(38 nodes) Defense response to Gram-negative bacterium network (Maylandia zebra)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSMZEP00005037269	annotation not available (95 aa)
	IL12B	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (310 aa)
	LOC101482073	Interleukin 17a/f1. (155 aa)
	ENSMZEP00005004320	Uncharacterized protein. (142 aa)
	rpl30	Ribosomal protein L30. (116 aa)
	mpeg1	Macrophage expressed 1, tandem duplicate 2. (699 aa)
	LOC101486517	Uncharacterized protein. (233 aa)
	LOC101474867	Uncharacterized protein. (241 aa)
	ENSMZEP00005010167	CARD domain-containing protein. (151 aa)
	ENSMZEP00005010894	BPI1 domain-containing protein. (108 aa)
	LOC101480548	Uncharacterized protein. (472 aa)
	LOC101487119	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (347 aa)
	serpine1	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (390 aa)
	ENSMZEP00005013120	CARD domain-containing protein. (82 aa)
	ENSMZEP00005013126	CARD domain-containing protein. (95 aa)
	ENSMZEP00005013186	Uncharacterized protein. (216 aa)
	ENSMZEP00005013160	Pyrin domain-containing protein. (112 aa)
	ENSMZEP00005013211	Uncharacterized protein. (223 aa)
	ENSMZEP00005013222	Uncharacterized protein. (181 aa)
	ENSMZEP00005013228	CARD domain-containing protein. (85 aa)
	LOC101477799	Uncharacterized protein; Belongs to the peptidase S1 family. (489 aa)
	LOC101463683	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (611 aa)
	LOC101470099	Tumor suppressor 2, mitochondrial calcium regulator b. (111 aa)
	chga	Chromogranin A. (364 aa)
	ENSMZEP00005034826	Uncharacterized protein. (201 aa)
	ENSMZEP00005034602	CARD domain-containing protein. (95 aa)
	LOC101482032	Uncharacterized protein. (274 aa)
	tusc2	Tumor suppressor 2, mitochondrial calcium regulator. (109 aa)
	drosha	Drosha ribonuclease III. (1362 aa)
	ENSMZEP00005030519	Uncharacterized protein. (170 aa)
	LOC101477105	Uncharacterized protein. (460 aa)
	LOC112432292	BPI1 domain-containing protein. (121 aa)
	LOC101477423	Aquaporin 1a (Colton blood group), tandem duplicate 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (267 aa)
	ENSMZEP00005037259	CARD domain-containing protein. (93 aa)
	LOC101477702	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (258 aa)
	LOC101477140	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (261 aa)
	ENSMZEP00005037260	CARD domain-containing protein. (96 aa)
	LOC112434364	TNFR-Cys domain-containing protein. (298 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMZEP00005004320	ENSMZEP00005030519	ENSMZEP00005004320	ENSMZEP00005030519	Uncharacterized protein.	Uncharacterized protein.	0.590
ENSMZEP00005004320	LOC101482073	ENSMZEP00005004320	ENSMZEP00005004302	Uncharacterized protein.	Interleukin 17a/f1.	0.493
ENSMZEP00005013186	ENSMZEP00005013211	ENSMZEP00005013186	ENSMZEP00005013211	Uncharacterized protein.	Uncharacterized protein.	0.543
ENSMZEP00005013186	ENSMZEP00005013222	ENSMZEP00005013186	ENSMZEP00005013222	Uncharacterized protein.	Uncharacterized protein.	0.547
ENSMZEP00005013186	ENSMZEP00005034826	ENSMZEP00005013186	ENSMZEP00005034826	Uncharacterized protein.	Uncharacterized protein.	0.545
ENSMZEP00005013211	ENSMZEP00005013186	ENSMZEP00005013211	ENSMZEP00005013186	Uncharacterized protein.	Uncharacterized protein.	0.543
ENSMZEP00005013211	ENSMZEP00005013222	ENSMZEP00005013211	ENSMZEP00005013222	Uncharacterized protein.	Uncharacterized protein.	0.547
ENSMZEP00005013211	ENSMZEP00005034826	ENSMZEP00005013211	ENSMZEP00005034826	Uncharacterized protein.	Uncharacterized protein.	0.545
ENSMZEP00005013222	ENSMZEP00005013186	ENSMZEP00005013222	ENSMZEP00005013186	Uncharacterized protein.	Uncharacterized protein.	0.547
ENSMZEP00005013222	ENSMZEP00005013211	ENSMZEP00005013222	ENSMZEP00005013211	Uncharacterized protein.	Uncharacterized protein.	0.547
ENSMZEP00005013222	ENSMZEP00005034826	ENSMZEP00005013222	ENSMZEP00005034826	Uncharacterized protein.	Uncharacterized protein.	0.546
ENSMZEP00005030519	ENSMZEP00005004320	ENSMZEP00005030519	ENSMZEP00005004320	Uncharacterized protein.	Uncharacterized protein.	0.590
ENSMZEP00005030519	LOC101482073	ENSMZEP00005030519	ENSMZEP00005004302	Uncharacterized protein.	Interleukin 17a/f1.	0.907
ENSMZEP00005034826	ENSMZEP00005013186	ENSMZEP00005034826	ENSMZEP00005013186	Uncharacterized protein.	Uncharacterized protein.	0.545
ENSMZEP00005034826	ENSMZEP00005013211	ENSMZEP00005034826	ENSMZEP00005013211	Uncharacterized protein.	Uncharacterized protein.	0.545
ENSMZEP00005034826	ENSMZEP00005013222	ENSMZEP00005034826	ENSMZEP00005013222	Uncharacterized protein.	Uncharacterized protein.	0.546
IL12B	LOC101487119	ENSMZEP00005000817	ENSMZEP00005011300	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily.	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily.	0.904
LOC101463683	LOC101477799	ENSMZEP00005016587	ENSMZEP00005016388	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.901
LOC101463683	serpine1	ENSMZEP00005016587	ENSMZEP00005012705	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.	0.435
LOC101477105	LOC101480548	ENSMZEP00005032898	ENSMZEP00005010956	Uncharacterized protein.	Uncharacterized protein.	0.900