(105 nodes) Fatty acid beta-oxidation, and Valine, leucine and isoleucine degradation network (Maylandia zebra)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	amacr	Alpha-methylacyl-CoA racemase. (382 aa)
	LOC101480240	Uncharacterized protein. (107 aa)
	LOC101479026	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa)
	pex6	Peroxisomal biogenesis factor 6. (1049 aa)
	acox1	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
	acadsb	Acyl-CoA dehydrogenase short/branched chain. (433 aa)
	etfdh	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (619 aa)
	acss3	Acyl-CoA synthetase short chain family member 3. (694 aa)
	GCDH	Glutaryl-CoA dehydrogenase b. (440 aa)
	pex5l	Peroxisomal biogenesis factor 5-like a. (507 aa)
	ENSMZEP00005002963	Uncharacterized protein. (173 aa)
	ENSMZEP00005003466	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (331 aa)
	phyhd1	Phytanoyl-CoA dioxygenase domain containing 1. (265 aa)
	LOC101486721	Uncharacterized protein. (107 aa)
	echs1	Enoyl CoA hydratase, short chain, 1, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa)
	acss1	Acetyl-coenzyme A synthetase. (682 aa)
	smim24	Uncharacterized protein. (133 aa)
	LOC101473024	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a. (781 aa)
	hadhb	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (473 aa)
	hmgcll1	3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1. (338 aa)
	acad8	Acyl-CoA dehydrogenase family, member 8. (418 aa)
	ECHDC1	Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (311 aa)
	hmgcl	3-hydroxy-3-methylglutaryl-CoA lyase. (337 aa)
	pex1	Peroxisomal biogenesis factor 1. (1247 aa)
	oxct1	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (524 aa)
	ivd	Isovaleryl-CoA dehydrogenase. (493 aa)
	LOC101482753	Si:dkey-33c12.12. (444 aa)
	ehhadh	Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (719 aa)
	etfb	Electron transfer flavoprotein subunit beta. (254 aa)
	acot8	Acyl-CoA thioesterase 8. (343 aa)
	LOC101486390	Zgc:85777. (435 aa)
	hsd17b4	Hydroxysteroid (17-beta) dehydrogenase 4. (737 aa)
	acox3	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (692 aa)
	acaa2	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	LOC101480450	Aldehyde dehydrogenase 9 family, member A1b; Belongs to the aldehyde dehydrogenase family. (518 aa)
	scp2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (562 aa)
	LOC101479842	Glutaryl-CoA dehydrogenase a. (440 aa)
	ENSMZEP00005013511	Si:ch211-276a17.5. (133 aa)
	LOC101466873	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (329 aa)
	htra1	HtrA serine peptidase 1b. (476 aa)
	cpt2	Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (670 aa)
	LOC101474585	Sterol carrier protein 2b. (139 aa)
	LOC101474898	AU RNA binding protein/enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (299 aa)
	LOC101483143	Aldedh domain-containing protein. (525 aa)
	LOC101474899	Zgc:174917. (268 aa)
	acads	Acyl-CoA dehydrogenase short chain. (405 aa)
	CDYL2	Chromodomain Y like 2. (511 aa)
	pccb	Propionyl-CoA carboxylase subunit beta. (560 aa)
	mccc2	Methylcrotonoyl-CoA carboxylase 2 (beta). (564 aa)
	aacs	Acetoacetyl-CoA synthetase. (676 aa)
	acaa1	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (429 aa)
	pex7	Peroxisomal biogenesis factor 7. (330 aa)
	LOC101485952	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (329 aa)
	ephx2	Epoxide hydrolase 2, cytoplasmic. (561 aa)
	LOC101487783	Zgc:113142; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (343 aa)
	hibch	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (382 aa)
	acadl	Acyl-CoA dehydrogenase long chain. (442 aa)
	LOC101468911	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
	mccc1	Methylcrotonoyl-CoA carboxylase 1 (alpha). (715 aa)
	LOC101470177	Uncharacterized protein. (126 aa)
	acacb	Acetyl-CoA carboxylase beta. (2406 aa)
	mlycd	Malonyl-CoA decarboxylase. (504 aa)
	LOC101486165	Acetyl-coenzyme A synthetase. (689 aa)
	rpp14	Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (129 aa)
	LOC101475816	Zgc:101569; Belongs to the enoyl-CoA hydratase/isomerase family. (313 aa)
	LOC101486747	Malate synthase-like. (550 aa)
	LOC101480072	3-hydroxybutyrate dehydrogenase, type 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (361 aa)
	pex5	Peroxisomal biogenesis factor 5. (642 aa)
	acat2	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
	pcca	Propionyl-CoA carboxylase subunit alpha. (719 aa)
	ENSMZEP00005024872	Uncharacterized protein. (422 aa)
	pex12	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (350 aa)
	fam185a	Family with sequence similarity 185 member A. (387 aa)
	echdc2	Enoyl CoA hydratase domain containing 2; Belongs to the enoyl-CoA hydratase/isomerase family. (332 aa)
	cdyl	Chromodomain protein, Y-like. (558 aa)
	hadh	Uncharacterized protein. (309 aa)
	decr1	2,4-dienoyl CoA reductase 1, mitochondrial. (370 aa)
	agxt2	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (516 aa)
	eci2	Enoyl-CoA delta isomerase 2. (397 aa)
	aldh6a1	Aldehyde dehydrogenase 6 family member A1. (526 aa)
	acadvl	Acyl-CoA dehydrogenase very long chain. (659 aa)
	pex2	Peroxisomal biogenesis factor 2. (330 aa)
	acad11	Acyl-CoA dehydrogenase family, member 11. (774 aa)
	pex10	Peroxisomal biogenesis factor 10. (322 aa)
	ENSMZEP00005030008	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (306 aa)
	etfa	Electron transfer flavoprotein subunit alpha. (333 aa)
	ENSMZEP00005030377	Peroxisomal biogenesis factor 5-like b. (331 aa)
	LOC101465382	Uncharacterized protein. (102 aa)
	hsdl2	Hydroxysteroid dehydrogenase like 2. (419 aa)
	acat1	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (420 aa)
	bdh2	3-hydroxybutyrate dehydrogenase, type 2. (245 aa)
	aldh16a1	Aldehyde dehydrogenase 16 family, member A1. (798 aa)
	acadm	Acyl-CoA dehydrogenase medium chain. (424 aa)
	LOC101484602	Acyl-CoA synthetase short chain family member 2 like. (684 aa)
	LOC101464128	Uncharacterized protein. (330 aa)
	LOC101464407	Enoyl CoA hydratase 1, peroxisomal. (306 aa)
	LOC101471569	Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (352 aa)
	LOC112432656	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (279 aa)
	LOC112432925	Lon peptidase 2, peroxisomal. (294 aa)
	acss2	Acetyl-coenzyme A synthetase. (679 aa)
	LOC101484981	HtrA serine peptidase 1a. (478 aa)
	UBE2D1	Ubiquitin-conjugating enzyme E2D 1a; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	tysnd1	Trypsin domain containing 1. (529 aa)
	LOC101479840	Si:ch211-198n5.11. (576 aa)
	ENSMZEP00005038062	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (311 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDYL2	ECHDC1	ENSMZEP00005016352	ENSMZEP00005007435	Chromodomain Y like 2.	Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.556
CDYL2	ENSMZEP00005002963	ENSMZEP00005016352	ENSMZEP00005002963	Chromodomain Y like 2.	Uncharacterized protein.	0.588
CDYL2	ENSMZEP00005013511	ENSMZEP00005016352	ENSMZEP00005013511	Chromodomain Y like 2.	Si:ch211-276a17.5.	0.588
CDYL2	ENSMZEP00005024872	ENSMZEP00005016352	ENSMZEP00005024872	Chromodomain Y like 2.	Uncharacterized protein.	0.548
CDYL2	ENSMZEP00005030377	ENSMZEP00005016352	ENSMZEP00005030377	Chromodomain Y like 2.	Peroxisomal biogenesis factor 5-like b.	0.598
CDYL2	GCDH	ENSMZEP00005016352	ENSMZEP00005002944	Chromodomain Y like 2.	Glutaryl-CoA dehydrogenase b.	0.588
CDYL2	LOC101464128	ENSMZEP00005016352	ENSMZEP00005032953	Chromodomain Y like 2.	Uncharacterized protein.	0.695
CDYL2	LOC101464407	ENSMZEP00005016352	ENSMZEP00005032959	Chromodomain Y like 2.	Enoyl CoA hydratase 1, peroxisomal.	0.695
CDYL2	LOC101465382	ENSMZEP00005016352	ENSMZEP00005030594	Chromodomain Y like 2.	Uncharacterized protein.	0.682
CDYL2	LOC101466873	ENSMZEP00005016352	ENSMZEP00005013675	Chromodomain Y like 2.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.428
CDYL2	LOC101468911	ENSMZEP00005016352	ENSMZEP00005020115	Chromodomain Y like 2.	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family.	0.428
CDYL2	LOC101470177	ENSMZEP00005016352	ENSMZEP00005021207	Chromodomain Y like 2.	Uncharacterized protein.	0.682
CDYL2	LOC101471569	ENSMZEP00005016352	ENSMZEP00005033232	Chromodomain Y like 2.	Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.537
CDYL2	LOC101473024	ENSMZEP00005016352	ENSMZEP00005006133	Chromodomain Y like 2.	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a.	0.428
CDYL2	LOC101474585	ENSMZEP00005016352	ENSMZEP00005014582	Chromodomain Y like 2.	Sterol carrier protein 2b.	0.879
CDYL2	LOC101474898	ENSMZEP00005016352	ENSMZEP00005014626	Chromodomain Y like 2.	AU RNA binding protein/enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.502
CDYL2	LOC101475816	ENSMZEP00005016352	ENSMZEP00005023094	Chromodomain Y like 2.	Zgc:101569; Belongs to the enoyl-CoA hydratase/isomerase family.	0.467
CDYL2	LOC101479840	ENSMZEP00005016352	ENSMZEP00005037582	Chromodomain Y like 2.	Si:ch211-198n5.11.	0.519
CDYL2	LOC101479842	ENSMZEP00005016352	ENSMZEP00005013495	Chromodomain Y like 2.	Glutaryl-CoA dehydrogenase a.	0.588
CDYL2	LOC101480240	ENSMZEP00005016352	ENSMZEP00005000194	Chromodomain Y like 2.	Uncharacterized protein.	0.682