STRINGSTRING
terf2ip terf2ip ENSMZEP00005034571 ENSMZEP00005034571 RPA1 RPA1 LOC101464528 LOC101464528 pinx1 pinx1 dkc1 dkc1 ENSMZEP00005019048 ENSMZEP00005019048 ENSMZEP00005019039 ENSMZEP00005019039 nop10 nop10 LOC101478306 LOC101478306 pot1 pot1 LOC101471106 LOC101471106 gar1 gar1 rad50 rad50 ENSMZEP00005005357 ENSMZEP00005005357 LOC106675102 LOC106675102 nhp2 nhp2 telo2 telo2 wrap53 wrap53 ptges3 ptges3 rpa1 rpa1 tert tert rad51 rad51 stn1 stn1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
terf2ipUncharacterized protein. (617 aa)
ENSMZEP00005034571Uncharacterized protein. (934 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (640 aa)
LOC101464528Zinc finger and BTB domain containing 48. (734 aa)
pinx1PIN2 (TERF1) interacting telomerase inhibitor 1. (374 aa)
dkc1Dyskeratosis congenita 1, dyskerin. (500 aa)
ENSMZEP00005019048Uncharacterized protein. (255 aa)
ENSMZEP00005019039AAA_23 domain-containing protein. (53 aa)
nop10NOP10 ribonucleoprotein homolog (yeast). (64 aa)
LOC101478306Uncharacterized protein. (496 aa)
pot1Protection of telomeres 1 homolog. (669 aa)
LOC101471106Prostaglandin E synthase 3a (cytosolic). (159 aa)
gar1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (223 aa)
rad50RAD50 homolog, double strand break repair protein. (1312 aa)
ENSMZEP00005005357Uncharacterized protein. (1056 aa)
LOC106675102Uncharacterized protein. (1000 aa)
nhp2Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (154 aa)
telo2TEL2, telomere maintenance 2, homolog (S. cerevisiae). (803 aa)
wrap53WD repeat containing, antisense to TP53. (544 aa)
ptges3Prostaglandin E synthase 3b (cytosolic). (159 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
tertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1095 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (336 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (365 aa)
Your Current Organism:
Maylandia zebra
NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna
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