STRINGSTRING
C1H46_016337 C1H46_016337 C1H46_003499 C1H46_003499 MCM7-3 MCM7-3 MCM7-2 MCM7-2 C1H46_030607 C1H46_030607 C1H46_030942 C1H46_030942 C1H46_031333 C1H46_031333 C1H46_031701 C1H46_031701 C1H46_031717 C1H46_031717 C1H46_033244 C1H46_033244 C1H46_034130 C1H46_034130 C1H46_034773 C1H46_034773 C1H46_034999 C1H46_034999 C1H46_041193 C1H46_041193 C1H46_035369 C1H46_035369 C1H46_036172 C1H46_036172 C1H46_036258 C1H46_036258 C1H46_036395 C1H46_036395 C1H46_036987 C1H46_036987 C1H46_037185 C1H46_037185 TOP6B TOP6B C1H46_037551 C1H46_037551 C1H46_037498 C1H46_037498 C1H46_037552 C1H46_037552 C1H46_038744 C1H46_038744 C1H46_038745 C1H46_038745 C1H46_038810 C1H46_038810 C1H46_038929 C1H46_038929 C1H46_039062 C1H46_039062 C1H46_039388 C1H46_039388 C1H46_039887 C1H46_039887 C1H46_039882 C1H46_039882 C1H46_021509 C1H46_021509 C1H46_041271 C1H46_041271 C1H46_041808 C1H46_041808 C1H46_041757 C1H46_041757 C1H46_042408 C1H46_042408 C1H46_042643 C1H46_042643 C1H46_044189 C1H46_044189 C1H46_044243 C1H46_044243 C1H46_044510 C1H46_044510 C1H46_044661 C1H46_044661 C1H46_044851 C1H46_044851 C1H46_045334 C1H46_045334 MCM7 MCM7 C1H46_021563 C1H46_021563 C1H46_022588 C1H46_022588 C1H46_022843 C1H46_022843 C1H46_022777 C1H46_022777 C1H46_022862 C1H46_022862 C1H46_023085 C1H46_023085 C1H46_024105 C1H46_024105 C1H46_024121 C1H46_024121 C1H46_025201 C1H46_025201 C1H46_025107 C1H46_025107 C1H46_025203 C1H46_025203 C1H46_025860 C1H46_025860 C1H46_026320 C1H46_026320 C1H46_026623 C1H46_026623 C1H46_026946 C1H46_026946 C1H46_026950 C1H46_026950 C1H46_026947 C1H46_026947 C1H46_026954 C1H46_026954 C1H46_026943 C1H46_026943 C1H46_026942 C1H46_026942 C1H46_027798 C1H46_027798 C1H46_027647 C1H46_027647 C1H46_027791 C1H46_027791 C1H46_028319 C1H46_028319 C1H46_028777 C1H46_028777 C1H46_030015 C1H46_030015 C1H46_029865 C1H46_029865 C1H46_029866 C1H46_029866 C1H46_030361 C1H46_030361 MCM7-4 MCM7-4 C1H46_009913 C1H46_009913 C1H46_009972 C1H46_009972 C1H46_009971 C1H46_009971 C1H46_010912 C1H46_010912 C1H46_010911 C1H46_010911 C1H46_010953 C1H46_010953 C1H46_011016 C1H46_011016 C1H46_012802 C1H46_012802 C1H46_012816 C1H46_012816 C1H46_012982 C1H46_012982 C1H46_013899 C1H46_013899 C1H46_013816 C1H46_013816 C1H46_014086 C1H46_014086 C1H46_014026 C1H46_014026 C1H46_014359 C1H46_014359 C1H46_009900 C1H46_009900 C1H46_014521 C1H46_014521 C1H46_014562 C1H46_014562 C1H46_014800 C1H46_014800 C1H46_014978 C1H46_014978 C1H46_015107 C1H46_015107 C1H46_015826 C1H46_015826 C1H46_016702 C1H46_016702 C1H46_016829 C1H46_016829 C1H46_017062 C1H46_017062 C1H46_017672 C1H46_017672 C1H46_017459 C1H46_017459 C1H46_018727 C1H46_018727 C1H46_019564 C1H46_019564 C1H46_020879 C1H46_020879 C1H46_020725 C1H46_020725 C1H46_020938 C1H46_020938 C1H46_020839 C1H46_020839 C1H46_020939 C1H46_020939 C1H46_021282 C1H46_021282 C1H46_003016 C1H46_003016 C1H46_002413 C1H46_002413 C1H46_001339 C1H46_001339 TOP6A TOP6A C1H46_001277 C1H46_001277 C1H46_009602 C1H46_009602 C1H46_009899 C1H46_009899 C1H46_009287 C1H46_009287 C1H46_008848 C1H46_008848 C1H46_008075 C1H46_008075 C1H46_007376 C1H46_007376 C1H46_007292 C1H46_007292 C1H46_006783 C1H46_006783 C1H46_005450 C1H46_005450 C1H46_004421 C1H46_004421 C1H46_004257 C1H46_004257
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C1H46_016337Uncharacterized protein. (1111 aa)
C1H46_003499Uncharacterized protein. (667 aa)
MCM7-3DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (197 aa)
MCM7-2DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (594 aa)
C1H46_030607Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (646 aa)
C1H46_030942Uncharacterized protein. (2192 aa)
C1H46_031333Uncharacterized protein. (1066 aa)
C1H46_031701ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (934 aa)
C1H46_031717TOP4c domain-containing protein. (822 aa)
C1H46_033244DNA helicase; Belongs to the MCM family. (1067 aa)
C1H46_034130AAA_23 domain-containing protein. (1452 aa)
C1H46_034773Uncharacterized protein. (78 aa)
C1H46_034999Uncharacterized protein. (826 aa)
C1H46_041193Uncharacterized protein. (141 aa)
C1H46_035369DNA helicase; Belongs to the MCM family. (929 aa)
C1H46_036172DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (886 aa)
C1H46_036258DNA helicase; Belongs to the MCM family. (929 aa)
C1H46_036395Uncharacterized protein. (665 aa)
C1H46_036987Uncharacterized protein. (740 aa)
C1H46_037185HSA domain-containing protein. (372 aa)
TOP6BDNA topoisomerase 6 subunit B; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP; Belongs to the TOP6B family. (627 aa)
C1H46_037551DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner. (744 aa)
C1H46_037498Uncharacterized protein. (128 aa)
C1H46_037552DNA_gyraseB_C domain-containing protein. (62 aa)
C1H46_038744DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (471 aa)
C1H46_038745DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (568 aa)
C1H46_038810UBA domain-containing protein. (588 aa)
C1H46_038929Uncharacterized protein. (782 aa)
C1H46_039062Uncharacterized protein. (85 aa)
C1H46_039388Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (869 aa)
C1H46_039887Uncharacterized protein. (317 aa)
C1H46_039882DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (835 aa)
C1H46_021509RuvB-like helicase; Belongs to the RuvB family. (463 aa)
C1H46_041271Uncharacterized protein. (256 aa)
C1H46_041808DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (883 aa)
C1H46_041757RuvB-like helicase; Belongs to the RuvB family. (463 aa)
C1H46_042408Helicase ATP-binding domain-containing protein. (296 aa)
C1H46_042643Uncharacterized protein. (962 aa)
C1H46_044189Uncharacterized protein. (138 aa)
C1H46_044243Helicase ATP-binding domain-containing protein. (372 aa)
C1H46_044510Uncharacterized protein. (62 aa)
C1H46_044661Helicase C-terminal domain-containing protein. (216 aa)
C1H46_044851Uncharacterized protein. (761 aa)
C1H46_045334T2SP_E domain-containing protein. (186 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (57 aa)
C1H46_021563Helicase ATP-binding domain-containing protein. (573 aa)
C1H46_022588ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (605 aa)
C1H46_022843Helitron_like_N domain-containing protein. (303 aa)
C1H46_022777DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1470 aa)
C1H46_022862Helicase ATP-binding domain-containing protein. (947 aa)
C1H46_023085Uncharacterized protein. (198 aa)
C1H46_024105ATP-dependent DNA helicase; Belongs to the helicase family. (530 aa)
C1H46_024121Uncharacterized protein. (1098 aa)
C1H46_025201Uncharacterized protein. (100 aa)
C1H46_025107SAP domain-containing protein. (629 aa)
C1H46_025203Uncharacterized protein. (530 aa)
C1H46_025860Uncharacterized protein. (1744 aa)
C1H46_026320MCM domain-containing protein; Belongs to the MCM family. (1111 aa)
C1H46_026623Uncharacterized protein. (473 aa)
C1H46_026946TOPRIM_C domain-containing protein. (285 aa)
C1H46_026950DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1017 aa)
C1H46_026947TOP4c domain-containing protein. (182 aa)
C1H46_026954TOP4c domain-containing protein. (201 aa)
C1H46_026943Uncharacterized protein. (159 aa)
C1H46_026942Uncharacterized protein. (691 aa)
C1H46_027798Toprim domain-containing protein. (394 aa)
C1H46_027647Toprim domain-containing protein. (1088 aa)
C1H46_027791ATP-dependent DNA helicase; Belongs to the helicase family. (451 aa)
C1H46_028319DNA helicase; Belongs to the MCM family. (757 aa)
C1H46_028777Uncharacterized protein. (1273 aa)
C1H46_030015Uncharacterized protein. (464 aa)
C1H46_029865DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (598 aa)
C1H46_029866Topo_C_assoc domain-containing protein. (64 aa)
C1H46_030361Uncharacterized protein. (210 aa)
MCM7-4DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (137 aa)
C1H46_009913RQC domain-containing protein. (187 aa)
C1H46_009972HELICc2 domain-containing protein. (415 aa)
C1H46_009971Helicase ATP-binding domain-containing protein. (623 aa)
C1H46_010912Uncharacterized protein. (289 aa)
C1H46_010911Uncharacterized protein. (535 aa)
C1H46_010953Uncharacterized protein. (62 aa)
C1H46_011016ATP-dependent DNA helicase 2 subunit KU80; Single-stranded DNA-dependent ATP-dependent helicase. (682 aa)
C1H46_012802Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (635 aa)
C1H46_012816Uncharacterized protein. (2085 aa)
C1H46_012982Uncharacterized protein. (680 aa)
C1H46_013899Uncharacterized protein. (208 aa)
C1H46_013816Toprim domain-containing protein. (989 aa)
C1H46_014086Uncharacterized protein. (1015 aa)
C1H46_014026DNA helicase; Belongs to the MCM family. (1407 aa)
C1H46_014359Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (604 aa)
C1H46_009900Uncharacterized protein. (284 aa)
C1H46_014521Uncharacterized protein. (109 aa)
C1H46_014562HD domain-containing protein. (292 aa)
C1H46_014800Uncharacterized protein. (2199 aa)
C1H46_014978DNA helicase; Belongs to the MCM family. (692 aa)
C1H46_015107Helicase ATP-binding domain-containing protein. (536 aa)
C1H46_015826Uncharacterized protein. (1044 aa)
C1H46_016702Helitron_like_N domain-containing protein. (554 aa)
C1H46_016829Helicase C-terminal domain-containing protein. (868 aa)
C1H46_017062Uncharacterized protein. (261 aa)
C1H46_017672Uncharacterized protein. (940 aa)
C1H46_017459Helicase C-terminal domain-containing protein. (398 aa)
C1H46_018727DNA helicase; Belongs to the MCM family. (817 aa)
C1H46_019564Dna2 domain-containing protein. (591 aa)
C1H46_020879MCM domain-containing protein; Belongs to the MCM family. (426 aa)
C1H46_020725ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (766 aa)
C1H46_020938Uncharacterized protein. (786 aa)
C1H46_020839DNA helicase; Belongs to the MCM family. (754 aa)
C1H46_020939Uncharacterized protein. (646 aa)
C1H46_021282DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (410 aa)
C1H46_003016RuvB-like helicase; Belongs to the RuvB family. (559 aa)
C1H46_002413SF4 helicase domain-containing protein. (208 aa)
C1H46_001339DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (831 aa)
TOP6ADNA topoisomerase 6 subunit A; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (421 aa)
C1H46_001277MCM domain-containing protein; Belongs to the MCM family. (749 aa)
C1H46_009602Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (646 aa)
C1H46_009899TOP4c domain-containing protein. (648 aa)
C1H46_009287ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (901 aa)
C1H46_008848TOP4c domain-containing protein. (253 aa)
C1H46_008075MCM domain-containing protein; Belongs to the MCM family. (749 aa)
C1H46_007376Uncharacterized protein. (500 aa)
C1H46_007292Helicase C-terminal domain-containing protein. (567 aa)
C1H46_006783Helicase ATP-binding domain-containing protein. (1274 aa)
C1H46_005450Uncharacterized protein. (1337 aa)
C1H46_004421Uncharacterized protein. (373 aa)
C1H46_004257Uncharacterized protein. (85 aa)
Your Current Organism:
Malus baccata
NCBI taxonomy Id: 106549
Other names: M. baccata, Malus baccata (L.) Borkh., shan jing zi
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