72 items (Maylandia zebra) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	opa1	OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1032 aa)
	sox17	SRY-box transcription factor 17. (397 aa)
	LOC101481185	Mothers against decapentaplegic homolog. (503 aa)
	tbx3	T-box transcription factor 3a. (710 aa)
	LOC101474152	T-box transcription factor 5a. (525 aa)
	neb	Nebulin. (6169 aa)
	ENSMZEP00005025379	Uncharacterized protein. (113 aa)
	cby1	Chibby homolog 1 (Drosophila). (134 aa)
	LOC101465517	Von Willebrand factor A domain containing 5B2. (1028 aa)
	sema3d	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family. (812 aa)
	alpk2	Uncharacterized protein. (1490 aa)
	SOX18	SRY-box transcription factor 18. (563 aa)
	edn1	Endothelin 1. (201 aa)
	sirt6	Sirtuin 6. (351 aa)
	ptch2	Patched 2. (1488 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
	Nrap	LIM zinc-binding domain-containing protein. (105 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	LOC101469119	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	acadm	Acyl-CoA dehydrogenase medium chain. (424 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (229 aa)
	mef2a	Myocyte enhancer factor 2aa. (491 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (415 aa)
	ENSMZEP00005029959	Ig-like domain-containing protein. (1177 aa)
	ENSMZEP00005000054	Uncharacterized protein. (243 aa)
	LOC101469646	MADS-box domain-containing protein. (506 aa)
	sgcb	Sarcoglycan, beta (dystrophin-associated glycoprotein). (310 aa)
	LOC101483027	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (426 aa)
	LOC101474161	Uncharacterized protein. (1656 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (445 aa)
	LOC101470851	Ankyrin repeat and SOCS box containing 2b. (583 aa)
	irx3	Iroquois homeobox 3a. (444 aa)
	ENSMZEP00005007667	Uncharacterized protein. (321 aa)
	LOC101481780	Mesoderm posterior ba. (265 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
	LOC101466107	Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
	LOC101485614	Mothers against decapentaplegic homolog. (510 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2516 aa)
	kdm6b	Lysine (K)-specific demethylase 6B, a. (2185 aa)
	LOC101478337	MADS-box domain-containing protein. (450 aa)
	LOC101466778	Bone morphogenetic protein 16. (510 aa)
	LOC101473939	TSC complex subunit 1b. (1275 aa)
	ENSMZEP00005020489	MADS-box domain-containing protein. (477 aa)
	LOC101482600	Ankyrin repeat and SOCS box containing 2a, tandem duplicate 1. (683 aa)
	csrp3	Cysteine and glycine-rich protein 3 (cardiac LIM protein). (193 aa)
	mef2c	Myocyte enhancer factor 2cb. (517 aa)
	LOC101474873	Lysine (K)-specific demethylase 6B, b. (1737 aa)
	grem1	Gremlin 1a, DAN family BMP antagonist. (179 aa)
	maml1	Mastermind-like transcriptional coactivator 1. (972 aa)
	LOC101478377	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (407 aa)
	MYOCD	Myocardin. (1013 aa)
	ENSMZEP00005004331	T-box transcription factor 3b. (380 aa)
	LOC101485505	ADP-ribosylhydrolase like 1. (1049 aa)
	ednra	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (442 aa)
	nkx2-5	NK2 homeobox 5. (320 aa)
	LOC101474600	Si:dkey-49n23.1; Belongs to the semaphorin family. (799 aa)
	LOC101468649	Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (488 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	SRF	Serum response factor. (618 aa)
	bmp2	Bone morphogenetic protein 2b. (418 aa)
	ENSMZEP00005017086	Homeobox domain-containing protein. (286 aa)
	hand2	Heart and neural crest derivatives expressed 2. (245 aa)
	NOX4-2	FAD-binding FR-type domain-containing protein. (471 aa)
	NOX4	NADPH oxidase 4. (474 aa)
	tcap	Titin-cap (telethonin). (179 aa)
	ENSMZEP00005029962	Alpha-type protein kinase domain-containing protein. (194 aa)
	bmp4	Bone morphogenetic protein 4. (403 aa)
	Lrrc10b	Uncharacterized protein. (304 aa)
	tbx1	T-box transcription factor 1. (501 aa)
	LOC101467180	Mothers against decapentaplegic homolog. (494 aa)
	Lrrc10	Uncharacterized protein. (266 aa)
	LOC101485383	Mothers against decapentaplegic homolog. (606 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH2	LOC101469119	ENSMZEP00005033920	ENSMZEP00005033475	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.901
EDNRA	edn1	ENSMZEP00005011847	ENSMZEP00005035165	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.997
EDNRA	ednra	ENSMZEP00005011847	ENSMZEP00005012132	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.902
ENSMZEP00005000054	LOC101474873	ENSMZEP00005000054	ENSMZEP00005018325	Uncharacterized protein.	Lysine (K)-specific demethylase 6B, b.	0.722
ENSMZEP00005000054	kdm6b	ENSMZEP00005000054	ENSMZEP00005006107	Uncharacterized protein.	Lysine (K)-specific demethylase 6B, a.	0.722
ENSMZEP00005000054	mtor	ENSMZEP00005000054	ENSMZEP00005006208	Uncharacterized protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.907
ENSMZEP00005004331	nkx2-5	ENSMZEP00005004331	ENSMZEP00005011918	T-box transcription factor 3b.	NK2 homeobox 5.	0.487
ENSMZEP00005007667	nkx2-5	ENSMZEP00005007667	ENSMZEP00005011918	Uncharacterized protein.	NK2 homeobox 5.	0.471
ENSMZEP00005020489	MYOCD	ENSMZEP00005020489	ENSMZEP00005005039	MADS-box domain-containing protein.	Myocardin.	0.835
ENSMZEP00005020489	irx3	ENSMZEP00005020489	ENSMZEP00005008959	MADS-box domain-containing protein.	Iroquois homeobox 3a.	0.413
ENSMZEP00005020489	nkx2-5	ENSMZEP00005020489	ENSMZEP00005011918	MADS-box domain-containing protein.	NK2 homeobox 5.	0.450
ENSMZEP00005025379	Nrap	ENSMZEP00005025379	ENSMZEP00005033828	Uncharacterized protein.	LIM zinc-binding domain-containing protein.	0.413
ENSMZEP00005025379	tcap	ENSMZEP00005025379	ENSMZEP00005030646	Uncharacterized protein.	Titin-cap (telethonin).	0.542
ENSMZEP00005029959	ENSMZEP00005029962	ENSMZEP00005029959	ENSMZEP00005029962	Ig-like domain-containing protein.	Alpha-type protein kinase domain-containing protein.	0.889
ENSMZEP00005029962	ENSMZEP00005029959	ENSMZEP00005029962	ENSMZEP00005029959	Alpha-type protein kinase domain-containing protein.	Ig-like domain-containing protein.	0.889
LOC101466107	tgfb2	ENSMZEP00005006439	ENSMZEP00005033803	Transforming growth factor beta; Belongs to the TGF-beta family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.901
LOC101466778	LOC101467180	ENSMZEP00005021968	ENSMZEP00005022659	Bone morphogenetic protein 16.	Mothers against decapentaplegic homolog.	0.678
LOC101466778	LOC101481185	ENSMZEP00005021968	ENSMZEP00005024930	Bone morphogenetic protein 16.	Mothers against decapentaplegic homolog.	0.678
LOC101466778	LOC101485383	ENSMZEP00005021968	ENSMZEP00005023404	Bone morphogenetic protein 16.	Mothers against decapentaplegic homolog.	0.678
LOC101466778	LOC101485614	ENSMZEP00005021968	ENSMZEP00005006313	Bone morphogenetic protein 16.	Mothers against decapentaplegic homolog.	0.678