48 items (Maylandia zebra) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dnm3	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (828 aa)
	dnm1	Dynamin 1a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (851 aa)
	htr2b	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (467 aa)
	LOC101482025	Calcium channel, voltage-dependent, gamma subunit 8b. (416 aa)
	LOC101481740	Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (313 aa)
	CD9	Tetraspanin. (224 aa)
	ENSMZEP00005019519	Uncharacterized protein. (120 aa)
	LOC101467412	Uncharacterized protein. (149 aa)
	dnm2	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (871 aa)
	LOC101475502	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1653 aa)
	LOC101466364	Hepatocyte growth factor-regulated tyrosine kinase substrate. (727 aa)
	RAMP3	Receptor activity modifying protein 3. (165 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	ENSMZEP00005014006	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (165 aa)
	LOC101471166	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1658 aa)
	LOC101472092	Uncharacterized protein. (201 aa)
	LOC101470339	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (463 aa)
	LOC101484724	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (852 aa)
	scyl2	SCY1 like pseudokinase 2. (919 aa)
	LOC101483772	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (322 aa)
	lmbrd1	LMBR1 domain containing 1. (538 aa)
	LOC101484383	Arrestin 3. (359 aa)
	LOC101481197	Low density lipoprotein receptor adaptor protein 1a. (311 aa)
	LOC101482861	Arrestin, beta 1. (417 aa)
	LOC101467429	Receptor activity modifying protein 1. (149 aa)
	LOC101466614	Arrestin 3a, retinal (X-arrestin). (355 aa)
	cacng5	Calcium channel, voltage-dependent, gamma subunit 5a. (277 aa)
	cacng4	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (334 aa)
	LOC101467714	Atypical chemokine receptor 3a; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	ENSMZEP00005003053	Calcium channel, voltage-dependent, gamma subunit 8a. (294 aa)
	LOC101474381	Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (287 aa)
	LOC101486393	S-antigen visual arrestin. (356 aa)
	LOC101476562	Calcyon neuron-specific vesicular protein. (201 aa)
	LOC101486527	Calcium channel, voltage-dependent, gamma subunit 5b. (276 aa)
	ldlrap1	Low density lipoprotein receptor adaptor protein 1b. (312 aa)
	cacng3	Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
	fcer1g	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide. (93 aa)
	LOC101463593	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (834 aa)
	cntn2	Contactin 2. (1042 aa)
	arrb2	Arrestin, beta 2a. (414 aa)
	ENSMZEP00005032418	Uncharacterized protein. (76 aa)
	lrrtm1	Leucine rich repeat transmembrane neuronal 1. (517 aa)
	cltc	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1686 aa)
	ramp2	Receptor (G protein-coupled) activity modifying protein 2. (239 aa)
	hgs	Hepatocyte growth factor-regulated tyrosine kinase substrate. (777 aa)
	LOC101481835	Tetraspanin. (229 aa)
	DNM1	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (779 aa)
	LOC101471160	S-antigen; retina and pineal gland (arrestin) a. (369 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNM1	ENSMZEP00005014006	ENSMZEP00005027989	ENSMZEP00005014006	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.575
DNM1	LOC101471166	ENSMZEP00005027989	ENSMZEP00005013509	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.643
DNM1	LOC101475502	ENSMZEP00005027989	ENSMZEP00005017282	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.643
DNM1	cav3	ENSMZEP00005027989	ENSMZEP00005014017	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.528
DNM1	cltc	ENSMZEP00005027989	ENSMZEP00005031278	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.643
ENSMZEP00005014006	DNM1	ENSMZEP00005014006	ENSMZEP00005027989	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.575
ENSMZEP00005014006	LOC101463593	ENSMZEP00005014006	ENSMZEP00005012001	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.575
ENSMZEP00005014006	LOC101484724	ENSMZEP00005014006	ENSMZEP00005005580	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.575
ENSMZEP00005014006	cav3	ENSMZEP00005014006	ENSMZEP00005014017	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.614
ENSMZEP00005014006	dnm1	ENSMZEP00005014006	ENSMZEP00005025860	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dynamin 1a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.575
ENSMZEP00005014006	dnm2	ENSMZEP00005014006	ENSMZEP00005018289	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.575
ENSMZEP00005014006	dnm3	ENSMZEP00005014006	ENSMZEP00005026329	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.575
ENSMZEP00005019519	LOC101472092	ENSMZEP00005019519	ENSMZEP00005012250	Uncharacterized protein.	Uncharacterized protein.	0.512
ENSMZEP00005019519	RAMP3	ENSMZEP00005019519	ENSMZEP00005015660	Uncharacterized protein.	Receptor activity modifying protein 3.	0.516
ENSMZEP00005019519	ramp2	ENSMZEP00005019519	ENSMZEP00005030393	Uncharacterized protein.	Receptor (G protein-coupled) activity modifying protein 2.	0.512
LOC101463593	ENSMZEP00005014006	ENSMZEP00005012001	ENSMZEP00005014006	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.575
LOC101463593	LOC101471166	ENSMZEP00005012001	ENSMZEP00005013509	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.643
LOC101463593	LOC101475502	ENSMZEP00005012001	ENSMZEP00005017282	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.643
LOC101463593	cav3	ENSMZEP00005012001	ENSMZEP00005014017	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.528
LOC101463593	cltc	ENSMZEP00005012001	ENSMZEP00005031278	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.643