(76 nodes) Steroid biosynthesis network (Malus baccata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C1H46_016404	Methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family. (360 aa)
	C1H46_036256	C2 domain-containing protein. (292 aa)
	C1H46_035029	Uncharacterized protein; Belongs to the cytochrome P450 family. (489 aa)
	C1H46_034449	SE domain-containing protein. (538 aa)
	C1H46_034320	SE domain-containing protein. (537 aa)
	C1H46_033580	Abhydro_lipase domain-containing protein. (699 aa)
	C1H46_033252	Uncharacterized protein; Belongs to the cytochrome P450 family. (503 aa)
	C1H46_033178	SE domain-containing protein. (529 aa)
	C1H46_033176	SE domain-containing protein. (528 aa)
	C1H46_031423	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (410 aa)
	C1H46_030192	SQHop_cyclase_C domain-containing protein. (548 aa)
	C1H46_029646	S-acyltransferase; Belongs to the DHHC palmitoyltransferase family. (307 aa)
	C1H46_029336	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (281 aa)
	C1H46_029207	Uncharacterized protein. (448 aa)
	C1H46_029205	Uncharacterized protein. (462 aa)
	C1H46_028603	S5A_REDUCTASE domain-containing protein. (281 aa)
	C1H46_027129	SE domain-containing protein. (353 aa)
	C1H46_025086	PNPLA domain-containing protein. (501 aa)
	C1H46_025087	Uncharacterized protein. (262 aa)
	C1H46_024856	Uncharacterized protein. (150 aa)
	C1H46_024025	Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] (823 aa)
	C1H46_023401	Uncharacterized protein. (469 aa)
	C1H46_022782	Methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family. (440 aa)
	C1H46_019931	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (782 aa)
	C1H46_018492	Uncharacterized protein. (70 aa)
	C1H46_018300	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (272 aa)
	C1H46_036255	EXPERA domain-containing protein. (230 aa)
	C1H46_015307	Uncharacterized protein. (295 aa)
	C1H46_014993	Uncharacterized protein. (366 aa)
	C1H46_014822	Abhydro_lipase domain-containing protein. (196 aa)
	C1H46_014542	FAD-binding PCMH-type domain-containing protein. (568 aa)
	C1H46_014244	Abhydro_lipase domain-containing protein. (195 aa)
	C1H46_014242	Uncharacterized protein. (527 aa)
	C1H46_013965	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (289 aa)
	C1H46_013387	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (186 aa)
	C1H46_012942	Reticulon-like protein. (560 aa)
	C1H46_011932	SE domain-containing protein. (502 aa)
	C1H46_011931	SE domain-containing protein. (238 aa)
	C1H46_011933	SE domain-containing protein. (584 aa)
	C1H46_011022	S-acyltransferase; Belongs to the DHHC palmitoyltransferase family. (300 aa)
	C1H46_010092	Uncharacterized protein. (354 aa)
	C1H46_009213	Reticulon-like protein. (560 aa)
	C1H46_008529	PNPLA domain-containing protein. (835 aa)
	C1H46_008400	PNPLA domain-containing protein. (845 aa)
	C1H46_008366	Uncharacterized protein. (109 aa)
	C1H46_008364	Uncharacterized protein. (987 aa)
	C1H46_006852	Methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family. (360 aa)
	C1H46_006670	Uncharacterized protein. (190 aa)
	C1H46_006669	AB hydrolase-1 domain-containing protein. (314 aa)
	C1H46_005823	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (770 aa)
	C1H46_005826	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (618 aa)
	C1H46_004443	Uncharacterized protein. (239 aa)
	C1H46_004520	S5A_REDUCTASE domain-containing protein. (308 aa)
	C1H46_002296	Uncharacterized protein. (530 aa)
	C1H46_001896	Uncharacterized protein. (449 aa)
	C1H46_001748	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (297 aa)
	C1H46_001343	SAM_MT_ERG6_SMT domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family. (326 aa)
	C1H46_000261	Uncharacterized protein. (535 aa)
	C1H46_036280	EXPERA domain-containing protein. (230 aa)
	C1H46_036279	C2 domain-containing protein. (315 aa)
	C1H46_036507	Uncharacterized protein; Belongs to the cytochrome P450 family. (489 aa)
	C1H46_039700	Uncharacterized protein. (99 aa)
	C1H46_040699	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (414 aa)
	C1H46_042119	Uncharacterized protein. (312 aa)
	C1H46_042116	Uncharacterized protein. (301 aa)
	C1H46_042117	Uncharacterized protein. (241 aa)
	C1H46_042830	Uncharacterized protein. (94 aa)
	C1H46_042828	SE domain-containing protein. (147 aa)
	C1H46_043921	Uncharacterized protein. (993 aa)
	C1H46_043922	Reticulon-like protein. (589 aa)
	C1H46_044062	Uncharacterized protein. (369 aa)
	C1H46_044782	Uncharacterized protein. (104 aa)
	C1H46_044871	Uncharacterized protein. (264 aa)
	C1H46_045058	Uncharacterized protein. (113 aa)
	C1H46_045347	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (106 aa)
	C1H46_045479	SE domain-containing protein. (231 aa)

Your Current Organism:

Malus baccata

NCBI taxonomy Id: 106549
Other names: M. baccata, Malus baccata (L.) Borkh., shan jing zi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1H46_000261	C1H46_001748	A0A540NTH7	A0A540NNC5	Uncharacterized protein.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.916
C1H46_000261	C1H46_001896	A0A540NTH7	A0A540NNB6	Uncharacterized protein.	Uncharacterized protein.	0.960
C1H46_000261	C1H46_005823	A0A540NTH7	A0A540NBU3	Uncharacterized protein.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.962
C1H46_000261	C1H46_005826	A0A540NTH7	A0A540NDE4	Uncharacterized protein.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.971
C1H46_000261	C1H46_008366	A0A540NTH7	A0A540N4R9	Uncharacterized protein.	Uncharacterized protein.	0.792
C1H46_000261	C1H46_009213	A0A540NTH7	A0A540N2J8	Uncharacterized protein.	Reticulon-like protein.	0.792
C1H46_000261	C1H46_010092	A0A540NTH7	A0A540MZS5	Uncharacterized protein.	Uncharacterized protein.	0.711
C1H46_000261	C1H46_012942	A0A540NTH7	A0A540MRQ6	Uncharacterized protein.	Reticulon-like protein.	0.792
C1H46_000261	C1H46_013387	A0A540NTH7	A0A540MPX4	Uncharacterized protein.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.916
C1H46_000261	C1H46_013965	A0A540NTH7	A0A540MNS7	Uncharacterized protein.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.916
C1H46_000261	C1H46_014542	A0A540NTH7	A0A540MM20	Uncharacterized protein.	FAD-binding PCMH-type domain-containing protein.	0.435
C1H46_000261	C1H46_014993	A0A540NTH7	A0A540MKV2	Uncharacterized protein.	Uncharacterized protein.	0.980
C1H46_000261	C1H46_015307	A0A540NTH7	A0A540MJZ4	Uncharacterized protein.	Uncharacterized protein.	0.792
C1H46_000261	C1H46_018300	A0A540NTH7	A0A540MBE1	Uncharacterized protein.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.773
C1H46_000261	C1H46_018492	A0A540NTH7	A0A540MAZ2	Uncharacterized protein.	Uncharacterized protein.	0.939
C1H46_000261	C1H46_019931	A0A540NTH7	A0A540M6R0	Uncharacterized protein.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.961
C1H46_000261	C1H46_023401	A0A540NTH7	A0A540LX07	Uncharacterized protein.	Uncharacterized protein.	0.792
C1H46_000261	C1H46_024025	A0A540NTH7	A0A540LVH5	Uncharacterized protein.	Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...]	0.435
C1H46_000261	C1H46_029205	A0A540NTH7	A0A540LFP4	Uncharacterized protein.	Uncharacterized protein.	0.955
C1H46_000261	C1H46_029207	A0A540NTH7	A0A540LFN8	Uncharacterized protein.	Uncharacterized protein.	0.951