(61 nodes) Mixed, incl. U4/U6 x U5 tri-snRNP complex, and Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) network (Malus baccata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C1H46_021791	Uncharacterized protein. (323 aa)
	C1H46_045371	SEC63 domain-containing protein. (339 aa)
	C1H46_041714	Uncharacterized protein. (2180 aa)
	C1H46_040546	PROCT domain-containing protein. (75 aa)
	C1H46_040046	Uncharacterized protein. (560 aa)
	C1H46_039522	MPN domain-containing protein. (2347 aa)
	C1H46_039171	Uncharacterized protein. (568 aa)
	C1H46_037125	Nop domain-containing protein. (485 aa)
	C1H46_035151	Uncharacterized protein. (98 aa)
	C1H46_035154	Uncharacterized protein. (92 aa)
	C1H46_034039	Ubiquitin-like domain-containing protein. (73 aa)
	C1H46_033434	Uncharacterized protein. (1582 aa)
	C1H46_032139	Uncharacterized protein. (371 aa)
	C1H46_031795	WD_REPEATS_REGION domain-containing protein. (555 aa)
	C1H46_031430	Uncharacterized protein. (257 aa)
	C1H46_029193	TPR_REGION domain-containing protein. (468 aa)
	C1H46_028370	Uncharacterized protein. (572 aa)
	C1H46_028334	Tr-type G domain-containing protein. (988 aa)
	C1H46_027726	USP domain-containing protein. (676 aa)
	C1H46_026068	Tr-type G domain-containing protein. (988 aa)
	C1H46_025350	Uncharacterized protein. (934 aa)
	C1H46_024253	MPN domain-containing protein. (183 aa)
	C1H46_024252	Uncharacterized protein. (337 aa)
	C1H46_024050	Uncharacterized protein. (142 aa)
	C1H46_022243	Uncharacterized protein. (155 aa)
	C1H46_021958	Protein kinase domain-containing protein. (1018 aa)
	C1H46_021518	Nop domain-containing protein. (282 aa)
	C1H46_021517	Uncharacterized protein. (53 aa)
	C1H46_020853	OCRE domain-containing protein. (402 aa)
	C1H46_020813	Tr-type G domain-containing protein. (830 aa)
	LSM8-2	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (98 aa)
	C1H46_020009	Uncharacterized protein. (151 aa)
	C1H46_019449	SNRNP27 domain-containing protein. (176 aa)
	C1H46_019434	Sm domain-containing protein. (66 aa)
	C1H46_019122	Uncharacterized protein. (136 aa)
	C1H46_019084	Uncharacterized protein. (2143 aa)
	C1H46_018844	Uncharacterized protein; Belongs to the DEAD box helicase family. (718 aa)
	LSM5-2	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (88 aa)
	C1H46_017851	MPN domain-containing protein. (479 aa)
	C1H46_014569	Uncharacterized protein. (142 aa)
	C1H46_014085	Uncharacterized protein. (278 aa)
	C1H46_011483	Uncharacterized protein. (1092 aa)
	LSM3-2	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (97 aa)
	C1H46_009991	Small nuclear ribonucleoprotein Sm D2. (116 aa)
	C1H46_009503	Uncharacterized protein. (885 aa)
	C1H46_008505	WD_REPEATS_REGION domain-containing protein. (410 aa)
	C1H46_008612	SNRNP27 domain-containing protein. (203 aa)
	C1H46_008506	WD_REPEATS_REGION domain-containing protein. (375 aa)
	C1H46_006934	Uncharacterized protein. (107 aa)
	C1H46_007056	Uncharacterized protein. (131 aa)
	C1H46_006074	Sm domain-containing protein. (99 aa)
	C1H46_004103	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (203 aa)
	C1H46_004134	Uncharacterized protein. (150 aa)
	C1H46_003329	Uncharacterized protein. (795 aa)
	C1H46_003042	WD_REPEATS_REGION domain-containing protein. (344 aa)
	C1H46_002658	WD_REPEATS_REGION domain-containing protein. (542 aa)
	C1H46_001831	Uncharacterized protein. (296 aa)
	C1H46_001518	Uncharacterized protein. (810 aa)
	C1H46_001204	Uncharacterized protein. (58 aa)
	C1H46_000666	Sm-like protein LSM2; Component of LSM protein complexes, which are involved in RNA processing. (93 aa)
	C1H46_000379	Sm domain-containing protein. (56 aa)

Your Current Organism:

Malus baccata

NCBI taxonomy Id: 106549
Other names: M. baccata, Malus baccata (L.) Borkh., shan jing zi

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1H46_000379	C1H46_000666	A0A540NSG8	A0A540NRM2	Sm domain-containing protein.	Sm-like protein LSM2; Component of LSM protein complexes, which are involved in RNA processing.	0.998
C1H46_000379	C1H46_001204	A0A540NSG8	A0A540NRD5	Sm domain-containing protein.	Uncharacterized protein.	0.986
C1H46_000379	C1H46_001518	A0A540NSG8	A0A540NPB5	Sm domain-containing protein.	Uncharacterized protein.	0.991
C1H46_000379	C1H46_001831	A0A540NSG8	A0A540NNK2	Sm domain-containing protein.	Uncharacterized protein.	0.986
C1H46_000379	C1H46_002658	A0A540NSG8	A0A540NLB6	Sm domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.967
C1H46_000379	C1H46_003042	A0A540NSG8	A0A540NJU3	Sm domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.991
C1H46_000379	C1H46_003329	A0A540NSG8	A0A540NJ76	Sm domain-containing protein.	Uncharacterized protein.	0.972
C1H46_000379	C1H46_004103	A0A540NSG8	A0A540NGU7	Sm domain-containing protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.985
C1H46_000379	C1H46_004134	A0A540NSG8	A0A540NGY6	Sm domain-containing protein.	Uncharacterized protein.	0.986
C1H46_000379	C1H46_006074	A0A540NSG8	A0A540NB74	Sm domain-containing protein.	Sm domain-containing protein.	0.994
C1H46_000379	C1H46_006934	A0A540NSG8	A0A540N8T8	Sm domain-containing protein.	Uncharacterized protein.	0.986
C1H46_000379	C1H46_007056	A0A540NSG8	A0A540NA07	Sm domain-containing protein.	Uncharacterized protein.	0.981
C1H46_000379	C1H46_008505	A0A540NSG8	A0A540N438	Sm domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.967
C1H46_000379	C1H46_008506	A0A540NSG8	A0A540N5J3	Sm domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.967
C1H46_000379	C1H46_008612	A0A540NSG8	A0A540N5G6	Sm domain-containing protein.	SNRNP27 domain-containing protein.	0.961
C1H46_000379	C1H46_009503	A0A540NSG8	A0A540N2Z5	Sm domain-containing protein.	Uncharacterized protein.	0.972
C1H46_000379	C1H46_009991	A0A540NSG8	A0A540N002	Sm domain-containing protein.	Small nuclear ribonucleoprotein Sm D2.	0.999
C1H46_000379	C1H46_011483	A0A540NSG8	A0A540MVU7	Sm domain-containing protein.	Uncharacterized protein.	0.981
C1H46_000379	C1H46_014085	A0A540NSG8	A0A540MNI1	Sm domain-containing protein.	Uncharacterized protein.	0.851
C1H46_000379	C1H46_014569	A0A540NSG8	A0A540MM36	Sm domain-containing protein.	Uncharacterized protein.	0.981