STRINGSTRING
LOC112430059 LOC112430059 fgf1 fgf1 LOC101466239 LOC101466239 lpcat3 lpcat3 LOC101474512 LOC101474512 igf2 igf2 DGKQ DGKQ nr1d1 nr1d1 apob apob asah1 asah1 sf1 sf1 scap scap podn podn sirt1 sirt1 LOC101468745 LOC101468745 dkk3 dkk3 DKK3 DKK3 h6pd h6pd rusc1 rusc1 abcg4 abcg4 LOC101469388 LOC101469388 dab2 dab2 srebf2 srebf2 cga cga LOC101468050 LOC101468050 LOC101471092 LOC101471092 NR0B1 NR0B1 armc5 armc5 snai2 snai2 LOC101471249 LOC101471249 ABCG1 ABCG1 LOC101469343 LOC101469343 srebf1 srebf1 ENSMZEP00005000347 ENSMZEP00005000347 fgf19 fgf19 LOC101469924 LOC101469924 ENSMZEP00005000375 ENSMZEP00005000375 LOC101484273 LOC101484273
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC112430059ATP-binding cassette, sub-family G (WHITE), member 1. (675 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (182 aa)
LOC101466239Apolipoprotein Eb. (276 aa)
lpcat3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (464 aa)
LOC101474512ATP-binding cassette, sub-family G (WHITE), member 4b. (645 aa)
igf2Insulin-like growth factor 2b. (215 aa)
DGKQDiacylglycerol kinase. (919 aa)
nr1d1Nuclear receptor subfamily 1, group d, member 1. (602 aa)
apobApolipoprotein Ba. (4368 aa)
asah1N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family. (392 aa)
sf1Splicing factor 1. (680 aa)
scapSREBF chaperone. (1326 aa)
podnPodocan. (586 aa)
sirt1Deacetylase sirtuin-type domain-containing protein. (715 aa)
LOC101468745Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
dkk3Dickkopf WNT signaling pathway inhibitor 3a. (270 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (270 aa)
h6pdHexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase). (791 aa)
rusc1RUN and SH3 domain containing 1. (1211 aa)
abcg4ATP-binding cassette, sub-family G (WHITE), member 4a. (640 aa)
LOC101469388NR LBD domain-containing protein. (258 aa)
dab2DAB adaptor protein 2. (778 aa)
srebf2Sterol regulatory element binding transcription factor 2. (1178 aa)
cgaGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (111 aa)
LOC101468050Nuclear receptor subfamily 1, group D, member 4b. (587 aa)
LOC101471092Uncharacterized protein. (161 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (296 aa)
armc5Armadillo repeat containing 5. (814 aa)
snai2Snail family zinc finger 2. (260 aa)
LOC101471249Apolipoprotein Ea. (262 aa)
ABCG1ATP binding cassette subfamily G member 1. (622 aa)
LOC101469343Apolipoprotein Bb, tandem duplicate 2. (3682 aa)
srebf1Sterol regulatory element binding transcription factor 1. (1136 aa)
ENSMZEP00005000347Vitellogenin domain-containing protein. (763 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC101469924Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
ENSMZEP00005000375Uncharacterized protein. (420 aa)
LOC101484273START domain-containing protein. (278 aa)
Your Current Organism:
Maylandia zebra
NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna
Server load: low (20%) [HD]