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NCAS0A04700 NCAS0A04700 NCAS0A00660 NCAS0A00660 NCAS0A03630 NCAS0A03630 NCAS0A05290 NCAS0A05290 NCAS0A05800 NCAS0A05800 NCAS0A06080 NCAS0A06080 NCAS0A07570 NCAS0A07570 NCAS0A08270 NCAS0A08270 NCAS0A08310 NCAS0A08310 NCAS0A08710 NCAS0A08710 NCAS0A09230 NCAS0A09230 NCAS0A09310 NCAS0A09310 NCAS0A09330 NCAS0A09330 NCAS0A09640 NCAS0A09640 NCAS0A09890 NCAS0A09890 NCAS0A10340 NCAS0A10340 NCAS0A10930 NCAS0A10930 NCAS0A10960 NCAS0A10960 NCAS0A11610 NCAS0A11610 NCAS0A11620 NCAS0A11620 NCAS0A12300 NCAS0A12300 NCAS0A13540 NCAS0A13540 NCAS0A14020 NCAS0A14020 NCAS0A14110 NCAS0A14110 NCAS0A15150 NCAS0A15150 NCAS0B05630 NCAS0B05630 NCAS0B05650 NCAS0B05650 NCAS0B05760 NCAS0B05760 NCAS0B05920 NCAS0B05920 NCAS0B07020 NCAS0B07020 NCAS0B07270 NCAS0B07270 NCAS0B07510 NCAS0B07510 NCAS0B01110 NCAS0B01110 NCAS0B01320 NCAS0B01320 NCAS0B02240 NCAS0B02240 NCAS0B02350 NCAS0B02350 NCAS0B03750 NCAS0B03750 NCAS0C02470 NCAS0C02470 NCAS0C02940 NCAS0C02940 NCAS0C04000 NCAS0C04000 NCAS0C04200 NCAS0C04200 NCAS0C04480 NCAS0C04480 NCAS0C05600 NCAS0C05600 NCAS0C05850 NCAS0C05850 NCAS0D01420 NCAS0D01420 NCAS0D01980 NCAS0D01980 NCAS0D02920 NCAS0D02920 NCAS0D04300 NCAS0D04300 NCAS0E00680 NCAS0E00680 NCAS0E00690 NCAS0E00690 NCAS0E00980 NCAS0E00980 NCAS0E00990 NCAS0E00990 NCAS0E01260 NCAS0E01260 NCAS0E01780 NCAS0E01780 NCAS0E02180 NCAS0E02180 NCAS0E03320 NCAS0E03320 NCAS0F00840 NCAS0F00840 NCAS0F01060 NCAS0F01060 NCAS0F01410 NCAS0F01410 NCAS0G04070 NCAS0G04070 NCAS0G01010 NCAS0G01010 NCAS0G02330 NCAS0G02330 NCAS0G02340 NCAS0G02340 NCAS0G02620 NCAS0G02620 NCAS0H00470 NCAS0H00470 NCAS0H00720 NCAS0H00720 NCAS0H02320 NCAS0H02320 NCAS0H03510 NCAS0H03510 NCAS0I00820 NCAS0I00820 NCAS0I01270 NCAS0I01270 NCAS0I02010 NCAS0I02010 NCAS0I02500 NCAS0I02500 NCAS0I03110 NCAS0I03110 NCAS0J01120 NCAS0J01120 NCAS0J02010 NCAS0J02010
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCAS0A04700DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (524 aa)
NCAS0A00660DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2223 aa)
NCAS0A03630Rad21_Rec8_N domain-containing protein. (656 aa)
NCAS0A05290Uncharacterized protein. (926 aa)
NCAS0A05800Reverse transcriptase Ty1/copia-type domain-containing protein. (319 aa)
NCAS0A06080Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (899 aa)
NCAS0A07570CYCLIN domain-containing protein; Belongs to the cyclin family. (539 aa)
NCAS0A08270Uncharacterized protein. (602 aa)
NCAS0A08310Uncharacterized protein. (424 aa)
NCAS0A08710AAA domain-containing protein. (321 aa)
NCAS0A09230Uncharacterized protein. (170 aa)
NCAS0A09310DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (215 aa)
NCAS0A09330Structural maintenance of chromosomes protein. (1227 aa)
NCAS0A09640Uncharacterized protein. (501 aa)
NCAS0A09890AAA domain-containing protein. (336 aa)
NCAS0A10340Sld5 domain-containing protein. (205 aa)
NCAS0A10930DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (679 aa)
NCAS0A10960AAA domain-containing protein. (356 aa)
NCAS0A11610Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (406 aa)
NCAS0A11620Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (479 aa)
NCAS0A12300AAA domain-containing protein. (350 aa)
NCAS0A13540Uncharacterized protein. (811 aa)
NCAS0A14020Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (404 aa)
NCAS0A14110DNA ligase. (753 aa)
NCAS0A15150DNA_pol_E_B domain-containing protein. (715 aa)
NCAS0B05630DNA helicase; Belongs to the MCM family. (874 aa)
NCAS0B05650Uncharacterized protein. (292 aa)
NCAS0B05760Integrase catalytic domain-containing protein. (177 aa)
NCAS0B05920DNA polymerase. (1099 aa)
NCAS0B07020Uncharacterized protein. (405 aa)
NCAS0B07270Uncharacterized protein. (263 aa)
NCAS0B07510Uncharacterized protein. (246 aa)
NCAS0B01110Zds_C domain-containing protein. (993 aa)
NCAS0B01320Replication factor C subunit 1. (871 aa)
NCAS0B02240DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (855 aa)
NCAS0B02350Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (296 aa)
NCAS0B03750CBFD_NFYB_HMF domain-containing protein. (204 aa)
NCAS0C02470Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (311 aa)
NCAS0C02940Ubiquitin-like domain-containing protein. (152 aa)
NCAS0C04000Structural maintenance of chromosomes protein. (1223 aa)
NCAS0C04200DNA helicase; Belongs to the MCM family. (929 aa)
NCAS0C04480RING-type domain-containing protein. (109 aa)
NCAS0C05600RT_RNaseH_2 domain-containing protein. (445 aa)
NCAS0C05850Uncharacterized protein. (388 aa)
NCAS0D01420Uncharacterized protein. (1301 aa)
NCAS0D01980Uncharacterized protein. (473 aa)
NCAS0D02920DNA helicase; Belongs to the MCM family. (767 aa)
NCAS0D04300G1/S-specific cyclin; G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition. (520 aa)
NCAS0E00680DNA helicase; Belongs to the MCM family. (1019 aa)
NCAS0E00690Reverse transcriptase Ty1/copia-type domain-containing protein. (247 aa)
NCAS0E00980Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (387 aa)
NCAS0E00990Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (432 aa)
NCAS0E01260Sld5 domain-containing protein. (203 aa)
NCAS0E01780SCD domain-containing protein. (1143 aa)
NCAS0E02180Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (465 aa)
NCAS0E03320Uncharacterized protein. (489 aa)
NCAS0F00840Uncharacterized protein. (1280 aa)
NCAS0F01060DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa)
NCAS0F01410Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (379 aa)
NCAS0G04070DNA helicase; Belongs to the MCM family. (985 aa)
NCAS0G01010G1/S-specific cyclin; G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition. (521 aa)
NCAS0G02330Integrase catalytic domain-containing protein. (657 aa)
NCAS0G02340Reverse transcriptase domain-containing protein. (195 aa)
NCAS0G02620DNA polymerase. (1454 aa)
NCAS0H00470Integrase catalytic domain-containing protein. (350 aa)
NCAS0H00720Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (423 aa)
NCAS0H02320ATPase_AAA_core domain-containing protein. (790 aa)
NCAS0H03510Uncharacterized protein. (1220 aa)
NCAS0I00820Uncharacterized protein. (579 aa)
NCAS0I01270Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
NCAS0I02010Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (141 aa)
NCAS0I02500DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (289 aa)
NCAS0I03110Cell division control protein; Belongs to the CDC6/cdc18 family. (537 aa)
NCAS0J01120Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (613 aa)
NCAS0J02010Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (1001 aa)
Your Current Organism:
Naumovozyma castellii
NCBI taxonomy Id: 1064592
Other names: N. castellii CBS 4309, Naumovozyma castellii CBS 4309
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