(21 nodes) RNA polymerase II general transcription initiation factor activity network (Maylandia zebra)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gtf2b	General transcription factor IIB. (318 aa)
	gtf2a1	General transcription factor IIA, 1. (385 aa)
	taf7l	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (362 aa)
	taf10	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (186 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
	gtf2f1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (532 aa)
	tbp	TATA box binding protein. (307 aa)
	ENSMZEP00005014012	Uncharacterized protein. (172 aa)
	dr1	Down-regulator of transcription 1. (176 aa)
	snapc2	Uncharacterized protein. (481 aa)
	gtf2e2	General transcription factor IIE, polypeptide 2, beta. (336 aa)
	snapc5	Small nuclear RNA activating complex, polypeptide 5. (119 aa)
	taf6l	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (650 aa)
	gtf2a2	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (111 aa)
	gtf2e1	General transcription factor IIE, polypeptide 1, alpha. (439 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (300 aa)
	LOC101472252	CBFD_NFYB_HMF domain-containing protein. (149 aa)
	taf6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (638 aa)
	drap1	DR1-associated protein 1 (negative cofactor 2 alpha). (235 aa)
	taf1	Transcription initiation factor TFIID subunit. (1853 aa)
	snapc4	Uncharacterized protein. (1238 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMZEP00005014012	LOC101472252	ENSMZEP00005014012	ENSMZEP00005003252	Uncharacterized protein.	CBFD_NFYB_HMF domain-containing protein.	0.766
ENSMZEP00005014012	dr1	ENSMZEP00005014012	ENSMZEP00005013394	Uncharacterized protein.	Down-regulator of transcription 1.	0.898
ENSMZEP00005014012	drap1	ENSMZEP00005014012	ENSMZEP00005011336	Uncharacterized protein.	DR1-associated protein 1 (negative cofactor 2 alpha).	0.903
ENSMZEP00005014012	gtf2a1	ENSMZEP00005014012	ENSMZEP00005008243	Uncharacterized protein.	General transcription factor IIA, 1.	0.920
ENSMZEP00005014012	gtf2a2	ENSMZEP00005014012	ENSMZEP00005004377	Uncharacterized protein.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.960
ENSMZEP00005014012	gtf2b	ENSMZEP00005014012	ENSMZEP00005006270	Uncharacterized protein.	General transcription factor IIB.	0.966
ENSMZEP00005014012	gtf2e1	ENSMZEP00005014012	ENSMZEP00005003340	Uncharacterized protein.	General transcription factor IIE, polypeptide 1, alpha.	0.967
ENSMZEP00005014012	gtf2e2	ENSMZEP00005014012	ENSMZEP00005031843	Uncharacterized protein.	General transcription factor IIE, polypeptide 2, beta.	0.930
ENSMZEP00005014012	gtf2f1	ENSMZEP00005014012	ENSMZEP00005016623	Uncharacterized protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.936
ENSMZEP00005014012	gtf2h3	ENSMZEP00005014012	ENSMZEP00005001796	Uncharacterized protein.	General transcription factor IIH, polypeptide 3.	0.951
ENSMZEP00005014012	gtf2h4	ENSMZEP00005014012	ENSMZEP00005023581	Uncharacterized protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.947
ENSMZEP00005014012	snapc2	ENSMZEP00005014012	ENSMZEP00005012636	Uncharacterized protein.	Uncharacterized protein.	0.553
ENSMZEP00005014012	snapc4	ENSMZEP00005014012	ENSMZEP00005004729	Uncharacterized protein.	Uncharacterized protein.	0.839
ENSMZEP00005014012	snapc5	ENSMZEP00005014012	ENSMZEP00005030428	Uncharacterized protein.	Small nuclear RNA activating complex, polypeptide 5.	0.702
ENSMZEP00005014012	taf1	ENSMZEP00005014012	ENSMZEP00005021294	Uncharacterized protein.	Transcription initiation factor TFIID subunit.	0.964
ENSMZEP00005014012	taf10	ENSMZEP00005014012	ENSMZEP00005027427	Uncharacterized protein.	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	0.964
ENSMZEP00005014012	taf6	ENSMZEP00005014012	ENSMZEP00005021834	Uncharacterized protein.	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.965
ENSMZEP00005014012	taf6l	ENSMZEP00005014012	ENSMZEP00005029949	Uncharacterized protein.	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor.	0.885
ENSMZEP00005014012	taf7l	ENSMZEP00005014012	ENSMZEP00005009024	Uncharacterized protein.	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.964
LOC101472252	ENSMZEP00005014012	ENSMZEP00005003252	ENSMZEP00005014012	CBFD_NFYB_HMF domain-containing protein.	Uncharacterized protein.	0.766