. (408 aa)
ABD10078.1Peptidase M20D, amidohydrolase. (414 aa)
ABD09821.13-dehydroquinate synthase. (356 aa)
ABD09820.1Shikimate dehydrogenase. (273 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa)
ABD09650.1Aspartate kinase; Belongs to the aspartokinase family. (422 aa)
asdAspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (359 aa)
ABD09573.1Glutamate decarboxylase; Belongs to the group II decarboxylase family. (466 aa)
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)
ABD13752.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (155 aa)
ABD13403.1Diaminopimelate decarboxylase. (484 aa)
ABD13753.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (311 aa)
ABD13751.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (201 aa)
Your Current Organism:
Frankia casuarinae
NCBI taxonomy Id: 106370
Other names: CECT 9043, DSM 45818, F. casuarinae, Frankia casuarinae Nouioui et al. 2016, Frankia sp. BR, Frankia sp. CcI3, Frankia sp. Cg70.9, Frankia sp. Thr, strain CcI3
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