STRINGSTRING
MELS_0042 MELS_0042 MELS_0435 MELS_0435 dapF dapF MELS_0643 MELS_0643 MELS_0644 MELS_0644 MELS_0858 MELS_0858 MELS_0958 MELS_0958 thrB thrB dapB dapB asd asd dapA dapA MELS_1258 MELS_1258 MELS_1276 MELS_1276 MELS_1344 MELS_1344 MELS_1358 MELS_1358 MELS_1371 MELS_1371 MELS_1389 MELS_1389 MELS_1583 MELS_1583 MELS_1685 MELS_1685 MELS_1718 MELS_1718 ahcY ahcY metK metK MELS_1815 MELS_1815 MELS_1849 MELS_1849 MELS_2095 MELS_2095 MELS_2187 MELS_2187 MELS_2189 MELS_2189 metAA metAA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
MELS_0042LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily. (413 aa)
MELS_0435Aminotransferase. (407 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (279 aa)
MELS_0643Cysteine synthase. (314 aa)
MELS_0644Serine O-acetyltransferase. (232 aa)
MELS_0858Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (284 aa)
MELS_0958Homoserine dehydrogenase. (429 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (305 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (265 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (345 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (293 aa)
MELS_1258Diaminopimelate decarboxylase. (417 aa)
MELS_1276Threonine ammonia-lyase. (411 aa)
MELS_1344Aromatic amino acid beta-eliminating lyase/threonine aldolase. (344 aa)
MELS_1358PLP-dependent aminotransferase. (401 aa)
MELS_1371Putative uncharacterized protein. (401 aa)
MELS_1389Homocysteine S-methyltransferase. (316 aa)
MELS_1583Threonine synthase. (500 aa)
MELS_1685Cystathionine beta-lyase. (398 aa)
MELS_1718Cysteine synthase. (310 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (413 aa)
metKS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (396 aa)
MELS_1815Flavodoxins. (246 aa)
MELS_1849Homocysteine S-methyltransferase. (823 aa)
MELS_2095Aspartokinase; Belongs to the aspartokinase family. (407 aa)
MELS_2187Threonine aldolase. (349 aa)
MELS_2189O-acetylhomoserine aminocarboxypropyltransferase. (428 aa)
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (311 aa)
Your Current Organism:
Megasphaera elsdenii
NCBI taxonomy Id: 1064535
Other names: M. elsdenii DSM 20460, Megasphaera elsdenii ATCC 25940, Megasphaera elsdenii DSM 20460, Megasphaera elsdenii LC1, Megasphaera elsdenii str. DSM 20460, Megasphaera elsdenii strain DSM 20460
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