STRINGSTRING
nfe2l2 nfe2l2 plcg2 plcg2 LOC101473889 LOC101473889 bmpr2 bmpr2 LOC101463670 LOC101463670 LOC101470992 LOC101470992 bcas3 bcas3 LOC101476800 LOC101476800 ENSMZEP00005003192 ENSMZEP00005003192 LOC101481167 LOC101481167 fgf1 fgf1 fgf2 fgf2 mtor mtor LOC101466107 LOC101466107 LOC101475825 LOC101475825 vegfc vegfc LOC101470035 LOC101470035 ENSMZEP00005007856 ENSMZEP00005007856 gpi gpi itgb1bp1 itgb1bp1 LOC101487929 LOC101487929 LOC101477305 LOC101477305 LOC101474055 LOC101474055 sp1 sp1 LOC101477172 LOC101477172 LOC101475228 LOC101475228 CTSH CTSH LOC101465520 LOC101465520 GATA2 GATA2 capn7 capn7 bsg bsg mst1r mst1r lgmn lgmn LOC101487525 LOC101487525 sirt1 sirt1 fgf16 fgf16 LOC101468745 LOC101468745 ARF6 ARF6 fgf7 fgf7 RIN2 RIN2 LOC101487698 LOC101487698 met met LOC101477206 LOC101477206 vegfa vegfa pik3cg pik3cg glipr2 glipr2 LOC101469724 LOC101469724 LOC112430746 LOC112430746 tsta3 tsta3 nrp1 nrp1 LOC101473405 LOC101473405 igf2 igf2 sash1 sash1 LOC101465260 LOC101465260 LOC101477720 LOC101477720 LOC101464631 LOC101464631 LOC101463742 LOC101463742 ENSMZEP00005026114 ENSMZEP00005026114 plpp3 plpp3 rreb1 rreb1 LOC101478446 LOC101478446 LOC101479225 LOC101479225 ENSMZEP00005027596 ENSMZEP00005027596 aamp aamp LOC101471620 LOC101471620 LOC101487191 LOC101487191 ENSMZEP00005031405 ENSMZEP00005031405 hspb1 hspb1 LOC101477480 LOC101477480 LOC101473892 LOC101473892 tgfb2 tgfb2 LOC101465777 LOC101465777 ENSMZEP00005033929 ENSMZEP00005033929 LOC101474749 LOC101474749 TGFBR2 TGFBR2 plcg1 plcg1 agt agt
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nfe2l2Nuclear factor, erythroid 2-like 2a. (581 aa)
plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1249 aa)
LOC101473889Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1067 aa)
LOC101463670JunE proto-oncogene, AP-1 transcription factor subunit. (343 aa)
LOC101470992Ras and Rab interactor 1a. (512 aa)
bcas3BCAS3 microtubule associated cell migration factor. (932 aa)
LOC101476800ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (552 aa)
ENSMZEP00005003192Fibroblast growth factor binding protein 1b. (221 aa)
LOC101481167Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (182 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2516 aa)
LOC101466107Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
LOC101475825RAB25, member RAS oncogene family a. (210 aa)
vegfcVascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family. (396 aa)
LOC101470035ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (518 aa)
ENSMZEP00005007856Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (477 aa)
gpiGlucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
itgb1bp1Integrin beta 1 binding protein 1. (202 aa)
LOC101487929Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (552 aa)
LOC101477305Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (515 aa)
LOC101474055ADAM metallopeptidase domain 17a. (861 aa)
sp1Sp1 transcription factor. (707 aa)
LOC101477172Zinc finger CCCH-type containing 12A. (632 aa)
LOC101475228ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (551 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (309 aa)
LOC101465520acidPPc domain-containing protein. (338 aa)
GATA2GATA binding protein 2. (455 aa)
capn7Calpain 7; Belongs to the peptidase C2 family. (824 aa)
bsgBasigin. (390 aa)
mst1rMacrophage stimulating 1 receptor b. (1373 aa)
lgmnLegumain. (434 aa)
LOC101487525GATA binding protein 2a. (458 aa)
sirt1Deacetylase sirtuin-type domain-containing protein. (715 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC101468745Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (182 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
RIN2Ras and Rab interactor 2. (981 aa)
LOC101487698SAM and SH3 domain containing 1b. (1092 aa)
metMET proto-oncogene, receptor tyrosine kinase. (1420 aa)
LOC101477206ADAM metallopeptidase domain 17b. (827 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
pik3cgPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1122 aa)
glipr2GLI pathogenesis-related 2, like; Belongs to the CRISP family. (156 aa)
LOC101469724Macrophage stimulating 1 receptor a. (1364 aa)
LOC112430746Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (486 aa)
tsta3Tissue specific transplantation antigen P35B. (318 aa)
nrp1Neuropilin; Belongs to the neuropilin family. (915 aa)
LOC1014734051-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1312 aa)
igf2Insulin-like growth factor 2b. (215 aa)
sash1SAM and SH3 domain containing 1a. (1351 aa)
LOC101465260RAB25, member RAS oncogene family b. (207 aa)
LOC101477720ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (517 aa)
LOC101464631Heat shock protein, alpha-crystallin-related, b15; Belongs to the small heat shock protein (HSP20) family. (209 aa)
LOC101463742Ras and Rab interactor 2. (1099 aa)
ENSMZEP00005026114Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (261 aa)
plpp3Phospholipid phosphatase 3. (333 aa)
rreb1Ras responsive element binding protein 1a. (1885 aa)
LOC101478446Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (613 aa)
LOC101479225Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
ENSMZEP00005027596Uncharacterized protein. (112 aa)
aampAngio-associated, migratory cell protein. (418 aa)
LOC101471620Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family. (1095 aa)
LOC101487191CD40 molecule, TNF receptor superfamily member 5. (308 aa)
ENSMZEP00005031405Zinc finger CCCH-type containing 12A. (296 aa)
hspb1Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family. (203 aa)
LOC101477480Uncharacterized protein. (1235 aa)
LOC101473892Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
LOC101465777Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (596 aa)
ENSMZEP00005033929Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (627 aa)
LOC101474749C3H1-type domain-containing protein. (644 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (538 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1321 aa)
agtAngiotensinogen; Belongs to the serpin family. (463 aa)
Your Current Organism:
Maylandia zebra
NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna
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