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| | NCAS0I01630 | Uncharacterized protein. (236 aa) |
| | NCAS0G01110 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (989 aa) |
| | NCAS0I01600 | Uncharacterized protein. (730 aa) |
| | NCAS0I01270 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa) |
| | NCAS0H03490 | Uncharacterized protein. (490 aa) |
| | NCAS0H02320 | ATPase_AAA_core domain-containing protein. (790 aa) |
| | NCAS0H01370 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (307 aa) |
| | NCAS0G02890 | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (299 aa) |
| | NCAS0G02740 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1412 aa) |
| | NCAS0G02620 | DNA polymerase. (1454 aa) |
| | NCAS0G01830 | WD_REPEATS_REGION domain-containing protein. (548 aa) |
| | NCAS0G01450 | AAA domain-containing protein. (569 aa) |
| | NCAS0B07380 | Protein kinase domain-containing protein. (527 aa) |
| | NCAS0B07270 | Uncharacterized protein. (263 aa) |
| | NCAS0B07020 | Uncharacterized protein. (405 aa) |
| | NCAS0B03980 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1184 aa) |
| | NCAS0B05920 | DNA polymerase. (1099 aa) |
| | NCAS0B05910 | Uncharacterized protein. (517 aa) |
| | NCAS0B05630 | DNA helicase; Belongs to the MCM family. (874 aa) |
| | NCAS0B05490 | Uncharacterized protein; Belongs to the MT-A70-like family. (557 aa) |
| | NCAS0E03350 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (908 aa) |
| | NCAS0E02270 | POLAc domain-containing protein. (1168 aa) |
| | NCAS0E01260 | Sld5 domain-containing protein. (203 aa) |
| | NCAS0E00980 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (387 aa) |
| | NCAS0E00680 | DNA helicase; Belongs to the MCM family. (1019 aa) |
| | NCAS0E00200 | Uncharacterized protein. (1122 aa) |
| | NCAS0D04700 | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (1038 aa) |
| | NCAS0D04180 | Uncharacterized protein. (1344 aa) |
| | NCAS0D03370 | Uncharacterized protein. (674 aa) |
| | NCAS0D02920 | DNA helicase; Belongs to the MCM family. (767 aa) |
| | NCAS0D02650 | DNA ligase. (950 aa) |
| | NCAS0D02090 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (753 aa) |
| | NCAS0D01980 | Uncharacterized protein. (473 aa) |
| | NCAS0D01420 | Uncharacterized protein. (1301 aa) |
| | NCAS0C04850 | Uncharacterized protein. (369 aa) |
| | NCAS0C04500 | Uncharacterized protein. (279 aa) |
| | NCAS0A06080 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (899 aa) |
| | NCAS0A06120 | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (543 aa) |
| | NCAS0A06340 | RIX1 domain-containing protein. (759 aa) |
| | NCAS0A06670 | ATP-dependent DNA helicase RRM3; 5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein- DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses. Required for timely replication of the telomere and subtelomeric DNA and for wild-type levels of telomeric silencing. Involved in DNA repair during stalled replication fork, regulation of fragile sites expression and essential for genome stability. Plays also a role in mtDNA replication. Has G- quadruplex (G4) unwindi [...] (761 aa) |
| | NCAS0A08270 | Uncharacterized protein. (602 aa) |
| | NCAS0A08300 | Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (322 aa) |
| | NCAS0A08310 | Uncharacterized protein. (424 aa) |
| | NCAS0A08670 | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (959 aa) |
| | NCAS0A08710 | AAA domain-containing protein. (321 aa) |
| | NCAS0A09230 | Uncharacterized protein. (170 aa) |
| | NCAS0A09310 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (215 aa) |
| | NCAS0A09420 | Uncharacterized protein. (784 aa) |
| | NCAS0A09890 | AAA domain-containing protein. (336 aa) |
| | NCAS0A10340 | Sld5 domain-containing protein. (205 aa) |
| | NCAS0A10570 | Uncharacterized protein. (225 aa) |
| | NCAS0A10760 | DBF4-type domain-containing protein. (573 aa) |
| | NCAS0A10930 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (679 aa) |
| | NCAS0A10960 | AAA domain-containing protein. (356 aa) |
| | NCAS0A11610 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (406 aa) |
| | NCAS0A11740 | Mcl1_mid domain-containing protein. (924 aa) |
| | NCAS0A12300 | AAA domain-containing protein. (350 aa) |
| | NCAS0A13190 | Uncharacterized protein. (1046 aa) |
| | NCAS0A13590 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (860 aa) |
| | NCAS0A13760 | Uncharacterized protein; Belongs to the AAA ATPase family. (825 aa) |
| | NCAS0A14110 | DNA ligase. (753 aa) |
| | NCAS0A14360 | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (392 aa) |
| | NCAS0A15050 | ORC4_C domain-containing protein. (583 aa) |
| | NCAS0A15060 | Uncharacterized protein. (1386 aa) |
| | NCAS0A15150 | DNA_pol_E_B domain-containing protein. (715 aa) |
| | NCAS0B05210 | Uncharacterized protein. (644 aa) |
| | NCAS0A04700 | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (524 aa) |
| | NCAS0C04200 | DNA helicase; Belongs to the MCM family. (929 aa) |
| | NCAS0C03720 | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1326 aa) |
| | NCAS0C03340 | Uncharacterized protein. (699 aa) |
| | NCAS0C03210 | Uncharacterized protein. (758 aa) |
| | NCAS0C02550 | ARID domain-containing protein. (1278 aa) |
| | NCAS0C02490 | Uncharacterized protein. (739 aa) |
| | NCAS0C01370 | Serine/threonine-protein kinase RAD53; Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. (799 aa) |
| | NCAS0C01250 | DNA polymerase. (1473 aa) |
| | NCAS0C00930 | Uncharacterized protein. (1703 aa) |
| | NCAS0B03850 | Uncharacterized protein. (588 aa) |
| | NCAS0B03750 | CBFD_NFYB_HMF domain-containing protein. (204 aa) |
| | NCAS0B02740 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (221 aa) |
| | NCAS0B02240 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (855 aa) |
| | NCAS0B01320 | Replication factor C subunit 1. (871 aa) |
| | NCAS0B00160 | Rtf2 domain-containing protein. (222 aa) |
| | NCAS0B09110 | MRC1 domain-containing protein. (1020 aa) |
| | NCAS0B08440 | Uncharacterized protein. (131 aa) |
| | NCAS0B04450 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (312 aa) |
| | NCAS0B08020 | Uncharacterized protein. (361 aa) |
| | NCAS0B07510 | Uncharacterized protein. (246 aa) |
| | NCAS0A04500 | Uncharacterized protein. (367 aa) |
| | NCAS0A04470 | Uncharacterized protein. (411 aa) |
| | NCAS0A02880 | Uncharacterized protein. (588 aa) |
| | NCAS0A02870 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (870 aa) |
| | NCAS0A02190 | Uncharacterized protein. (266 aa) |
| | NCAS0A01510 | ORC_WH_C domain-containing protein. (631 aa) |
| | NCAS0A01420 | Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (668 aa) |
| | NCAS0A00660 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2223 aa) |
| | NCAS0A00570 | TIMELESS domain-containing protein. (1232 aa) |
| | NCAS0G00500 | Uncharacterized protein. (245 aa) |
| | NCAS0G00220 | Zf-primase domain-containing protein. (592 aa) |
| | NCAS0G04070 | DNA helicase; Belongs to the MCM family. (985 aa) |
| | NCAS0F03720 | Uncharacterized protein. (1033 aa) |
| | NCAS0F03040 | Ipi1_N domain-containing protein. (326 aa) |
| | NCAS0F01640 | Endo/exonuclease/phosphatase domain-containing protein. (855 aa) |
| | NCAS0F01410 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (379 aa) |
| | NCAS0F01400 | Uncharacterized protein. (686 aa) |
| | NCAS0F01060 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa) |
| | NCAS0F00820 | AAA domain-containing protein. (739 aa) |
| | NCAS0E03580 | Uncharacterized protein; Belongs to the AAA ATPase family. (601 aa) |
| | NCAS0J02010 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (1001 aa) |
| | NCAS0J01870 | UvrD-like helicase ATP-binding domain-containing protein. (2314 aa) |
| | NCAS0J01370 | Uncharacterized protein. (739 aa) |
| | NCAS0J01120 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (613 aa) |
| | NCAS0J00990 | Uncharacterized protein. (1462 aa) |
| | NCAS0I03110 | Cell division control protein; Belongs to the CDC6/cdc18 family. (537 aa) |
| | NCAS0I02910 | Uncharacterized protein. (118 aa) |
| | NCAS0I02500 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (289 aa) |
| | NCAS0B07490 | Uncharacterized protein. (841 aa) |
| | NCAS0I02000 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2374 aa) |
| | NCAS0I01870 | Protein kinase domain-containing protein. (550 aa) |
