(13 nodes) Beta-catenin destruction complex, and WTX protein network (Maylandia zebra)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gsk3b	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (421 aa)
	apc2	APC regulator of WNT signaling pathway 2. (2516 aa)
	LOC101464051	Axin 2 (conductin, axil). (841 aa)
	ENSMZEP00005009977	APC membrane recruitment protein 1. (847 aa)
	AXIN2	Axin 2. (793 aa)
	LOC101472703	Uncharacterized protein. (883 aa)
	ENSMZEP00005022670	Glycogen synthase kinase binding protein. (162 aa)
	csnk1a1	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily. (353 aa)
	LOC101487071	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
	axin1	Axin 1. (825 aa)
	Apc	APC_N_CC domain-containing protein. (220 aa)
	LOC101472422	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (438 aa)
	dvl1	Dishevelled segment polarity protein 1a. (722 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	Apc	ENSMZEP00005015032	ENSMZEP00005031072	Axin 2.	APC_N_CC domain-containing protein.	0.984
AXIN2	ENSMZEP00005009977	ENSMZEP00005015032	ENSMZEP00005009977	Axin 2.	APC membrane recruitment protein 1.	0.794
AXIN2	ENSMZEP00005022670	ENSMZEP00005015032	ENSMZEP00005022670	Axin 2.	Glycogen synthase kinase binding protein.	0.515
AXIN2	LOC101472422	ENSMZEP00005015032	ENSMZEP00005034787	Axin 2.	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	0.824
AXIN2	LOC101487071	ENSMZEP00005015032	ENSMZEP00005024692	Axin 2.	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	0.824
AXIN2	apc2	ENSMZEP00005015032	ENSMZEP00005003894	Axin 2.	APC regulator of WNT signaling pathway 2.	0.984
AXIN2	csnk1a1	ENSMZEP00005015032	ENSMZEP00005023147	Axin 2.	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.	0.986
AXIN2	dvl1	ENSMZEP00005015032	ENSMZEP00005035204	Axin 2.	Dishevelled segment polarity protein 1a.	0.974
AXIN2	gsk3b	ENSMZEP00005015032	ENSMZEP00005001821	Axin 2.	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.	0.985
Apc	AXIN2	ENSMZEP00005031072	ENSMZEP00005015032	APC_N_CC domain-containing protein.	Axin 2.	0.984
Apc	ENSMZEP00005009977	ENSMZEP00005031072	ENSMZEP00005009977	APC_N_CC domain-containing protein.	APC membrane recruitment protein 1.	0.930
Apc	ENSMZEP00005022670	ENSMZEP00005031072	ENSMZEP00005022670	APC_N_CC domain-containing protein.	Glycogen synthase kinase binding protein.	0.587
Apc	LOC101464051	ENSMZEP00005031072	ENSMZEP00005004394	APC_N_CC domain-containing protein.	Axin 2 (conductin, axil).	0.984
Apc	LOC101472422	ENSMZEP00005031072	ENSMZEP00005034787	APC_N_CC domain-containing protein.	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	0.847
Apc	LOC101472703	ENSMZEP00005031072	ENSMZEP00005018244	APC_N_CC domain-containing protein.	Uncharacterized protein.	0.984
Apc	LOC101487071	ENSMZEP00005031072	ENSMZEP00005024692	APC_N_CC domain-containing protein.	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	0.847
Apc	apc2	ENSMZEP00005031072	ENSMZEP00005003894	APC_N_CC domain-containing protein.	APC regulator of WNT signaling pathway 2.	0.900
Apc	axin1	ENSMZEP00005031072	ENSMZEP00005030195	APC_N_CC domain-containing protein.	Axin 1.	0.984
Apc	csnk1a1	ENSMZEP00005031072	ENSMZEP00005023147	APC_N_CC domain-containing protein.	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.	0.792
Apc	dvl1	ENSMZEP00005031072	ENSMZEP00005035204	APC_N_CC domain-containing protein.	Dishevelled segment polarity protein 1a.	0.955