(31 nodes) Positive regulation of DNA replication network (Maylandia zebra)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cdc7	Cell division cycle 7 homolog (S. cerevisiae). (611 aa)
	ucn	Urotensin 1. (148 aa)
	e2f7	E2F transcription factor 7. (790 aa)
	LOC101477591	Si:dkey-217d24.6. (754 aa)
	faf1	Fas (TNFRSF6) associated factor 1. (674 aa)
	atad5	ATPase family AAA domain containing 5a. (1807 aa)
	dna2	DNA replication helicase/nuclease 2. (1401 aa)
	atrx	ATRX chromatin remodeler. (1680 aa)
	LOC101481723	EGF-like domain-containing protein. (154 aa)
	ino80	INO80 complex ATPase subunit. (1506 aa)
	ENSMZEP00005018680	Uncharacterized protein. (1708 aa)
	dhx9	DEAH (Asp-Glu-Ala-His) box helicase 9. (1271 aa)
	e2f8	E2F transcription factor 8. (886 aa)
	LOC101475430	Bromodomain and PHD finger containing, 3a. (1227 aa)
	stoml2	Stomatin (EPB72)-like 2. (356 aa)
	BAZ1A	Bromodomain adjacent to zinc finger domain 1A. (1143 aa)
	cdt1	Chromatin licensing and DNA replication factor 1. (599 aa)
	LOC101464430	Cdkn1a interacting zinc finger protein 1a. (745 aa)
	LOC101483840	DBF4-type domain-containing protein. (862 aa)
	dbf4	DBF4 zinc finger. (613 aa)
	LOC101485137	AAA domain-containing protein. (853 aa)
	LOC101486034	E2F transcription factor 5. (360 aa)
	LOC101474682	Bromodomain and PHD finger containing, 3b. (1254 aa)
	ENSMZEP00005034571	Uncharacterized protein. (934 aa)
	LOC101483027	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (426 aa)
	ssbp1	Single-stranded DNA binding protein 1. (147 aa)
	egf	Epidermal growth factor. (953 aa)
	LOC101473641	Si:ch211-194b1.1. (2071 aa)
	LOC101478377	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (407 aa)
	ENSMZEP00005005357	Uncharacterized protein. (1056 aa)
	LOC106675102	Uncharacterized protein. (1000 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAZ1A	ENSMZEP00005018680	ENSMZEP00005022938	ENSMZEP00005018680	Bromodomain adjacent to zinc finger domain 1A.	Uncharacterized protein.	0.444
BAZ1A	atrx	ENSMZEP00005022938	ENSMZEP00005015462	Bromodomain adjacent to zinc finger domain 1A.	ATRX chromatin remodeler.	0.444
BAZ1A	ino80	ENSMZEP00005022938	ENSMZEP00005017492	Bromodomain adjacent to zinc finger domain 1A.	INO80 complex ATPase subunit.	0.438
ENSMZEP00005005357	LOC101485137	ENSMZEP00005005357	ENSMZEP00005032052	Uncharacterized protein.	AAA domain-containing protein.	0.445
ENSMZEP00005005357	atad5	ENSMZEP00005005357	ENSMZEP00005014868	Uncharacterized protein.	ATPase family AAA domain containing 5a.	0.445
ENSMZEP00005018680	BAZ1A	ENSMZEP00005018680	ENSMZEP00005022938	Uncharacterized protein.	Bromodomain adjacent to zinc finger domain 1A.	0.444
ENSMZEP00005034571	LOC101485137	ENSMZEP00005034571	ENSMZEP00005032052	Uncharacterized protein.	AAA domain-containing protein.	0.445
ENSMZEP00005034571	atad5	ENSMZEP00005034571	ENSMZEP00005014868	Uncharacterized protein.	ATPase family AAA domain containing 5a.	0.445
LOC101474682	LOC101485137	ENSMZEP00005038081	ENSMZEP00005032052	Bromodomain and PHD finger containing, 3b.	AAA domain-containing protein.	0.459
LOC101474682	atad5	ENSMZEP00005038081	ENSMZEP00005014868	Bromodomain and PHD finger containing, 3b.	ATPase family AAA domain containing 5a.	0.459
LOC101475430	LOC101485137	ENSMZEP00005019502	ENSMZEP00005032052	Bromodomain and PHD finger containing, 3a.	AAA domain-containing protein.	0.459
LOC101475430	atad5	ENSMZEP00005019502	ENSMZEP00005014868	Bromodomain and PHD finger containing, 3a.	ATPase family AAA domain containing 5a.	0.459
LOC101478377	LOC101483027	ENSMZEP00005005060	ENSMZEP00005000537	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.900
LOC101481723	egf	ENSMZEP00005016728	ENSMZEP00005001650	EGF-like domain-containing protein.	Epidermal growth factor.	0.812
LOC101483027	LOC101478377	ENSMZEP00005000537	ENSMZEP00005005060	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.	0.900
LOC101483840	cdc7	ENSMZEP00005028386	ENSMZEP00005005990	DBF4-type domain-containing protein.	Cell division cycle 7 homolog (S. cerevisiae).	0.982
LOC101483840	cdt1	ENSMZEP00005028386	ENSMZEP00005024781	DBF4-type domain-containing protein.	Chromatin licensing and DNA replication factor 1.	0.826
LOC101485137	ENSMZEP00005005357	ENSMZEP00005032052	ENSMZEP00005005357	AAA domain-containing protein.	Uncharacterized protein.	0.445
LOC101485137	ENSMZEP00005034571	ENSMZEP00005032052	ENSMZEP00005034571	AAA domain-containing protein.	Uncharacterized protein.	0.445
LOC101485137	LOC101474682	ENSMZEP00005032052	ENSMZEP00005038081	AAA domain-containing protein.	Bromodomain and PHD finger containing, 3b.	0.459