(35 nodes) Positive regulation of TOR signaling network (Maylandia zebra)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gpr137c	G protein-coupled receptor 137c. (451 aa)
	wdr59	WD repeat domain 59. (973 aa)
	LOC101480084	Uncharacterized protein. (381 aa)
	seh1l	SEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family. (367 aa)
	htr6	5-hydroxytryptamine (serotonin) receptor 6; Belongs to the G-protein coupled receptor 1 family. (452 aa)
	LOC101483657	G protein-coupled receptor 137Bb. (377 aa)
	golph3	Golgi phosphoprotein 3. (293 aa)
	LOC101471092	Uncharacterized protein. (161 aa)
	lamtor2	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa)
	lamtor3	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (133 aa)
	LOC101470757	Ras-related GTP binding D. (416 aa)
	flcn	Folliculin. (556 aa)
	wac	WW domain containing adaptor with coiled-coil a. (543 aa)
	mios	Missing oocyte, meiosis regulator, homolog (Drosophila). (884 aa)
	ctns	Cystinosin, lysosomal cystine transporter. (381 aa)
	LOC101477082	Ras-related GTP binding A. (315 aa)
	lamtor4	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (97 aa)
	rptor	Regulatory associated protein of MTOR, complex 1. (1350 aa)
	wdr24	WD repeat domain 24. (788 aa)
	rictor	RPTOR independent companion of MTOR, complex 2 a. (1724 aa)
	GPR137B	G protein-coupled receptor 137B. (386 aa)
	slc38a9	Solute carrier family 38 member 9. (558 aa)
	LOC101468451	WW domain-containing protein. (524 aa)
	rragc	Ras-related GTP binding Ca. (382 aa)
	clec16a	C-type lectin domain containing 16A. (1006 aa)
	sec13	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (320 aa)
	lamtor1	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (158 aa)
	klhl22	Kelch-like family member 22. (638 aa)
	lamtor5	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa)
	LOC101487497	G protein-coupled receptor 137. (382 aa)
	RELN	Reelin. (3454 aa)
	fnip1	Folliculin interacting protein 1. (1264 aa)
	gas6	Uncharacterized protein. (649 aa)
	lars1	Leucyl-tRNA synthetase b; Belongs to the class-I aminoacyl-tRNA synthetase family. (1184 aa)
	LOC101471956	Golgi phosphoprotein 3. (293 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101470757	LOC101477082	ENSMZEP00005022770	ENSMZEP00005020103	Ras-related GTP binding D.	Ras-related GTP binding A.	0.996
LOC101470757	LOC101480084	ENSMZEP00005022770	ENSMZEP00005035222	Ras-related GTP binding D.	Uncharacterized protein.	0.929
LOC101470757	flcn	ENSMZEP00005022770	ENSMZEP00005021908	Ras-related GTP binding D.	Folliculin.	0.990
LOC101470757	fnip1	ENSMZEP00005022770	ENSMZEP00005004595	Ras-related GTP binding D.	Folliculin interacting protein 1.	0.948
LOC101470757	lamtor1	ENSMZEP00005022770	ENSMZEP00005009833	Ras-related GTP binding D.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	0.968
LOC101470757	lamtor2	ENSMZEP00005022770	ENSMZEP00005023412	Ras-related GTP binding D.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	0.975
LOC101470757	lamtor3	ENSMZEP00005022770	ENSMZEP00005022811	Ras-related GTP binding D.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.	0.969
LOC101470757	lamtor4	ENSMZEP00005022770	ENSMZEP00005020048	Ras-related GTP binding D.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	0.962
LOC101470757	lamtor5	ENSMZEP00005022770	ENSMZEP00005008620	Ras-related GTP binding D.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5.	0.975
LOC101470757	lars1	ENSMZEP00005022770	ENSMZEP00005003527	Ras-related GTP binding D.	Leucyl-tRNA synthetase b; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.460
LOC101470757	mios	ENSMZEP00005022770	ENSMZEP00005020798	Ras-related GTP binding D.	Missing oocyte, meiosis regulator, homolog (Drosophila).	0.914
LOC101470757	rictor	ENSMZEP00005022770	ENSMZEP00005013484	Ras-related GTP binding D.	RPTOR independent companion of MTOR, complex 2 a.	0.416
LOC101470757	rptor	ENSMZEP00005022770	ENSMZEP00005015959	Ras-related GTP binding D.	Regulatory associated protein of MTOR, complex 1.	0.984
LOC101470757	rragc	ENSMZEP00005022770	ENSMZEP00005011059	Ras-related GTP binding D.	Ras-related GTP binding Ca.	0.929
LOC101470757	sec13	ENSMZEP00005022770	ENSMZEP00005010292	Ras-related GTP binding D.	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.	0.659
LOC101470757	seh1l	ENSMZEP00005022770	ENSMZEP00005033974	Ras-related GTP binding D.	SEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family.	0.700
LOC101470757	slc38a9	ENSMZEP00005022770	ENSMZEP00005011994	Ras-related GTP binding D.	Solute carrier family 38 member 9.	0.898
LOC101470757	wdr24	ENSMZEP00005022770	ENSMZEP00005015290	Ras-related GTP binding D.	WD repeat domain 24.	0.927
LOC101470757	wdr59	ENSMZEP00005022770	ENSMZEP00005037914	Ras-related GTP binding D.	WD repeat domain 59.	0.725
LOC101471956	sec13	ENSMZEP00005000767	ENSMZEP00005010292	Golgi phosphoprotein 3.	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.	0.412