78 items (Maylandia zebra) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	prdm14	PR domain containing 14. (601 aa)
	LOC101463634	Paired box 2a. (391 aa)
	ENSMZEP00005036941	Uncharacterized protein. (406 aa)
	dhh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (513 aa)
	LOC101470732	Homeobox C10a. (330 aa)
	ENSMZEP00005036136	Uncharacterized protein. (356 aa)
	SOX18	SRY-box transcription factor 18. (563 aa)
	LOC101480282	Eomesodermin homolog a. (646 aa)
	mib1	Mindbomb E3 ubiquitin protein ligase 1. (1009 aa)
	LOC101482292	Forkhead box A3. (466 aa)
	LOC101485133	SSD domain-containing protein. (1337 aa)
	Apc	APC_N_CC domain-containing protein. (220 aa)
	LOC101466461	HMG box domain-containing protein. (580 aa)
	LOC112429674	Dispatched homolog 1 (Drosophila). (1571 aa)
	LOC101486127	ISL LIM homeobox 2a. (334 aa)
	nkx2-2	NK2 homeobox 2b. (260 aa)
	LOC101471866	Peptidylprolyl isomerase. (467 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (415 aa)
	en2	Homeobox protein engrailed-like. (268 aa)
	pax5	Paired box 5. (425 aa)
	LOC101475168	ISL LIM homeobox 1. (349 aa)
	foxh1	Forkhead box H1. (514 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (229 aa)
	gsx2	GS homeobox 2. (238 aa)
	rax	Retinal homeobox gene 3. (315 aa)
	LHX3	LIM homeobox 3. (397 aa)
	tbx15	T-box transcription factor 15. (608 aa)
	pax8	Paired box 8. (426 aa)
	LOC101474152	T-box transcription factor 5a. (525 aa)
	tbx3	T-box transcription factor 3a. (710 aa)
	lhx9	LIM homeobox 9. (410 aa)
	sox17	SRY-box transcription factor 17. (397 aa)
	LOC101471115	Uncharacterized protein. (333 aa)
	lhx2	LIM homeobox 2b. (417 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (238 aa)
	LOC101473163	T-box transcription factor Ta. (425 aa)
	tbx5	Uncharacterized protein. (529 aa)
	scube2	Signal peptide, CUB domain, EGF-like 2. (1020 aa)
	LOC101470264	Uncharacterized protein. (315 aa)
	tbx20	T-box transcription factor 20. (437 aa)
	LOC101487360	T-box transcription factor 6. (803 aa)
	ENSMZEP00005016260	Uncharacterized protein. (382 aa)
	tcf7l1	Transcription factor 7 like 1b. (581 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	LOC101486361	BHLH domain-containing protein. (2191 aa)
	LOC101479578	T-box transcription factor 18. (511 aa)
	LOC101472658	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (437 aa)
	dlx3	Distal-less homeobox 3b. (281 aa)
	ISL2	ISL LIM homeobox 2b. (359 aa)
	LOC101464751	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
	LOC101466389	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (394 aa)
	tbxt	T-box transcription factor Tb. (436 aa)
	LOC101483795	T-box transcription factor 2a. (645 aa)
	tbx21	T-box transcription factor 21. (621 aa)
	LOC105941156	Uncharacterized protein. (336 aa)
	tbr1	T-box brain transcription factor 1b. (662 aa)
	zc4h2	Zinc finger, C4H2 domain containing. (225 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (825 aa)
	LOC101466010	T-box transcription factor 16. (465 aa)
	TBX22	T-box transcription factor 22. (506 aa)
	ptch1	Patched 1. (1551 aa)
	fkbp8	Peptidylprolyl isomerase. (401 aa)
	LOC101476499	Eomesodermin homolog b. (603 aa)
	ENSMZEP00005007667	Uncharacterized protein. (321 aa)
	LOC101466937	NK2 homeobox 2a. (273 aa)
	vsx1	Visual system homeobox 1 homolog, chx10-like. (360 aa)
	lhx4	LIM homeobox 4. (383 aa)
	hey1	Hes-related family bHLH transcription factor with YRPW motif 1. (331 aa)
	ENSMZEP00005004455	Paired domain-containing protein. (148 aa)
	ENSMZEP00005004331	T-box transcription factor 3b. (380 aa)
	sufu	Suppressor of fused homolog. (484 aa)
	apc2	APC regulator of WNT signaling pathway 2. (2516 aa)
	tbx4	T-box transcription factor 4. (534 aa)
	TBX2	T-box transcription factor 2. (684 aa)
	pax2	Paired box 2b. (387 aa)
	tbx1	T-box transcription factor 1. (501 aa)
	LOC101469964	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (424 aa)
	mnx1	Motor neuron and pancreas homeobox 1. (314 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Apc	LOC101464751	ENSMZEP00005031072	ENSMZEP00005010906	APC_N_CC domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.471
Apc	LOC101466389	ENSMZEP00005031072	ENSMZEP00005010882	APC_N_CC domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.471
Apc	LOC101466461	ENSMZEP00005031072	ENSMZEP00005030777	APC_N_CC domain-containing protein.	HMG box domain-containing protein.	0.600
Apc	apc2	ENSMZEP00005031072	ENSMZEP00005003894	APC_N_CC domain-containing protein.	APC regulator of WNT signaling pathway 2.	0.900
Apc	tcf7l1	ENSMZEP00005031072	ENSMZEP00005015053	APC_N_CC domain-containing protein.	Transcription factor 7 like 1b.	0.600
ENSMZEP00005016260	LOC101476499	ENSMZEP00005016260	ENSMZEP00005008232	Uncharacterized protein.	Eomesodermin homolog b.	0.469
ENSMZEP00005016260	LOC101480282	ENSMZEP00005016260	ENSMZEP00005035422	Uncharacterized protein.	Eomesodermin homolog a.	0.518
ENSMZEP00005016260	foxh1	ENSMZEP00005016260	ENSMZEP00005028483	Uncharacterized protein.	Forkhead box H1.	0.531
ENSMZEP00005016260	tbr1	ENSMZEP00005016260	ENSMZEP00005009620	Uncharacterized protein.	T-box brain transcription factor 1b.	0.518
ISL2	LHX3	ENSMZEP00005012013	ENSMZEP00005026220	ISL LIM homeobox 2b.	LIM homeobox 3.	0.816
ISL2	lhx4	ENSMZEP00005012013	ENSMZEP00005005082	ISL LIM homeobox 2b.	LIM homeobox 4.	0.810
ISL2	mnx1	ENSMZEP00005012013	ENSMZEP00005000448	ISL LIM homeobox 2b.	Motor neuron and pancreas homeobox 1.	0.414
ISL2	tbx20	ENSMZEP00005012013	ENSMZEP00005019811	ISL LIM homeobox 2b.	T-box transcription factor 20.	0.413
ISL2	vsx1	ENSMZEP00005012013	ENSMZEP00005005219	ISL LIM homeobox 2b.	Visual system homeobox 1 homolog, chx10-like.	0.466
LHX3	ISL2	ENSMZEP00005026220	ENSMZEP00005012013	LIM homeobox 3.	ISL LIM homeobox 2b.	0.816
LHX3	LOC101475168	ENSMZEP00005026220	ENSMZEP00005028532	LIM homeobox 3.	ISL LIM homeobox 1.	0.810
LHX3	LOC101486127	ENSMZEP00005026220	ENSMZEP00005030023	LIM homeobox 3.	ISL LIM homeobox 2a.	0.810
LHX3	mnx1	ENSMZEP00005026220	ENSMZEP00005000448	LIM homeobox 3.	Motor neuron and pancreas homeobox 1.	0.448
LOC101464751	Apc	ENSMZEP00005010906	ENSMZEP00005031072	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	APC_N_CC domain-containing protein.	0.471
LOC101464751	LOC105941156	ENSMZEP00005010906	ENSMZEP00005009851	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.833