(7 nodes) Telomeric loop disassembly network (Maylandia zebra)

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Your Input:
	slx4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1727 aa)
	terf2	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (509 aa)
	pot1	Protection of telomeres 1 homolog. (669 aa)
	ENSMZEP00005035748	RecQ helicase-like 4. (770 aa)
	LOC101471057	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1131 aa)
	blm	BLM RecQ like helicase. (1381 aa)
	LOC101487114	HTH myb-type domain-containing protein. (706 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMZEP00005035748	LOC101471057	ENSMZEP00005035748	ENSMZEP00005009509	RecQ helicase-like 4.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.747
ENSMZEP00005035748	LOC101487114	ENSMZEP00005035748	ENSMZEP00005012968	RecQ helicase-like 4.	HTH myb-type domain-containing protein.	0.465
ENSMZEP00005035748	pot1	ENSMZEP00005035748	ENSMZEP00005030327	RecQ helicase-like 4.	Protection of telomeres 1 homolog.	0.716
ENSMZEP00005035748	slx4	ENSMZEP00005035748	ENSMZEP00005004897	RecQ helicase-like 4.	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).	0.653
ENSMZEP00005035748	terf2	ENSMZEP00005035748	ENSMZEP00005012928	RecQ helicase-like 4.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.465
LOC101471057	ENSMZEP00005035748	ENSMZEP00005009509	ENSMZEP00005035748	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	RecQ helicase-like 4.	0.747
LOC101471057	blm	ENSMZEP00005009509	ENSMZEP00005029946	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	BLM RecQ like helicase.	0.814
LOC101471057	pot1	ENSMZEP00005009509	ENSMZEP00005030327	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	Protection of telomeres 1 homolog.	0.630
LOC101471057	slx4	ENSMZEP00005009509	ENSMZEP00005004897	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).	0.755
LOC101487114	ENSMZEP00005035748	ENSMZEP00005012968	ENSMZEP00005035748	HTH myb-type domain-containing protein.	RecQ helicase-like 4.	0.465
LOC101487114	blm	ENSMZEP00005012968	ENSMZEP00005029946	HTH myb-type domain-containing protein.	BLM RecQ like helicase.	0.596
LOC101487114	pot1	ENSMZEP00005012968	ENSMZEP00005030327	HTH myb-type domain-containing protein.	Protection of telomeres 1 homolog.	0.941
LOC101487114	slx4	ENSMZEP00005012968	ENSMZEP00005004897	HTH myb-type domain-containing protein.	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).	0.940
blm	LOC101471057	ENSMZEP00005029946	ENSMZEP00005009509	BLM RecQ like helicase.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.814
blm	LOC101487114	ENSMZEP00005029946	ENSMZEP00005012968	BLM RecQ like helicase.	HTH myb-type domain-containing protein.	0.596
blm	pot1	ENSMZEP00005029946	ENSMZEP00005030327	BLM RecQ like helicase.	Protection of telomeres 1 homolog.	0.748
blm	slx4	ENSMZEP00005029946	ENSMZEP00005004897	BLM RecQ like helicase.	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).	0.779
blm	terf2	ENSMZEP00005029946	ENSMZEP00005012928	BLM RecQ like helicase.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.596
pot1	ENSMZEP00005035748	ENSMZEP00005030327	ENSMZEP00005035748	Protection of telomeres 1 homolog.	RecQ helicase-like 4.	0.716
pot1	LOC101471057	ENSMZEP00005030327	ENSMZEP00005009509	Protection of telomeres 1 homolog.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.630