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| | zmpste24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa) |
| | ENSMZEP00005000936 | Uncharacterized protein. (168 aa) |
| | rnf8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (544 aa) |
| | LOC101485808 | Uncharacterized protein. (183 aa) |
| | ENSMZEP00005001914 | Reverse transcriptase domain-containing protein. (1007 aa) |
| | mfsd11 | Major facilitator superfamily domain containing 11. (454 aa) |
| | lig4 | DNA ligase. (910 aa) |
| | LOC112432380 | Uncharacterized protein. (204 aa) |
| | rhno1 | Uncharacterized protein. (295 aa) |
| | msh2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (937 aa) |
| | LOC101472093 | Protein kinase domain-containing protein. (668 aa) |
| | Rad9b | Uncharacterized protein. (124 aa) |
| | rnf168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...] (430 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (389 aa) |
| | atr | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2554 aa) |
| | kdm1a | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (834 aa) |
| | ercc6 | Excision repair cross-complementation group 6. (1439 aa) |
| | cdca7 | Cell division cycle associated 7a. (450 aa) |
| | ikbip | Uncharacterized protein. (408 aa) |
| | map3k20 | Uncharacterized protein. (804 aa) |
| | men1 | Multiple endocrine neoplasia I. (628 aa) |
| | itgb6 | Integrin beta; Belongs to the integrin beta chain family. (689 aa) |
| | Itgb6 | PSI domain-containing protein. (114 aa) |
| | ercc8 | Excision repair cross-complementation group 8. (409 aa) |
| | fbxo4 | F-box protein 4. (396 aa) |
| | tank | TRAF family member-associated NFKB activator. (335 aa) |
| | LOC105941156 | Uncharacterized protein. (336 aa) |
| | cdca7l | Cell division cycle associated 7b. (410 aa) |
| | LOC101485000 | Deoxyribonuclease 1 like 4, tandem duplicate 2. (328 aa) |
| | xrcc5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (723 aa) |
| | LOC101486342 | Uncharacterized protein. (191 aa) |
| | ENSMZEP00005012187 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (691 aa) |
| | babam2 | BRISC and BRCA1 A complex member 2. (391 aa) |
| | ercc1 | Excision repair cross-complementation group 1. (352 aa) |
| | LOC101476906 | BRCA1 associated RING domain 1. (713 aa) |
| | GADD45A | Growth arrest and DNA-damage-inducible, alpha, b. (183 aa) |
| | fancd2 | FA complementation group D2. (1425 aa) |
| | ENSMZEP00005014399 | Uncharacterized protein. (165 aa) |
| | dcun1d3 | DCN1-like protein. (326 aa) |
| | sfrp2 | Secreted frizzled-related protein 2. (295 aa) |
| | sirt1 | Deacetylase sirtuin-type domain-containing protein. (715 aa) |
| | brca2 | BRCA2 DNA repair associated. (3307 aa) |
| | ENSMZEP00005015265 | Ints3 and nabp interacting protein. (89 aa) |
| | ect2 | Epithelial cell transforming 2. (939 aa) |
| | ticrr | Treslin_N domain-containing protein. (1869 aa) |
| | LOC101481251 | X-ray repair complementing defective repair in Chinese hamster cells 4. (335 aa) |
| | brat1 | BRCA1-associated ATM activator 1. (912 aa) |
| | ints3 | Integrator complex subunit 3. (1019 aa) |
| | ENSMZEP00005016530 | TAN domain-containing protein. (177 aa) |
| | Atm | Uncharacterized protein. (139 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (336 aa) |
| | ENSMZEP00005017141 | Reverse transcriptase domain-containing protein. (781 aa) |
| | ino80 | INO80 complex ATPase subunit. (1506 aa) |
| | ENSMZEP00005018137 | Reverse transcriptase domain-containing protein. (758 aa) |
| | Brcc3 | BRCA1/BRCA2-containing complex, subunit 3. (278 aa) |
| | kars1 | Lysine--tRNA ligase. (605 aa) |
| | xrcc4 | Uncharacterized protein. (294 aa) |
| | cop1 | COP1 E3 ubiquitin ligase. (715 aa) |
| | ENSMZEP00005020665 | Reverse transcriptase domain-containing protein. (792 aa) |
| | rfwd3 | Ring finger and WD repeat domain 3. (707 aa) |
| | tp53bp1 | Tumor protein p53 binding protein, 1. (1709 aa) |
| | LOC101477392 | Nucleic acid binding protein 1a. (220 aa) |
| | LOC101476025 | Deoxyribonuclease; Belongs to the DNase I family. (280 aa) |
| | INIP | INTS3 and NABP interacting protein. (73 aa) |
| | LOC101484052 | Zgc:153993. (274 aa) |
| | swi5 | SWI5 homologous recombination repair protein. (135 aa) |
| | LOC112430600 | Reverse transcriptase domain-containing protein. (1080 aa) |
| | topbp1 | DNA topoisomerase II binding protein 1. (1514 aa) |
| | LOC101483818 | Crystallin, alpha B, a; Belongs to the small heat shock protein (HSP20) family. (164 aa) |
| | ptprc | Protein tyrosine phosphatase receptor type C. (1195 aa) |
| | babam1 | BRISC and BRCA1 A complex member 1. (378 aa) |
| | smpd1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (602 aa) |
| | rad1 | RAD1 homolog (S. pombe). (279 aa) |
| | LOC101477921 | BH4_2 domain-containing protein. (198 aa) |
| | XRCC2 | X-ray repair cross complementing 2. (301 aa) |
| | chek2 | Checkpoint kinase 2. (490 aa) |
| | brca1 | Uncharacterized protein. (1389 aa) |
| | blm | BLM RecQ like helicase. (1381 aa) |
| | LOC101485820 | Uncharacterized protein. (446 aa) |
| | bax | Uncharacterized protein. (205 aa) |
| | ENSMZEP00005031749 | Uncharacterized protein. (263 aa) |
| | LOC101482089 | ETS transcription factor ELK1. (582 aa) |
| | LOC101473892 | Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa) |
| | uimc1 | RAP80_UIM domain-containing protein. (957 aa) |
| | spidr | Uncharacterized protein. (935 aa) |
| | bcl2 | BCL2 apoptosis regulator b. (228 aa) |
| | stk11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (424 aa) |
| | LOC101481520 | DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1465 aa) |
| | abcg5 | ATP-binding cassette, sub-family G (WHITE), member 5. (656 aa) |
| | xrcc6 | X-ray repair complementing defective repair in Chinese hamster cells 6. (610 aa) |
| | eya3 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (607 aa) |
