(20 nodes) Regulation of antigen receptor-mediated signaling pathway network (Maylandia zebra)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101477977	Phosphohistidine phosphatase 1. (128 aa)
	LOC101479549	MALT paracaspase 2. (823 aa)
	LOC101469098	Si:dkey-51e6.1. (143 aa)
	sh2d1a	SH2 domain containing 1A duplicate b. (154 aa)
	card11	Caspase recruitment domain family, member 11. (1162 aa)
	LOC101476790	KRAP_IP3R_bind domain-containing protein. (671 aa)
	cmtm3	CKLF-like MARVEL transmembrane domain containing 3. (171 aa)
	pawr	PRKC, apoptosis, WT1, regulator. (348 aa)
	LOC101480081	Si:ch211-25d12.7. (252 aa)
	ccr7	Chemokine (C-C motif) receptor 7; Belongs to the G-protein coupled receptor 1 family. (376 aa)
	kcnn4	Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4. (480 aa)
	LOC101473126	MALT paracaspase 1. (828 aa)
	slc39a10	Solute carrier family 39 member 10. (825 aa)
	ptprc	Protein tyrosine phosphatase receptor type C. (1195 aa)
	slc39a6	Solute carrier family 39 member 6. (754 aa)
	cd226	CD226 molecule. (316 aa)
	LOC101466152	MALT paracaspase 3. (548 aa)
	bcl10	BCL10 immune signaling adaptor. (248 aa)
	rc3h1	Ring finger and CCCH-type domains 1b. (1125 aa)
	RAB29	RAB29, member RAS oncogene family. (207 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101466152	bcl10	ENSMZEP00005029958	ENSMZEP00005032924	MALT paracaspase 3.	BCL10 immune signaling adaptor.	0.964
LOC101466152	card11	ENSMZEP00005029958	ENSMZEP00005009333	MALT paracaspase 3.	Caspase recruitment domain family, member 11.	0.893
LOC101473126	LOC101479549	ENSMZEP00005018146	ENSMZEP00005012080	MALT paracaspase 1.	MALT paracaspase 2.	0.903
LOC101473126	bcl10	ENSMZEP00005018146	ENSMZEP00005032924	MALT paracaspase 1.	BCL10 immune signaling adaptor.	0.996
LOC101473126	card11	ENSMZEP00005018146	ENSMZEP00005009333	MALT paracaspase 1.	Caspase recruitment domain family, member 11.	0.893
LOC101476790	cd226	ENSMZEP00005009008	ENSMZEP00005028729	KRAP_IP3R_bind domain-containing protein.	CD226 molecule.	0.468
LOC101479549	LOC101473126	ENSMZEP00005012080	ENSMZEP00005018146	MALT paracaspase 2.	MALT paracaspase 1.	0.903
LOC101479549	bcl10	ENSMZEP00005012080	ENSMZEP00005032924	MALT paracaspase 2.	BCL10 immune signaling adaptor.	0.996
LOC101479549	card11	ENSMZEP00005012080	ENSMZEP00005009333	MALT paracaspase 2.	Caspase recruitment domain family, member 11.	0.893
bcl10	LOC101466152	ENSMZEP00005032924	ENSMZEP00005029958	BCL10 immune signaling adaptor.	MALT paracaspase 3.	0.964
bcl10	LOC101473126	ENSMZEP00005032924	ENSMZEP00005018146	BCL10 immune signaling adaptor.	MALT paracaspase 1.	0.996
bcl10	LOC101479549	ENSMZEP00005032924	ENSMZEP00005012080	BCL10 immune signaling adaptor.	MALT paracaspase 2.	0.996
bcl10	card11	ENSMZEP00005032924	ENSMZEP00005009333	BCL10 immune signaling adaptor.	Caspase recruitment domain family, member 11.	0.979
card11	LOC101466152	ENSMZEP00005009333	ENSMZEP00005029958	Caspase recruitment domain family, member 11.	MALT paracaspase 3.	0.893
card11	LOC101473126	ENSMZEP00005009333	ENSMZEP00005018146	Caspase recruitment domain family, member 11.	MALT paracaspase 1.	0.893
card11	LOC101479549	ENSMZEP00005009333	ENSMZEP00005012080	Caspase recruitment domain family, member 11.	MALT paracaspase 2.	0.893
card11	bcl10	ENSMZEP00005009333	ENSMZEP00005032924	Caspase recruitment domain family, member 11.	BCL10 immune signaling adaptor.	0.979
ccr7	ptprc	ENSMZEP00005016703	ENSMZEP00005025150	Chemokine (C-C motif) receptor 7; Belongs to the G-protein coupled receptor 1 family.	Protein tyrosine phosphatase receptor type C.	0.607
cd226	LOC101476790	ENSMZEP00005028729	ENSMZEP00005009008	CD226 molecule.	KRAP_IP3R_bind domain-containing protein.	0.468
ptprc	ccr7	ENSMZEP00005025150	ENSMZEP00005016703	Protein tyrosine phosphatase receptor type C.	Chemokine (C-C motif) receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.607