(28 nodes) Regulation of multicellular organism growth network (Maylandia zebra)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101464662	Adrenoceptor beta 3a; Belongs to the G-protein coupled receptor 1 family. (440 aa)
	ENSMZEP00005018204	Uncharacterized protein. (89 aa)
	ghsr	Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family. (384 aa)
	gpam	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (827 aa)
	mbd5	Methyl-CpG binding domain protein 5. (1495 aa)
	kmt5b	Lysine methyltransferase 5B. (867 aa)
	igf2	Insulin-like growth factor 2b. (215 aa)
	LOC101485857	Suppressor of cytokine signaling 2. (202 aa)
	FXN	Uncharacterized protein. (133 aa)
	LOC101477921	BH4_2 domain-containing protein. (198 aa)
	ENSMZEP00005028507	Prolactin releasing hormone 2. (121 aa)
	LOC101468393	Signal transducer and activator of transcription. (786 aa)
	ENSMZEP00005031626	Uncharacterized protein. (133 aa)
	LOC101471162	Uncharacterized protein. (264 aa)
	bcl2	BCL2 apoptosis regulator b. (228 aa)
	LOC101470833	Signal transducer and activator of transcription. (756 aa)
	LOC101485426	Signal transducer and activator of transcription. (786 aa)
	gdf15	TGF_BETA_2 domain-containing protein. (370 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
	fto	FTO alpha-ketoglutarate dependent dioxygenase. (658 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (825 aa)
	plac8	Placenta associated 8, tandem duplicate 1. (104 aa)
	LOC101487412	Adrenoceptor beta 2, surface a; Belongs to the G-protein coupled receptor 1 family. (417 aa)
	mkks	McKusick-Kaufman syndrome. (565 aa)
	lgmn	Legumain. (434 aa)
	ppib	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (214 aa)
	sgpl1	Sphingosine-1-phosphate lyase 1. (565 aa)
	bbs4	Bardet-Biedl syndrome 4. (369 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMZEP00005031626	FXN	ENSMZEP00005031626	ENSMZEP00005024671	Uncharacterized protein.	Uncharacterized protein.	0.900
FXN	ENSMZEP00005031626	ENSMZEP00005024671	ENSMZEP00005031626	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC101464662	LOC101487412	ENSMZEP00005016176	ENSMZEP00005011204	Adrenoceptor beta 3a; Belongs to the G-protein coupled receptor 1 family.	Adrenoceptor beta 2, surface a; Belongs to the G-protein coupled receptor 1 family.	0.779
LOC101468393	LOC101485426	ENSMZEP00005030492	ENSMZEP00005004305	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.900
LOC101468393	LOC101485857	ENSMZEP00005030492	ENSMZEP00005024518	Signal transducer and activator of transcription.	Suppressor of cytokine signaling 2.	0.418
LOC101470833	LOC101485857	ENSMZEP00005000245	ENSMZEP00005024518	Signal transducer and activator of transcription.	Suppressor of cytokine signaling 2.	0.418
LOC101477921	bcl2	ENSMZEP00005026868	ENSMZEP00005033977	BH4_2 domain-containing protein.	BCL2 apoptosis regulator b.	0.900
LOC101485426	LOC101468393	ENSMZEP00005004305	ENSMZEP00005030492	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.900
LOC101485426	LOC101485857	ENSMZEP00005004305	ENSMZEP00005024518	Signal transducer and activator of transcription.	Suppressor of cytokine signaling 2.	0.418
LOC101485857	LOC101468393	ENSMZEP00005024518	ENSMZEP00005030492	Suppressor of cytokine signaling 2.	Signal transducer and activator of transcription.	0.418
LOC101485857	LOC101470833	ENSMZEP00005024518	ENSMZEP00005000245	Suppressor of cytokine signaling 2.	Signal transducer and activator of transcription.	0.418
LOC101485857	LOC101485426	ENSMZEP00005024518	ENSMZEP00005004305	Suppressor of cytokine signaling 2.	Signal transducer and activator of transcription.	0.418
LOC101487412	LOC101464662	ENSMZEP00005011204	ENSMZEP00005016176	Adrenoceptor beta 2, surface a; Belongs to the G-protein coupled receptor 1 family.	Adrenoceptor beta 3a; Belongs to the G-protein coupled receptor 1 family.	0.779
bbs4	smo	ENSMZEP00005018093	ENSMZEP00005009518	Bardet-Biedl syndrome 4.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.710
bcl2	LOC101477921	ENSMZEP00005033977	ENSMZEP00005026868	BCL2 apoptosis regulator b.	BH4_2 domain-containing protein.	0.900
smo	bbs4	ENSMZEP00005009518	ENSMZEP00005018093	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	Bardet-Biedl syndrome 4.	0.710