STRINGSTRING
prkaa1 prkaa1 LOC101477577 LOC101477577 ep300 ep300 gpr176 gpr176 Pspc1 Pspc1 ENSMZEP00005037770 ENSMZEP00005037770 LOC101468013 LOC101468013 ccdc90b ccdc90b PER2 PER2 LOC101472521 LOC101472521 huwe1 huwe1 LOC101468893 LOC101468893 ENSMZEP00005036203 ENSMZEP00005036203 LOC101480452 LOC101480452 fzd4 fzd4 LOC101470283 LOC101470283 LOC101464120 LOC101464120 sfpq sfpq pam pam LOC101476944 LOC101476944 sirt6 sirt6 LOC101485591 LOC101485591 LOC101483990 LOC101483990 LOC101470179 LOC101470179 LOC112434447 LOC112434447 ZNF830 ZNF830 cdk5 cdk5 LOC101474443 LOC101474443 LOC101471392 LOC101471392 LOC101478070 LOC101478070 nrip1 nrip1 LOC101477563 LOC101477563 LOC101487269 LOC101487269 LOC101486037 LOC101486037 EZH1 EZH1 LOC101486227 LOC101486227 LOC101474493 LOC101474493 kdm8 kdm8 LOC101479147 LOC101479147 scaper scaper timeless timeless adnp adnp tnfrsf11a tnfrsf11a ENSMZEP00005029175 ENSMZEP00005029175 Mycbp2 Mycbp2 fbxl3 fbxl3 LOC101479865 LOC101479865 ncoa2 ncoa2 per1 per1 impdh2 impdh2 tnfaip6 tnfaip6 enox1 enox1 CLOCK CLOCK mapk10 mapk10 LOC101467593 LOC101467593 nudt12 nudt12 prkaa2 prkaa2 nr0b2 nr0b2 LOC101479329 LOC101479329 LOC101484527 LOC101484527 LOC101467119 LOC101467119 LOC101470055 LOC101470055 piwil2 piwil2 LOC101478984 LOC101478984 LOC101487738 LOC101487738 LOC101463617 LOC101463617 bhlhe41 bhlhe41 LOC101486274 LOC101486274 LOC101466326 LOC101466326 nr1d2 nr1d2 CRTC1 CRTC1 ndufa9 ndufa9 GRIN3A GRIN3A LOC101471314 LOC101471314 LOC101468046 LOC101468046 LOC101465325 LOC101465325 LOC101473958 LOC101473958 LOC101479683 LOC101479683 LOC101469226 LOC101469226 LOC101478720 LOC101478720 LOC101465117 LOC101465117 LOC101475433 LOC101475433 LOC101473075 LOC101473075 ARNTL2 ARNTL2 LOC101465128 LOC101465128 LOC101487557 LOC101487557 LOC101477095 LOC101477095 ENSMZEP00005000180 ENSMZEP00005000180 ENSMZEP00005000240 ENSMZEP00005000240 hlf hlf LOC101470707 LOC101470707 AANAT AANAT lgr4 lgr4 GPR149 GPR149 ppargc1a ppargc1a LOC101466237 LOC101466237 LOC101477322 LOC101477322 LOC101470054 LOC101470054 LOC101470350 LOC101470350 gas2 gas2 LOC101472635 LOC101472635 LOC101475123 LOC101475123 LOC101464395 LOC101464395 ppp1cc ppp1cc ENSMZEP00005003923 ENSMZEP00005003923 LOC101486563 LOC101486563 naglu naglu dhx9 dhx9 PPARG PPARG ddb1 ddb1 atg7 atg7 LOC101464777 LOC101464777 ezh2 ezh2 LOC101476882 LOC101476882 egr3 egr3 LOC101481723 LOC101481723 LOC101468757 LOC101468757 egr1 egr1 prmt5 prmt5 ppara ppara LOC101463775 LOC101463775 LOC101487279 LOC101487279 ENSMZEP00005015751 ENSMZEP00005015751 noct noct sgpl1 sgpl1 LOC112433079 LOC112433079 sirt1 sirt1 LOC101481017 LOC101481017 ptx3 ptx3 LOC112435213 LOC112435213 nampt nampt rorb rorb LOC101467328 LOC101467328 ogt ogt LOC101471717 LOC101471717 Nono Nono PPARA PPARA LOC101483346 LOC101483346 LOC101481870 LOC101481870 LOC101481574 LOC101481574 Mybbp1a Mybbp1a id1 id1 bhlhe40 bhlhe40 ENSMZEP00005012266 ENSMZEP00005012266 LOC101474441 LOC101474441 LOC101486750 LOC101486750 enox2 enox2 ncor2 ncor2 DNM1L DNM1L lg16h3orf70 lg16h3orf70 BHLHE40 BHLHE40 gpr157 gpr157 mtnr1a mtnr1a ncor1 ncor1 kiaa2013 kiaa2013 mapk8 mapk8 sp1 sp1 LOC101468050 LOC101468050 nfya nfya LOC111501698 LOC111501698 btbd9 btbd9 LOC101477504 LOC101477504 atf4 atf4 pspc1 pspc1 LOC101466338 LOC101466338 id2 id2 csnk1e csnk1e HDAC3 HDAC3 LOC101477349 LOC101477349 mtor mtor LOC101470946 LOC101470946 crebbp crebbp LOC101483328 LOC101483328 LOC101474249 LOC101474249 nr1d1 nr1d1 LOC101467023 LOC101467023 LOC101481701 LOC101481701
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
prkaa1Non-specific serine/threonine protein kinase. (571 aa)
LOC101477577Mitogen-activated protein kinase. (410 aa)
ep300E1A binding protein p300 b. (2765 aa)
gpr176G protein-coupled receptor 176. (574 aa)
Pspc1RRM domain-containing protein. (172 aa)
ENSMZEP00005037770Uncharacterized protein. (147 aa)
LOC101468013E1A binding protein p300 a. (2775 aa)
ccdc90bCoiled-coil domain containing 90B. (238 aa)
PER2Period circadian regulator 2. (1491 aa)
LOC1014725215-hydroxytryptamine (serotonin) receptor 7a; Belongs to the G-protein coupled receptor 1 family. (491 aa)
huwe1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4098 aa)
LOC101468893Nuclear receptor subfamily 1, group D, member 4a. (581 aa)
ENSMZEP00005036203Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (527 aa)
LOC101480452Cryptochrome circadian regulator 3a. (654 aa)
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (533 aa)
LOC101470283DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (567 aa)
LOC101464120Circadian associated repressor of transcription a. (372 aa)
sfpqSplicing factor proline/glutamine-rich. (665 aa)
pamPeptidylglycine alpha-amidating monooxygenase. (766 aa)
LOC101476944RAR-related orphan receptor C b. (502 aa)
sirt6Sirtuin 6. (351 aa)
LOC101485591Period circadian clock 2. (1437 aa)
LOC101483990Inhibitor of DNA binding 4. (141 aa)
LOC101470179Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1139 aa)
LOC112434447WD_REPEATS_REGION domain-containing protein. (526 aa)
ZNF830Zinc finger protein 830. (348 aa)
cdk5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
LOC101474443Nuclear factor, interleukin 3 regulated. (455 aa)
LOC101471392E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (332 aa)
LOC101478070Clock circadian regulator b. (882 aa)
nrip1Nuclear receptor interacting protein 1b. (1199 aa)
LOC101477563Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (332 aa)
LOC101487269Nerve growth factor receptor a (TNFR superfamily, member 16). (285 aa)
LOC101486037Cryptochrome circadian regulator 2. (673 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (766 aa)
LOC101486227Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (383 aa)
LOC101474493Uncharacterized protein. (366 aa)
kdm8Lysine (K)-specific demethylase 8. (408 aa)
LOC101479147Arylalkylamine N-acetyltransferase 2. (210 aa)
scaperS-phase cyclin A-associated protein in the ER. (1484 aa)
timelessTimeless circadian clock. (1249 aa)
adnpActivity-dependent neuroprotector homeobox b. (1056 aa)
tnfrsf11aTumor necrosis factor receptor superfamily, member 11a, NFKB activator. (649 aa)
ENSMZEP00005029175Uncharacterized protein. (369 aa)
Mycbp2RING-type domain-containing protein. (497 aa)
fbxl3F-box and leucine-rich repeat protein 3a. (437 aa)
LOC101479865Period circadian clock 3. (1234 aa)
ncoa2Nuclear receptor coactivator. (1461 aa)
per1Period circadian clock 1b. (1417 aa)
impdh2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (538 aa)
tnfaip6Tumor necrosis factor, alpha-induced protein 6. (256 aa)
enox1RRM domain-containing protein. (600 aa)
CLOCKClock circadian regulator a. (790 aa)
mapk10Mitogen-activated protein kinase. (402 aa)
LOC101467593Si:ch1073-390k14.1. (840 aa)
nudt12Nudix (nucleoside diphosphate linked moiety X)-type motif 12. (456 aa)
prkaa2Non-specific serine/threonine protein kinase. (557 aa)
nr0b2Nuclear receptor subfamily 0, group B, member 2a. (258 aa)
LOC101479329Melatonin receptor 1Bb; Belongs to the G-protein coupled receptor 1 family. (337 aa)
LOC101484527Casein kinase 1, epsilon; Belongs to the protein kinase superfamily. (420 aa)
LOC101467119Activating transcription factor 5b. (505 aa)
LOC101470055Aryl hydrocarbon receptor nuclear translocator-like 2. (638 aa)
piwil2Piwi-like RNA-mediated gene silencing 2; Belongs to the argonaute family. (1067 aa)
LOC1014789845-hydroxytryptamine (serotonin) receptor 7b. (408 aa)
LOC101487738Uncharacterized protein. (947 aa)
LOC101463617Uncharacterized protein. (970 aa)
bhlhe41Basic helix-loop-helix family, member e41. (430 aa)
LOC101486274Homer scaffold protein 1b. (363 aa)
LOC101466326Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1122 aa)
nr1d2Nuclear receptor subfamily 1, group D, member 2b. (590 aa)
CRTC1CREB regulated transcription coactivator 1b. (604 aa)
ndufa9NADH:ubiquinone oxidoreductase subunit A9a. (382 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1048 aa)
LOC101471314Activating transcription factor 5a. (505 aa)
LOC101468046DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (747 aa)
LOC101465325D site albumin promoter binding protein b. (373 aa)
LOC101473958G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (367 aa)
LOC101479683Nuclear receptor subfamily 1, group D, member 2a. (597 aa)
LOC101469226Circadian associated repressor of transcription. (420 aa)
LOC101478720Aryl hydrocarbon receptor 2. (958 aa)
LOC101465117Aryl hydrocarbon receptor 1b. (794 aa)
LOC101475433Neuronal PAS domain protein 2. (872 aa)
LOC101473075G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (414 aa)
ARNTL2Aryl hydrocarbon receptor nuclear translocator like 2. (541 aa)
LOC101465128Aryl hydrocarbon receptor nuclear translocator-like 1a. (602 aa)
LOC101487557Nerve growth factor receptor b. (427 aa)
LOC101477095Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (325 aa)
ENSMZEP00005000180Uncharacterized protein. (380 aa)
ENSMZEP00005000240Period_C domain-containing protein. (522 aa)
hlfBZIP domain-containing protein. (297 aa)
LOC101470707Denticleless E3 ubiquitin protein ligase homolog (Drosophila). (661 aa)
AANATArylalkylamine N-acetyltransferase 1. (202 aa)
lgr4Leucine-rich repeat containing G protein-coupled receptor 4. (978 aa)
GPR149G protein-coupled receptor 149. (774 aa)
ppargc1aPeroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (1283 aa)
LOC101466237Family with sequence similarity 155 member A. (385 aa)
LOC101477322Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
LOC101470054Nuclear factor, interleukin 3 regulated, member 6. (407 aa)
LOC101470350BZIP domain-containing protein. (623 aa)
gas2Growth arrest-specific 2a. (336 aa)
LOC101472635Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (333 aa)
LOC101475123D site albumin promoter binding protein a. (377 aa)
LOC101464395Pleiotrophin. (164 aa)
ppp1ccSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
ENSMZEP00005003923BZIP domain-containing protein. (371 aa)
LOC101486563F-box domain-containing protein. (434 aa)
nagluN-acetylglucosaminidase, alpha. (752 aa)
dhx9DEAH (Asp-Glu-Ala-His) box helicase 9. (1271 aa)
PPARGPeroxisome proliferator activated receptor gamma. (555 aa)
ddb1Damage-specific DNA binding protein 1. (1140 aa)
atg7ATG7 autophagy related 7 homolog (S. cerevisiae). (722 aa)
LOC101464777SET domain-containing protein. (624 aa)
ezh2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (763 aa)
LOC101476882Mitogen-activated protein kinase. (420 aa)
egr3Early growth response 3. (410 aa)
LOC101481723EGF-like domain-containing protein. (154 aa)
LOC101468757Si:dkey-32e23.4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (673 aa)
egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (514 aa)
prmt5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (631 aa)
pparaPeroxisome proliferator-activated receptor alpha a. (475 aa)
LOC101463775F-box and leucine-rich repeat protein 3, like. (426 aa)
LOC101487279Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (573 aa)
ENSMZEP00005015751Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (120 aa)
noctNocturnin a. (393 aa)
sgpl1Sphingosine-1-phosphate lyase 1. (565 aa)
LOC112433079WD_REPEATS_REGION domain-containing protein. (554 aa)
sirt1Deacetylase sirtuin-type domain-containing protein. (715 aa)
LOC101481017CLOCK-interacting pacemaker b. (373 aa)
ptx3Pentraxin 3, long b. (457 aa)
LOC112435213Nuclear factor, interleukin 3 regulated. (438 aa)
namptNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (491 aa)
rorbRAR-related orphan receptor B. (476 aa)
LOC101467328HLF transcription factor, PAR bZIP family member b. (309 aa)
ogtO-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1. (1048 aa)
LOC101471717Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b. (407 aa)
NonoNon-POU domain containing, octamer-binding. (375 aa)
PPARAPeroxisome proliferator-activated receptor alpha b. (469 aa)
LOC101483346DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (755 aa)
LOC101481870Nuclear factor, interleukin 3 regulated, member 5. (611 aa)
LOC101481574BZIP domain-containing protein. (403 aa)
Mybbp1aUncharacterized protein. (300 aa)
id1Inhibitor of DNA binding 1, HLH protein. (131 aa)
bhlhe40Basic helix-loop-helix family, member e40. (412 aa)
ENSMZEP00005012266Uncharacterized protein. (164 aa)
LOC101474441Cryptochrome circadian regulator 5. (518 aa)
LOC101486750Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
enox2Ecto-NOX disulfide-thiol exchanger 2. (742 aa)
ncor2Nuclear receptor corepressor 2. (2295 aa)
DNM1LDynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (721 aa)
lg16h3orf70Zgc:162707. (290 aa)
BHLHE40Basic helix-loop-helix family member e40. (426 aa)
gpr157G protein-coupled receptor 157. (332 aa)
mtnr1aMelatonin receptor 1A a; Belongs to the G-protein coupled receptor 1 family. (350 aa)
ncor1Nuclear receptor corepressor 1. (2161 aa)
kiaa2013Si:dkeyp-104h9.5. (605 aa)
mapk8Mitogen-activated protein kinase. (384 aa)
sp1Sp1 transcription factor. (707 aa)
LOC101468050Nuclear receptor subfamily 1, group D, member 4b. (587 aa)
nfyaNuclear transcription factor Y, alpha, like. (346 aa)
LOC111501698BZIP domain-containing protein. (252 aa)
btbd9BTB (POZ) domain containing 9. (614 aa)
LOC101477504Hairy-related 11. (277 aa)
atf4Activating transcription factor 4a. (438 aa)
pspc1Paraspeckle component 1. (498 aa)
LOC101466338RAR-related orphan receptor C a. (474 aa)
id2Inhibitor of DNA binding 2a. (136 aa)
csnk1eProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (417 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
LOC101477349Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (792 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2516 aa)
LOC101470946N-acetyltransferase domain-containing protein. (225 aa)
crebbpCREB binding protein b. (2473 aa)
LOC101483328Nuclear receptor coactivator. (1464 aa)
LOC101474249Inhibitor of DNA binding 3. (117 aa)
nr1d1Nuclear receptor subfamily 1, group d, member 1. (602 aa)
LOC101467023CREB binding protein a. (2368 aa)
LOC101481701CREB regulated transcription coactivator 1a. (584 aa)
Your Current Organism:
Maylandia zebra
NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna
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