(14 nodes) Regulation of vascular endothelial growth factor receptor signaling pathway network (Maylandia zebra)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	hif1an	Hypoxia inducible factor 1 subunit alpha inhibitor. (354 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (415 aa)
	ENSMZEP00005030510	EMI domain-containing protein. (178 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (533 aa)
	LOC101468240	Elastin microfibril interfacer 1b. (1086 aa)
	mmrn2	Multimerin 2a. (1027 aa)
	LOC101481167	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	LOC101478630	Elastin microfibril interfacer 1a. (1018 aa)
	LOC101473889	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
	tmem204	Transmembrane protein 204. (226 aa)
	vegfc	Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family. (396 aa)
	LOC101466364	Hepatocyte growth factor-regulated tyrosine kinase substrate. (727 aa)
	nrp1	Neuropilin; Belongs to the neuropilin family. (915 aa)
	hgs	Hepatocyte growth factor-regulated tyrosine kinase substrate. (777 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101473889	nrp1	ENSMZEP00005000564	ENSMZEP00005022980	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	Neuropilin; Belongs to the neuropilin family.	0.400
LOC101481167	nrp1	ENSMZEP00005003647	ENSMZEP00005022980	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Neuropilin; Belongs to the neuropilin family.	0.400
nrp1	LOC101473889	ENSMZEP00005022980	ENSMZEP00005000564	Neuropilin; Belongs to the neuropilin family.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.400
nrp1	LOC101481167	ENSMZEP00005022980	ENSMZEP00005003647	Neuropilin; Belongs to the neuropilin family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.400
nrp1	vegfc	ENSMZEP00005022980	ENSMZEP00005007665	Neuropilin; Belongs to the neuropilin family.	Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.	0.605
vegfc	nrp1	ENSMZEP00005007665	ENSMZEP00005022980	Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.	Neuropilin; Belongs to the neuropilin family.	0.605