STRINGSTRING
prkra prkra znfx1 znfx1 tarbp2 tarbp2 tnrc6a tnrc6a LOC101466533 LOC101466533 LOC101466039 LOC101466039 LOC101480651 LOC101480651 tsnax tsnax LOC101465200 LOC101465200 stau1 stau1 adar adar dicer1 dicer1 LOC101485294 LOC101485294 dgcr8 dgcr8 tsn tsn drosha drosha stau2 stau2 LOC101482087 LOC101482087 LOC101469049 LOC101469049 LOC101466128 LOC101466128
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
prkraProtein kinase, interferon-inducible double stranded RNA dependent activator. (290 aa)
znfx1Zinc finger, NFX1-type containing 1. (1955 aa)
tarbp2RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (345 aa)
tnrc6aTrinucleotide repeat containing adaptor 6A. (1840 aa)
LOC101466533Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (860 aa)
LOC101466039Argonaute RISC component 1; Belongs to the argonaute family. (858 aa)
LOC101480651Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (870 aa)
tsnaxTranslin-associated factor X. (283 aa)
LOC101465200Trinucleotide repeat containing adaptor 6C1. (1815 aa)
stau1Staufen double-stranded RNA binding protein 1. (691 aa)
adarAdenosine deaminase RNA specific. (1344 aa)
dicer1Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1906 aa)
LOC101485294Adenosine deaminase RNA specific B1b. (747 aa)
dgcr8DGCR8 microprocessor complex subunit. (782 aa)
tsnTranslin. (268 aa)
droshaDrosha ribonuclease III. (1362 aa)
stau2Staufen double-stranded RNA binding protein 2. (667 aa)
LOC101482087Trinucleotide repeat containing adaptor 6C2. (1858 aa)
LOC101469049Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (867 aa)
LOC101466128Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (944 aa)
Your Current Organism:
Maylandia zebra
NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna
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