32 items (Maylandia zebra) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101474809	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1720 aa)
	asic4	Acid-sensing (proton-gated) ion channel family member 4a; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (511 aa)
	lysmd3	LysM, putative peptidoglycan-binding, domain containing 3. (319 aa)
	LOC101479049	Two pore segment channel 3. (772 aa)
	scn3b	Sodium channel, voltage-gated, type III, beta. (220 aa)
	LOC101487210	Cyclic nucleotide-binding domain-containing protein. (1497 aa)
	tpcn1	Two pore segment channel 1. (831 aa)
	LOC101480563	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2010 aa)
	pkd2	Polycystic kidney disease 2. (902 aa)
	LOC101482514	Hyperpolarization activated cyclic nucleotide-gated potassium channel 1. (932 aa)
	ENSMZEP00005027327	Uncharacterized protein. (638 aa)
	LOC101476829	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1659 aa)
	ENSMZEP00005000088	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (447 aa)
	ENSMZEP00005000127	Ion_trans domain-containing protein. (200 aa)
	LOC101469760	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1812 aa)
	LOC101483937	Sodium channel, voltage-gated, type I, beta a. (223 aa)
	ENSMZEP00005003584	Uncharacterized protein. (95 aa)
	LOC101482826	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1688 aa)
	LOC101478365	Cyclic nucleotide-binding domain-containing protein. (1181 aa)
	ENSMZEP00005006599	Sodium channel, voltage-gated, type II, beta. (210 aa)
	LOC101467808	Sodium channel, voltage-gated, type IV, beta a. (233 aa)
	LOC101485464	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1849 aa)
	LOC101464243	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1824 aa)
	LOC101466081	Hyperpolarization activated cyclic nucleotide-gated potassium channel 4. (1438 aa)
	LOC101485512	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1956 aa)
	HCN2	Hyperpolarization activated cyclic nucleotide-gated potassium channel 2b. (960 aa)
	LOC101470714	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1651 aa)
	nalcn	Sodium leak channel, non-selective. (1753 aa)
	LOC101467375	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1952 aa)
	LOC101487604	Cyclic nucleotide-binding domain-containing protein. (959 aa)
	scn1b	Ig-like domain-containing protein. (229 aa)
	ENSMZEP00005035602	Hyperpolarization activated cyclic nucleotide-gated potassium channel 3. (289 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMZEP00005000088	ENSMZEP00005006599	ENSMZEP00005000088	ENSMZEP00005006599	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel, voltage-gated, type II, beta.	0.798
ENSMZEP00005000088	ENSMZEP00005027327	ENSMZEP00005000088	ENSMZEP00005027327	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Uncharacterized protein.	0.755
ENSMZEP00005000088	LOC101464243	ENSMZEP00005000088	ENSMZEP00005008792	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.502
ENSMZEP00005000088	LOC101467375	ENSMZEP00005000088	ENSMZEP00005030485	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.496
ENSMZEP00005000088	LOC101467808	ENSMZEP00005000088	ENSMZEP00005006617	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel, voltage-gated, type IV, beta a.	0.558
ENSMZEP00005000088	LOC101469760	ENSMZEP00005000088	ENSMZEP00005000458	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.497
ENSMZEP00005000088	LOC101474809	ENSMZEP00005000088	ENSMZEP00005015266	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.501
ENSMZEP00005000088	LOC101476829	ENSMZEP00005000088	ENSMZEP00005009141	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.502
ENSMZEP00005000088	LOC101480563	ENSMZEP00005000088	ENSMZEP00005024157	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.496
ENSMZEP00005000088	LOC101483937	ENSMZEP00005000088	ENSMZEP00005002899	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel, voltage-gated, type I, beta a.	0.772
ENSMZEP00005000088	LOC101485512	ENSMZEP00005000088	ENSMZEP00005010060	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.494
ENSMZEP00005000088	scn1b	ENSMZEP00005000088	ENSMZEP00005035074	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Ig-like domain-containing protein.	0.772
ENSMZEP00005000088	scn3b	ENSMZEP00005000088	ENSMZEP00005021090	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel, voltage-gated, type III, beta.	0.649
ENSMZEP00005000127	ENSMZEP00005006599	ENSMZEP00005000127	ENSMZEP00005006599	Ion_trans domain-containing protein.	Sodium channel, voltage-gated, type II, beta.	0.698
ENSMZEP00005000127	LOC101467808	ENSMZEP00005000127	ENSMZEP00005006617	Ion_trans domain-containing protein.	Sodium channel, voltage-gated, type IV, beta a.	0.558
ENSMZEP00005000127	LOC101483937	ENSMZEP00005000127	ENSMZEP00005002899	Ion_trans domain-containing protein.	Sodium channel, voltage-gated, type I, beta a.	0.659
ENSMZEP00005000127	scn1b	ENSMZEP00005000127	ENSMZEP00005035074	Ion_trans domain-containing protein.	Ig-like domain-containing protein.	0.659
ENSMZEP00005000127	scn3b	ENSMZEP00005000127	ENSMZEP00005021090	Ion_trans domain-containing protein.	Sodium channel, voltage-gated, type III, beta.	0.474
ENSMZEP00005003584	ENSMZEP00005006599	ENSMZEP00005003584	ENSMZEP00005006599	Uncharacterized protein.	Sodium channel, voltage-gated, type II, beta.	0.698
ENSMZEP00005003584	LOC101467808	ENSMZEP00005003584	ENSMZEP00005006617	Uncharacterized protein.	Sodium channel, voltage-gated, type IV, beta a.	0.558