STRINGSTRING
orc5 orc5 mcm5 mcm5 cdc7 cdc7 orc3 orc3 cdc6 cdc6 mcm7 mcm7 cdc45 cdc45 LOC112436452 LOC112436452 orc2 orc2 mcm10 mcm10 orc4 orc4 mcm2 mcm2 orc1 orc1 cdt1 cdt1 dbf4 dbf4 mcm3 mcm3 mcm4 mcm4 LOC101476670 LOC101476670 mcm9 mcm9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
orc5Origin recognition complex, subunit 5. (445 aa)
mcm5DNA helicase; Belongs to the MCM family. (737 aa)
cdc7Cell division cycle 7 homolog (S. cerevisiae). (611 aa)
orc3Origin recognition complex, subunit 3. (720 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (602 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (740 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (568 aa)
LOC112436452DNA helicase; Belongs to the MCM family. (828 aa)
orc2Uncharacterized protein. (576 aa)
mcm10Minichromosome maintenance 10 replication initiation factor. (896 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa)
mcm2DNA helicase; Belongs to the MCM family. (886 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (899 aa)
cdt1Chromatin licensing and DNA replication factor 1. (599 aa)
dbf4DBF4 zinc finger. (613 aa)
mcm3DNA helicase; Belongs to the MCM family. (811 aa)
mcm4DNA helicase; Belongs to the MCM family. (860 aa)
LOC101476670DNA helicase; Belongs to the MCM family. (828 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1169 aa)
Your Current Organism:
Maylandia zebra
NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna
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