(20 nodes) Granulocyte differentiation network (Maylandia zebra)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101483328	Nuclear receptor coactivator. (1464 aa)
	LOC106675778	Uncharacterized protein. (226 aa)
	LOC101472595	Uncharacterized protein. (189 aa)
	cebpa	CCAAT/enhancer-binding protein. (291 aa)
	LOC101468524	Sp3b transcription factor. (677 aa)
	SP3	Sp3a transcription factor. (671 aa)
	LOC112434729	Dehydrogenase/reductase (SDR family) member 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (297 aa)
	usb1	U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (280 aa)
	LOC101485806	GATA binding protein 1a. (424 aa)
	LOC105941359	BZIP domain-containing protein. (201 aa)
	jagn1	Jagunal homolog 1b. (183 aa)
	LOC112435287	Si:dkey-61p9.11. (2101 aa)
	LOC106676777	Carrier domain-containing protein. (2101 aa)
	LOC101481829	Carrier domain-containing protein. (2079 aa)
	lef1	Lymphoid enhancer-binding factor 1. (361 aa)
	ncoa2	Nuclear receptor coactivator. (1461 aa)
	LOC101475249	Jagunal homolog 1a. (167 aa)
	Gata1	Uncharacterized protein. (246 aa)
	fasn	Coiled-coil domain containing 57. (2510 aa)
	srp54	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Gata1	LOC101468524	ENSMZEP00005032295	ENSMZEP00005001432	Uncharacterized protein.	Sp3b transcription factor.	0.401
Gata1	SP3	ENSMZEP00005032295	ENSMZEP00005006516	Uncharacterized protein.	Sp3a transcription factor.	0.469
LOC101468524	Gata1	ENSMZEP00005001432	ENSMZEP00005032295	Sp3b transcription factor.	Uncharacterized protein.	0.401
LOC101468524	LOC101485806	ENSMZEP00005001432	ENSMZEP00005013569	Sp3b transcription factor.	GATA binding protein 1a.	0.401
LOC101472595	LOC106675778	ENSMZEP00005004060	ENSMZEP00005004193	Uncharacterized protein.	Uncharacterized protein.	0.901
LOC101485806	LOC101468524	ENSMZEP00005013569	ENSMZEP00005001432	GATA binding protein 1a.	Sp3b transcription factor.	0.401
LOC101485806	SP3	ENSMZEP00005013569	ENSMZEP00005006516	GATA binding protein 1a.	Sp3a transcription factor.	0.469
LOC106675778	LOC101472595	ENSMZEP00005004193	ENSMZEP00005004060	Uncharacterized protein.	Uncharacterized protein.	0.901
SP3	Gata1	ENSMZEP00005006516	ENSMZEP00005032295	Sp3a transcription factor.	Uncharacterized protein.	0.469
SP3	LOC101485806	ENSMZEP00005006516	ENSMZEP00005013569	Sp3a transcription factor.	GATA binding protein 1a.	0.469