(38 nodes) Protein neddylation, and Cullin network (Malus baccata)

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Your Input:
	C1H46_042776	CULLIN_2 domain-containing protein; Belongs to the cullin family. (726 aa)
	C1H46_040713	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (339 aa)
	C1H46_039831	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (90 aa)
	C1H46_039016	CULLIN_2 domain-containing protein; Belongs to the cullin family. (742 aa)
	C1H46_036733	Uncharacterized protein; Belongs to the SKP1 family. (207 aa)
	C1H46_035388	Cullin domain-containing protein; Belongs to the cullin family. (302 aa)
	C1H46_035386	Cullin domain-containing protein; Belongs to the cullin family. (302 aa)
	C1H46_032603	TIP120 domain-containing protein. (1071 aa)
	C1H46_031797	BTB domain-containing protein. (348 aa)
	C1H46_031800	Uncharacterized protein; Belongs to the NPH3 family. (469 aa)
	C1H46_031536	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (159 aa)
	C1H46_029286	Uncharacterized protein. (95 aa)
	C1H46_027823	UBIQUITIN_CONJUGAT_2 domain-containing protein. (159 aa)
	C1H46_027358	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (523 aa)
	C1H46_025788	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (486 aa)
	C1H46_023514	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (250 aa)
	C1H46_021741	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	C1H46_021744	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (181 aa)
	C1H46_021742	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (181 aa)
	C1H46_021365	UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa)
	C1H46_021125	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (323 aa)
	C1H46_021152	Uncharacterized protein. (60 aa)
	C1H46_021097	Uncharacterized protein. (121 aa)
	C1H46_020473	GUB_WAK_bind domain-containing protein. (262 aa)
	C1H46_020471	Cullin domain-containing protein; Belongs to the cullin family. (319 aa)
	C1H46_020468	Cullin domain-containing protein; Belongs to the cullin family. (444 aa)
	C1H46_018771	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (263 aa)
	C1H46_018901	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (267 aa)
	C1H46_016816	E2_bind domain-containing protein. (450 aa)
	C1H46_012587	Uncharacterized protein. (121 aa)
	C1H46_011708	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (333 aa)
	C1H46_011422	Cullin domain-containing protein; Belongs to the cullin family. (319 aa)
	C1H46_011421	Uncharacterized protein. (139 aa)
	C1H46_011703	CULLIN_2 domain-containing protein; Belongs to the cullin family. (727 aa)
	C1H46_009234	Uncharacterized protein; Belongs to the NPH3 family. (578 aa)
	C1H46_007171	UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa)
	C1H46_005277	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	C1H46_005276	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (181 aa)

Your Current Organism:

Malus baccata

NCBI taxonomy Id: 106549
Other names: M. baccata, Malus baccata (L.) Borkh., shan jing zi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1H46_005276	C1H46_007171	A0A540NES7	A0A540N7T6	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.886
C1H46_005276	C1H46_009234	A0A540NES7	A0A540N207	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein; Belongs to the NPH3 family.	0.718
C1H46_005276	C1H46_011421	A0A540NES7	A0A540MVW1	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein.	0.634
C1H46_005276	C1H46_011422	A0A540NES7	A0A540MVV2	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Cullin domain-containing protein; Belongs to the cullin family.	0.634
C1H46_005276	C1H46_011703	A0A540NES7	A0A540MWK6	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.634
C1H46_005276	C1H46_011708	A0A540NES7	A0A540MV32	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	0.718
C1H46_005276	C1H46_016816	A0A540NES7	A0A540MFN1	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	E2_bind domain-containing protein.	0.928
C1H46_005276	C1H46_018771	A0A540NES7	A0A540MA40	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	0.718
C1H46_005276	C1H46_018901	A0A540NES7	A0A540MAI7	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	0.718
C1H46_005276	C1H46_020468	A0A540NES7	A0A540M5X4	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Cullin domain-containing protein; Belongs to the cullin family.	0.634
C1H46_005276	C1H46_020471	A0A540NES7	A0A540M5W8	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Cullin domain-containing protein; Belongs to the cullin family.	0.634
C1H46_005276	C1H46_020473	A0A540NES7	A0A540M584	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	GUB_WAK_bind domain-containing protein.	0.634
C1H46_005276	C1H46_021125	A0A540NES7	A0A540M393	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	0.718
C1H46_005276	C1H46_021152	A0A540NES7	A0A540M3C1	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein.	0.634
C1H46_005276	C1H46_021365	A0A540NES7	A0A540M2T5	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.886
C1H46_005276	C1H46_023514	A0A540NES7	A0A540LWM5	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	0.718
C1H46_005276	C1H46_025788	A0A540NES7	A0A540LQ94	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	0.901
C1H46_005276	C1H46_027358	A0A540NES7	A0A540LKS8	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	0.901
C1H46_005276	C1H46_027823	A0A540NES7	A0A540LJG1	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.887
C1H46_005276	C1H46_029286	A0A540NES7	A0A540LFD9	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein.	0.639